Auto-injector

• US 9,737,663 B2
• Filed: 12/21/2011
• Issued: 08/22/2017
• Est. Priority Date: 12/21/2010
• Status: Expired due to Fees

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Jennings, Douglas, Kemp, Thomas, Ekman, Matthew
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): Darb, Hamza
• Application Number:
  US13/994,885
• Publication Number:
  US 20130281929A1
• Time in Patent Office: 2,071 Days
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/6018 providing set-up signals for the apparatus configuration
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2205/6072 Bar codes
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/20 Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically A61M5/142 , A61M5/46 take precedence; hypodermic projectiles F42B12/54
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

The invention relates to a compression connection means for an auto-injector (A), wherein the compression connection means adapted to attach a front-end device of the auto-injector (A) to a back-end device of the auto-injector (A) comprises of an annular mounting sleeve that is axially displaceable parallel to a longitudinal axis (X) between a locked position (L) and an unlocked position, a mounting sleeve spring biasing the mounting sleeve towards a locked position (L), at least one latch arm connected to one of either the front-end device or the back-end device, wherein the latch arm is deflectable in a radial direction, wherein the mounting sleeve in the locked position (L) is arranged to prevent the radial deflection of the latch arm and wherein the mounting sleeve in the unlocked position allows for a radial deflection of the latch arm, so as to allow the latch arm to be deflected on assembly or disassembly of the front-end device to the back-end device and to latch to or unlatch from the other of the front-end device or the back-end device.

Claims

1. A front-end device of an auto-injector (A) for administering a dose of a liquid medicament, wherein the front-end device is adapted to receive a syringe with an injection needle and a barrel containing the dose of the medicament and comprises

a tubular outer sleeve,

a compression connector for attaching the front-end device to a back-end device of the auto-injector (A), wherein the compression connector comprises:

an annular mounting sleeve that is axially displaceable parallel to a longitudinal axis (X) between a locked position (L) and an unlocked position,

a mounting sleeve spring biasing the mounting sleeve towards the locked position (L),

at least one latch arm connected to the back-end device,

wherein the at least one latch arm is deflectable in a radial direction, wherein the mounting sleeve in the locked position (L) is arranged to prevent a radial deflection of the at least one latch arm and wherein, in response to axially displacing the annular mounting sleeve to the unlocked position, the mounting sleeve in the unlocked position allows for the radial deflection of the latch arm, so as to allow the latch arm to be deflected on assembly or disassembly of the front-end device to the back-end device and to latch to or unlatch from the front-end device; and

wherein the compression connector is configured to transition from the locked position (L) to the unlocked position when the annular mounting sleeve is displaced with respect to the tubular outer sleeve against a biasing force of the mounting sleeve spring in a proximal direction to the locked position (L).

2. The front-end device according to claim 1, wherein a syringe retainer adapted to receive the pre-filled syringe is slidably arranged with respect to the outer sleeve, wherein the syringe retainer is arranged to be translated between a first position (I) and a second position (II) and wherein the syringe retainer comprises at least one flexible arm arranged to latch to the outer sleeve to releasably retain the syringe retainer in the first position (I).

3. The front-end device according to claim 2, wherein a needle shroud adapted to rest on a skin of a patient is slidably arranged with respect to the outer sleeve, wherein the needle shroud is arranged to be translated between an advanced position (PA) and a retracted position (PR) and wherein the needle shroud comprises an extension arm that is arranged to engage a release ramp on the syringe retainer to de-latch the syringe retainer from the outer sleeve in the retracted position (PR).

4. An auto-injector (A) for administering a dose of a liquid medicament, comprising:

a front-end device; and

a reusable back-end device comprising;

a housing,

a plunger connected to or adapted to engage a stopper providing a fluid tight seal for a distal end of the barrel,

a motor for displacing the plunger connected to the stopper; and

a compression connector for attaching the front-end device to the back-end device, the compression connector comprising;

an annular mounting sleeve that is axially displaceable parallel to a longitudinal axis (X) between a locked position (L) and an unlocked position,

a mounting sleeve spring biasing the mounting sleeve towards the locked position (L),

at least one latch arm connected to the back-end device,

wherein the at least one latch arm is deflectable in a radial direction, wherein the mounting sleeve in the locked position (L) is arranged to prevent a radial deflection of the at least one latch arm and wherein, in response to axially displacing the annular mounting sleeve to the unlocked position, the mounting sleeve in the unlocked position allows for the radial deflection of the latch arm, so as to allow the latch arm to be deflected on assembly or disassembly of the front-end device to the back-end device and to latch to or unlatch from the front-end device; and

wherein the compression connector is configured to transition from the locked position (L) to the unlocked position when the annular mounting sleeve is displaced with respect to a tubular outer sleeve against a biasing force of the mounting sleeve spring in a proximal direction to the locked position (L).

5. The auto-injector (A) according to claim 4, wherein a tubular cover is connected to a needle cap covering the injection needle of a syringe, wherein the tubular cover is arranged to facilitate removal of the needle cap when the syringe is retained within the front-end device.

6. The auto-injector (A) according to claim 4, wherein a needle shroud adapted to rest on a skin of a patient is slidably arranged with respect to the outer sleeve, wherein the needle shroud is arranged to be translated between an advanced position (PA) and a retracted position (PR), wherein an interlock switch is arranged to detect the position (PA, PR) of the needle shroud.

7. The auto-injector (A) according to claim 4, wherein the back-end device comprises a sensor unit for detecting actual parameters of the injection, a memory unit for storing user related data and/or specification parameters and a feedback provider to a user of the auto-injector (A).

8. The auto-injector (A) according to claim 4, wherein the back-end device further comprises an encoder sensor capable of determining a position of the plunger.

9. The auto-injector (A) according to claim 4, wherein at least one radially inwards projecting retaining projection is formed to an inner surface of a syringe retainer, the retaining projection adapted to frictionally engage the barrel of a syringe.