Blood vessel occlusion

• US 9,737,307 B2
• Filed: 08/10/2015
• Issued: 08/22/2017
• Est. Priority Date: 02/05/2013
• Status: Expired due to Fees

• Current Assignee: ArtVentive Medical Group Inc
• Original Assignee: ArtVentive Medical Group Inc
• Inventors: Leopold, Andrew, Rudakov, Leon, Jensen, Kelly
• Primary Examiner(s): WEISBERG, AMY REGINA
• Application Number:
  US14/822,810
• Publication Number:
  US 20150342611A1
• Time in Patent Office: 743 Days
• Field of Search: 606191-200, 623 111- 135, 128831
• CPC Class Codes: A61B 17/12031 complete occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device

Abstract

An occlusion device delivery system can deliver an implant using a catheter. A distal section of the catheter has proximal and distal apertures extending through a wall of the catheter. The implant can be wound about the distal section and secured to the catheter via an engagement mechanism. The implant has a proximal segment that curves inwardly across the proximal aperture and a distal segment that curves inwardly across the distal aperture. The engagement mechanism engages the proximal and distal segments within their respective apertures to secure the implant to the catheter.

Claims

1. An occlusion device delivery system, comprising:

a catheter having a central axis and a lumen extending along the central axis between distal and proximal sections, the distal section having proximal and distal apertures extending through a wall of the catheter;

an engagement mechanism extending through the lumen; and

an implant supported on the catheter distal section and comprising a wire frame, wherein in an engaged configuration, the wire frame has (i) a proximal segment curving inwardly across the proximal aperture to be engaged with the engagement mechanism and terminating in a proximal terminal end tab having an increased cross-section relative to a first adjacent section of the wire frame, the proximal terminal end tab being positioned outside of the proximal aperture and (ii) a distal segment curving inwardly across the distal aperture to be engaged with the engagement mechanism and terminating in a distal terminal end tab having an increased cross-section relative to a second adjacent section of the wire frame, the distal terminal end tab being positioned outside of the distal aperture.

2. The system of claim 1, wherein the engagement mechanism comprises an elongate member positioned radially between the proximal segment and the catheter wall to engage the proximal segment.

3. The system of claim 2, wherein the elongate member is positioned radially between the distal segment and the catheter wall to engage the distal segment.

4. The system of claim 1, wherein the proximal segment comprises a reduced cross-sectional segment that is configured to extend within the proximal aperture in the engaged configuration.

5. The system of claim 1, wherein the distal segment comprises a reduced cross-sectional segment that is configured to extend within the distal aperture in the engaged configuration.

6. The system of claim 5, wherein the reduced cross-sectional segment comprises a distal notch having a first longitudinal length, the distal aperture having a distal aperture length extending transverse to the catheter central axis, the first longitudinal length being substantially equal to the distal aperture length.

7. The system of claim 1, wherein the proximal and distal segments extend across the lumen over a distance that is less than a diameter of the lumen.

8. The system of claim 1, wherein the engagement mechanism comprises an elongate member, and wherein upon proximal withdrawal of the elongate member through the catheter lumen, the elongate member is configured to disengage and radially release the distal segment from the distal aperture.

9. The system of claim 1, wherein the engagement mechanism comprises a wire.

10. The system of claim 1, wherein the engagement mechanism comprises first and second elongate members.

11. The system of claim 1, wherein the proximal and distal apertures comprise slots that are transverse to an axis of the lumen.

12. The system of claim 1, wherein the proximal segment comprises a proximal elbow at which the implant diverges from a helical path.

13. The system of claim 1, wherein the distal segment comprises a distal elbow at which the implant diverges from a helical path.

14. The system of claim 1, wherein the wire frame changes to a smaller radius of curvature along the proximal segment and the distal segment from an intermediate portion of the implant extending between the proximal and distal segments.

15. The system of claim 1, wherein the wire frame comprises a helical frame having a single-wire, flattened cross section.

16. An occlusion device delivery system, comprising:

a catheter having a central axis, a lumen extending therethrough, and proximal and distal sidewall apertures extending into the lumen;

an engagement mechanism disposed within the lumen; and

an implant configured to be secured to the catheter via the engagement mechanism, the implant comprising a wire frame having first and second end segments, the first end segment comprising a first tab having an increased cross-section relative to a first adjacent section of the wire frame, the second end segment comprises a second tab having an increased cross-section relative to a second adjacent section of the wire frame, wherein in an engaged configuration, the first and second end segments extend within the proximal and distal sidewall apertures and the implant bends inwardly from a helical path toward the central axis at the first and second end segments and first and second tabs of each of the first and second end segments are positioned outside of the proximal and distal sidewall apertures when engaged by the engagement mechanism, the engagement mechanism extending between a sidewall of the catheter and the first and second end segments to radially restrain the first end segment within the proximal sidewall aperture and the second end segment within the distal sidewall aperture, the engagement mechanism being movable to disengage from the first and second end segments to permit expansion of the implant from the engaged configuration.

17. The system of claim 16, wherein the engagement mechanism comprises a wire, and upon proximal withdrawal of the engagement mechanism through the catheter lumen, the engagement mechanism is configured to disengage and radially release the second end segment from the distal sidewall aperture.

18. The system of claim 17, wherein, upon continued proximal withdrawal of the engagement mechanism, the engagement mechanism is configured to disengage and radially release the first end segment from the proximal sidewall aperture.

19. The system of claim 16, wherein the engagement mechanism comprises first and second wires, the first wire being coupled to a first handle and the second wire being coupled to a second handle, the first and second handles being movable to cause disengagement of the first and second end segments of the implant.

20. The system of claim 16, wherein the first end segment comprises a proximal elbow at a first end thereof at which the implant diverges from a helical path.

21. The system of claim 16, wherein the second end segment comprises a distal elbow at a first end thereof at which the implant diverges from a helical path.

22. The system of claim 16, wherein the first tab is positioned at the first end and the second tab is positioned at the second end.

23. The system of claim 16, wherein the first and second end segments comprise respective first and second notches, and wherein the first tab forms part of the first notch and the second tab forms part of the second notch.

24. The system of claim 23, wherein the first and second notches have respective first and second longitudinal lengths, the proximal and distal sidewall apertures having respective proximal and distal aperture lengths extending transverse to the catheter central axis, the first and second longitudinal lengths being substantially equal to the respective proximal and distal aperture lengths.

25. The system of claim 16, wherein the wire frame comprises a rectangular cross section.

26. An occlusion device delivery system, comprising:

a catheter having a central axis, a lumen extending therethrough, and proximal and distal sidewall apertures extending into the lumen;

an engagement mechanism disposed within the lumen; and

an implant configured to be secured to the catheter via the engagement mechanism, the implant comprising first and second end segments, the first end segment comprising a first tab having an increased cross-section relative to a first adjacent section of the first end segment,

wherein in an engaged configuration, the first end segment extends within the proximal sidewall aperture and the first tab is positioned outside of the proximal sidewall aperture while the engagement mechanism extends between a sidewall of the catheter and the first end segment to radially restrain the first end segment within the proximal sidewall aperture.

27. The system of claim 26, wherein the second end segment comprises a second tab having an increased cross-section relative to a second adjacent section of the second end segment, wherein in the engaged configuration, the second end segment extends within the distal sidewall aperture and the second tab is positioned outside of the distal sidewall aperture while the engagement mechanism extends between the sidewall of the catheter and the second end segment to radially restrain the second end segment within the distal sidewall aperture.