Sensor having ferrogel with magnetic particles

• US 9,737,244 B2
• Filed: 03/13/2013
• Issued: 08/22/2017
• Est. Priority Date: 03/13/2012
• Status: Active Grant

• Current Assignee: Purdue Research Foundation (Purdue University), Regents of The University of Minnesota (University of Minnesota)
• Original Assignee: Purdue Research Foundation (Purdue University), Regents of The University of Minnesota (University of Minnesota)
• Inventors: Ziaie, Babak, Siegel, Ronald A.
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US13/800,860
• Publication Number:
  US 20130245402A1
• Time in Patent Office: 1,623 Days
• Field of Search: None
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: G01N 27/72 by investigating magnetic variables

Abstract

A sensor for detecting a condition includes a hydrogel configured to change thickness or volume in response to the condition. Magnetic particles are arranged in the hydrogel so that a magnetic property of the hydrogel changes with changes of thickness or volume of the hydrogel. Some such sensors include a magnetic-field detector that measures the magnetic field of the hydrogel. Other such sensors include a device coil is arranged with respect to the hydrogel so that changes in the magnetic property modulate an electrical property of the sensor. A sensing system using such a sensor includes a reader spaced apart from the sensor and including a reader coil and a resonance detector coupled to the reader coil to detect a the resonant frequency of the sensor. Changes in the magnetic property detectably modulate the resonant frequency.

Claims

1. A sensor for detecting a condition, the sensor comprising:

a container;

a hydrogel arranged within the container and configured to change thickness or volume in response to the condition;

a plurality of magnetic particles arranged in the hydrogel so that a magnetic property of the hydrogel changes with changes of thickness or volume of the hydrogel; and

a device coil arranged within the container and arranged with respect to the hydrogel so that changes in the magnetic property modulate an electrical property of the sensor, wherein terminals of the device coil are open.

2. The sensor according to claim 1, wherein the hydrogel is arranged in a layer and the device coil is a planar coil arranged substantially parallel to the layer.

3. The sensor according to claim 1, further including a substrate and a membrane arranged to form a cavity in which the hydrogel is located and can swell or shrink, wherein the membrane is configured to allow passage of a fluid across the membrane and block passage of particles of a predetermined size that are suspended in the fluid.

4. The sensor according to claim 3, wherein the hydrogel, the substrate, and the membrane are configured so that the hydrogel does not completely fill the cavity.

5. The sensor according to claim 3, further including an insulating layer arranged between the hydrogel and the device coil.

6. The sensor according to claim 3, wherein the device coil is arranged in the cavity and is electrically insulated, and the hydrogel is patterned.

7. The sensor according to claim 3, wherein the device coil is arranged at least partly in the hydrogel.

8. The sensor according to claim 1, wherein the electrical property of the sensor is resonant frequency or inductance.

9. The sensor according to claim 1, wherein the magnetic property of the hydrogel is magnetic permeability.

10. The sensor according to claim 1, further including a surface on which the hydrogel is patterned as an array of columns.

11. The sensor according to claim 10, wherein each column in the array of columns is cylindrical.

12. The sensor according to claim 1, wherein the hydrogel is formed about the device coil.

13. The sensor according to claim 1, further including a substrate on or in which the device coil is formed, wherein the substrate includes polystyrene (PS), polymethylmethacrylate (PMMA), or polyimide (PI).

14. The sensor according to claim 1, wherein the condition is moisture, temperature, or pH.

15. The sensor according to claim 1, wherein the condition is presence of glucose.