Method and apparatus for providing data processing and control in a medical communication system

• US 9,737,249 B2
• Filed: 06/17/2015
• Issued: 08/22/2017
• Est. Priority Date: 05/14/2007
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories)
• Inventors: Hayter, Gary Alan, McGarraugh, Geoffrey V., Doniger, Kenneth J.
• Primary Examiner(s): SUGLO, JANET L
• Application Number:
  US14/741,457
• Publication Number:
  US 20150282742A1
• Time in Patent Office: 797 Days
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/0242 adapted to measure environmental factors, e.g. temperature, pollution
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61B 5/0008 Temperature signals
• CPC Class Codes: A61B 5/002 Monitoring the patient using a local or closed circuit, e.g. in a room or building A61B5/0017 takes precedence
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/1451 for interstitial fluid
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/4845 Toxicology, e.g. by detection of alcohol, drug or toxic products A61B5/4848 takes precedence
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 40/63 for local operation

Abstract

Methods and apparatus for providing data processing and control for use in a medical communication system are provided.

Claims

1. An apparatus, comprising:

a power supply;

an in vivo analyte sensor operatively coupled to the power supply to generate analyte sensor signals corresponding to a monitored analyte level in a biofluid when powered by the power supply;

a memory unit operatively coupled to the in vivo analyte sensor and the power supply to store the analyte sensor signals;

a data processing unit operatively coupled to the in vivo analyte sensor, the memory unit, and the power supply, the data processing unit generating data that corresponds to the monitored analyte level and a rate of change of the monitored analyte level from the analyte sensor signals, the generated data further including an indicator that one or more data packets of the generated data are corrupt; and

a data communication unit operatively coupled to the data processing unit, the data communication unit wirelessly communicating the generated data corresponding to the monitored analyte level and the determined rate of change of the monitored analyte level to a remote device using a wireless communication protocol, wherein the remote device is configured to use the indicator to determine a number of corrupt analyte values based on a comparison of the received signals to a predefined range.

2. The apparatus of claim 1, wherein the data communication unit is configured to determine that a predetermined number of valid analyte sensor signals is available when there are fewer than a predetermined number of invalid analyte sensor signals over a predetermined time period.

3. The apparatus of claim 2, wherein the invalid analyte sensor signals include a corrupt signal.

4. The apparatus of claim 2, wherein the invalid analyte sensor signals include a missing signal.

5. The apparatus of claim 1, wherein the biofluid includes one of interstitial fluid or dermal fluid.

6. The apparatus of claim 1, wherein the data communication unit wirelessly communicates data processing unit identification information with the generated data.

7. The apparatus of claim 1, wherein the in vivo analyte sensor comprises a plurality of electrodes including a working electrode having an analyte-responsive enzyme bonded to a polymer disposed on the working electrode.

8. The apparatus of claim 7, wherein the analyte responsive enzyme is chemically bonded to the polymer disposed on the working electrode.

9. The apparatus of claim 7, wherein the working electrode comprises a mediator crosslinked with the polymer.

10. The apparatus of claim 1, wherein the in vivo analyte sensor comprises a plurality of electrodes including a working electrode having a mediator bonded to a polymer disposed on the working electrode.

11. The apparatus of claim 1, wherein the data processing unit detects one or more states indicating when the in vivo analyte sensor is positioned in fluid contact with the biofluid.

12. The apparatus of claim 1, wherein the data processing unit detects one or more states indicating when the in vivo analyte sensor is removed from the biofluid.

13. The apparatus of claim 1, wherein the data processing unit generates an output signal when persistent low analyte sensor signals are detected.

14. The apparatus of claim 13, wherein the data communication unit communicates the generated output signal to the remote device using the wireless communication protocol.

15. The apparatus of claim 13, wherein the data processing unit detects the persistent low analyte sensor signals when the analyte sensor signals are below a predetermined threshold level continuously for a predefined time period.