Method and system for assisting a wire guide to cross occluded ducts

• US 9,743,980 B2
• Filed: 02/24/2010
• Issued: 08/29/2017
• Est. Priority Date: 02/24/2010
• Status: Active Grant

• Current Assignee: SafePass Vascular Ltd. (Nordson Corporation)
• Original Assignee: SafePass Vascular Ltd. (Nordson Corporation)
• Inventors: Diamant, Valery, Chernenko, Vladimir, Lerner, Marat, Ivanova, Ludmila, Dutov, Alexey, Yasko, Nadezda
• Primary Examiner(s): Peffley, Michael
• Assistant Examiner(s): GOOD, SAMANTHA M
• Application Number:
  US12/711,755
• Publication Number:
  US 20110208185A1
• Time in Patent Office: 2,743 Days
• Field of Search: 606 41, 606 45- 50
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22094 for crossing total occlusions, i.e. piercing
• CPC Class Codes: A61B 2018/00178 Electrical connectors
• CPC Class Codes: A61B 2018/00422 Angioplasty
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/162 located on the probe body

Abstract

A method and a system for assisting a wire guide to cross obstructed ducts in mammalian body are described. The method and system is based on applying pulsed energy to occlusion obstructing the duct. The pulsed energy is applied by means of an auxiliary probe. The auxiliary probe is relatively displaceable with respect to the wire guide along a lumen provided within the probe. The distal region of the probe is provided with enhanced flexibility comparing with the reminder portion of the probe.

Claims

1. A system (10) for assisting a wire guide (32) to cross a duct (44) in a mammalian body when the duct is obstructed by an at least partially inorganic occlusion (46), said system being suitable to at least partially disrupt the occlusion (46) by supplying immediately to the occlusion low frequency, high voltage pulses of energy, said system comprising:

a probe (12) insertable in the duct (44) in the mammalian body, said probe (12) having a body portion with a distal end and a proximal end, said probe (12) having a working head (14) fitted with a couple of electrodes, one of the electrodes being a potential high voltage electrode (78) and a second of the electrodes being a ground electrode (80), wherein said working head (14) is coupled to the distal end of the body portion and said probe (12) has a first lumen (66) for receiving therein a miniature coaxial cable (62);

a control unit (18) for generation and controlling of pulses of energy supplied to the couple of electrodes (78, 80) either as discrete, one time pulses or as series of repeating pulses;

a power cable (16) electrically connecting the probe (12) to the control unit (18), said power cable (16) suitable for supplying said pulses of energy to the potential high voltage electrode (78) and to the ground electrode (80) via the miniature coaxial cable (62) such that an electrical breakdown discharge can be provoked between the potential high voltage electrode (78) and the ground electrode (80);

said miniature coaxial cable (62) comprising a potential electrode (622) and a shield electrode (620), said power cable (16) comprising a potential electrode and a shield electrode, wherein the potential electrode (622) of the miniature coaxial cable (62) is electrically connected to the potential electrode of the power cable (16) and the shield electrode (620) of the miniature coaxial cable (62) is electrically connected to the shield electrode of the power cable (16), in which the shield electrode (620) of the miniature coaxial cable (62) is electrically connected with the ground electrode (80) of the working head (14) and wherein the potential electrode (622) of the miniature coaxial cable (620) is electrically connected with the potential high voltage electrode (78) of the working head (14);

wherein the probe (12) is provided with a lateral opening (30) for introducing the wire guide (32) therethrough to allow relative displacement between the wire guide (32) and the probe (12),

and the body portion of the probe (12) comprises a region (28), which is located adjacent the working head (14), said region (28) having enhanced flexibility in comparison with a remainder of the body portion,

wherein the first lumen (66) is longitudinally extending through the body portion except of the region (28) and said probe is provided with a second lumen (72, 90) for receiving the wire guide (32) therein, the second lumen (72) extending along the region (28) and along the working head (14), wherein said second lumen (72) being more flexible than the first lumen (66),

wherein said potential high voltage electrode (78) and said ground electrode (80) is configured as a tubular body, wherein the high voltage electrode (78) is disposed concentrically with respect to the ground electrode (80) and is electrically insulated therefrom and wherein the wire guide (32) is electrically insulated from the potential high voltage electrode (78) and from the ground electrode (80).

2. A system of claim 1, in which said control unit (18) is capable generate pulses of electrical energy defined by the following parameters:

frequency 1-5 Hz, duration of a single pulse not more than 5000 nanoseconds, pulse rise time less than 50 nanoseconds, pulse energy 0.01-1.0 Joule, pulse amplitude 3-15 kV.

3. A system of claim 1, comprising a coupler (C) for detachable connecting the probe (12) with the power cable (16), said coupler is provided with a male portion (24) associated with the probe (12) and with a female portion (26) associated with the power cable (16).

4. A system of claim 1, in which said power cable (16) is a high voltage coaxial cable.

5. A system of claim 1, in which the potential high voltage electrode (78) and the ground electrode (80) are configured as respective outer and inner cylindrical bushing, wherein said potential high voltage electrode (78) is coaxial with the ground electrode (80).

6. A system of claim 5, in which a distal end of the potential high voltage electrode (78) is not flush with a distal end of the ground electrode (80).

7. A system of claim 6, in which the distal end of the ground electrode (80) is buried within the working head (14) with respect to the distal end of the potential high voltage electrode (78).

8. A system of claim 1, in which the probe (12) is provided with an outside cover (64) and with at least one reinforcing element (74) such that the reinforcing element is affixed to an inwardly facing surface of the outside cover (64).

9. A system of claim 1, in which the second lumen (90) comprises a plastic tube and the first lumen (66) comprises a stainless steel coil.

10. A system of claim 1, in which the first lumen (66) and the second lumen (90) comprises a stainless steel coil.

11. A system of claim 10, in which the shield electrode (620) of the miniature coaxial cable (62) is electrically connected to the second lumen (90).

12. A system of claim 11, in which the probe (12) is provided with an additional grounding electrode (92), which is electrically connected with the shield electrode of the power cable (16) and with the second lumen (90).

13. A system of claim 12, in which the probe is provided with a coupling member (110) for coupling between the region (28) and remainder portion of the probe (12).

14. A system of claim 13, in which the coupling member (110) is configured as a muff made of a material selected from the group consisting of polyurethane, polyester and polyimide.