Precision bipolar current-mode digital-to-analog converter

• US 9,735,798 B2
• Filed: 08/07/2014
• Issued: 08/15/2017
• Est. Priority Date: 08/07/2013
• Status: Expired due to Fees

• Current Assignee: General Atomics, Inc.
• Original Assignee: Xagenic Inc
• Inventors: Chan, Wen
• Primary Examiner(s): YOUNG, BRIAN K
• Application Number:
  US14/454,685
• Publication Number:
  US 20150041317A1
• Time in Patent Office: 1,104 Days
• Field of Search: 341144, 341127
• CPC Class Codes: G01N 27/3275 Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
• CPC Class Codes: H03M 1/0607 Offset or drift compensation removal of offset already present on the analogue input signal H03M1/1295
• CPC Class Codes: H03M 1/66 Digital/analogue converters H03M1/001 – H03M1/10 take precedence

Abstract

A precision bipolar digital-to-analog converter (DAC) that provides a bipolar current output having a substantially fixed zero center point is provided. The DAC includes digital-to-analog converter circuitry configured to provide, responsive to a reference signal indicative of the digital data, a first analog current signal having a first potential and a second analog current signal having a second potential, subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point, and first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

Claims

1. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential set by a voltage source external to the DAC, and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

2. The DAC of claim 1, wherein the DAC is configured to provide the bipolar current signal having the zero center point without calibration or trimming.

3. The DAC of claim 1, wherein at least one of the first and second analog current signals is substantially maintained at a ground source.

4. The DAC of claim 3, further comprising second control circuitry configured to maintain the stability of the bipolar current signal.

5. The DAC of claim 1, wherein the first control circuitry comprises a servo circuit network coupled to a common node input of the subtractor circuity, the servo circuit being operative to maintain the first and the second current signals at substantially the same potential.

6. The DAC of claim 5, wherein the servo network comprises an amplifier having a first input coupled to a compensation network and to one of the first and second current signals, a second input coupled to the bipolar current signal and to another one of the first and second current signals, and an output coupled to the common node input of the subtractor circuitry and to an output of the compensation network.

7. The DAC of claim 1, wherein the first and second analog current signals are complementary.

8. The DAC of claim 1, wherein the digital-to-analog converter circuitry comprises one or more R-2R circuit networks, string digital-to-analog converters, or binary weighted current steered digital-to-analog converters.

9. The DAC of claim 1, wherein the digital-to-analog converter circuitry comprises a plurality of resistors and a plurality of capacitors in a precision resistor network.

10. The DAC of claim 1, where the first potential tracks a zero reference potential.

11. The DAC of claim 1, where the first potential is held at a zero reference potential.

12. A point-of-care diagnostic device comprising the DAC of claim 1.

13. The DAC of claim 1, wherein the subtractor circuit comprises a current mirror network.

14. A diagnostic system for performing electrochemical detection of a target analyte, the system comprising:

the DAC according to claim 1;

processor circuitry configured to receive the digital data, and to provide a digital setpoint value indicative of a reference signal to be applied to a counter electrode in electrical contact with the target analyte, wherein the binary analog signal of the DAC is indicative of the digital setpoint value; and

servoing loop circuitry configured to receive the binary analog signal and to apply, in response to the binary analog signal, a potential to the counter electrode.

15. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential;

wherein the DAC is configured to provide the bipolar current signal having the zero center point without calibration or trimming.

16. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential, at least one of the first and second analog current signals substantially maintained at a ground potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

17. The DAC of claim 16, further comprising second control circuitry configured to maintain the stability of the bipolar current signal.

18. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, the first control circuitry including a servo circuit network coupled to a common note input of the subtractor circuitry, the servo circuit network configured to modify the second potential so that the second potential equals the first potential.

19. The DAC of claim 18, wherein the servo network comprises an amplifier having a first input coupled to a compensation network and to one of the first and second current signals, a second input coupled to the bipolar current signal and to another one of the first and second current signals, and an output coupled to the common node input of the subtractor circuitry and to an output of the compensation network.

20. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential, the first and second analog current signals being complementary;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

21. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry including one or more R-2R circuit networks, string digital-to-analog converters, or binary weighted current steered digital-to-analog converters, the digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

22. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry including a plurality of resistors and a plurality of capacitors in a precision resistor network, the digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

23. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential that tracks a zero reference potential from a voltage source external to the DAC, and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

24. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential held at the zero reference potential from a voltage source external to the DAC, and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

25. A point-of-care diagnostic device comprising:

a digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising;

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

26. A precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising:

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry including a current mirror network configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential.

27. A diagnostic system for performing electrochemical detection of a target analyte, the system comprising:

a precision digital-to-analog converter (DAC) for converting digital data to a bipolar analog signal, comprising;

digital-to-analog converter circuitry configured to provide, responsive to digital input data, a first analog current signal having a first potential and a second analog current signal having a second potential;

subtractor circuitry configured to provide a bipolar current signal by subtracting the second analog current signal from the first analog current signal, the bipolar current signal having a zero center point; and

first control circuitry electrically coupled to the subtractor circuitry and to the digital-to-analog converter circuitry, and configured to modify the second potential so that the second potential equals the first potential;

processor circuitry configured to receive the digital data, and to provide a digital setpoint value indicative of a reference signal to be applied to a counter electrode in electrical contact with the target analyte, wherein the binary analog signal of the DAC is indicative of the digital setpoint value; and

servoing loop circuitry configured to receive the binary analog signal and to apply, in response to the binary analog signal, a potential to the counter electrode.