Axial lengthening thrombus capture system

• US 9,744,024 B2
• Filed: 02/08/2017
• Issued: 08/29/2017
• Est. Priority Date: 08/06/2015
• Status: Active Grant

• Current Assignee: Vascular Medcure Incorporated (Medtronic Plc)
• Original Assignee: KP Medcure, Inc.
• Inventors: Nguyen, Thanh Van, Nguyen, Duy, Ngo, Tung Hoang
• Primary Examiner(s): Woo, Julian W
• Application Number:
  US15/428,076
• Publication Number:
  US 20170143359A1
• Time in Patent Office: 202 Days
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 17/32075 Pullback cutting; combined forward and pullback cutting, e.g. with cutters at both sides of the plaque
• CPC Class Codes: A61B 17/320758 with a rotating cutting instrument, e.g. motor driven A61B17/320725, A61B17/32075 and A61B17/320783 take precedence; for removing intra-ocular material A61F9/00763; endoscopic rotatable cutting instruments A61B17/32002
• CPC Class Codes: A61B 2017/00867 shape memory effect for prostheses A61F2210/0014
• CPC Class Codes: A61B 2017/00871 polymeric
• CPC Class Codes: A61B 2017/00938 hydrophobic
• CPC Class Codes: A61B 2017/00942 hydrophilic
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/22038 with a guide wire
• CPC Class Codes: A61B 2017/22079 with suction of debris
• CPC Class Codes: A61B 2017/22081 Treatment of vulnerable plaque
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61B 2017/2217 single wire changing shape to a gripping configuration
• CPC Class Codes: A61B 2017/320052 Guides for cutting instruments by marking A61B2090/395
• CPC Class Codes: A61B 2017/320716 comprising means for preventing embolism by dislodged material
• CPC Class Codes: A61B 2017/320775 Morcellators, impeller or propeller like means
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2002/016 : made from wire-like elements
• CPC Class Codes: A61M 1/79 : Filters for solid matter specially adapted for dental use A61C17/065

Abstract

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

Claims

1. A clot capture system, comprising:

an outer sheath comprising a central lumen;

a dual lumen shaft configured to be positioned within the central lumen of the outer sheath;

an inner pusher configured to be positioned within a first lumen of the dual lumen shaft;

an anchor pusher configured to be positioned within a second lumen of the dual lumen shaft;

an anchor coupled to the anchor pusher;

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide attached to a portion of the opening,

wherein the shape memory tubular body and the anchor are compressed in a first configuration,

wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide are radially expanded but the second end and a majority of the shape memory tubular body remains compressed within the first lumen of the dual lumen shaft and the shape memory tubular body has a first expanded axial length with a first cross-section, wherein the first cross-section is substantially similar to a cross-section of the capture guide,

wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein the shape memory tubular body encapsulates the anchor in the third configuration.

2. The clot capture system of claim 1, comprising two anchors.

3. The clot capture system of claim 2, wherein the two anchors have a central longitudinal axis that is coaxial.

4. The clot capture system of claim 1, comprising three anchors.

5. The clot capture system of claim 1, wherein the cross-section of the shape memory tubular body is round.

6. The clot capture system of claim 1, wherein the anchor comprises nitinol.

7. The clot capture system of claim 1, wherein the anchor forms an angle with the anchor pusher when expanded, wherein the angle is approximately 90 degrees.

8. The clot capture system of claim 1, wherein the anchor forms an angle with the anchor pusher when expanded, wherein the angle is approximately 45 degrees.

9. The clot capture system of claim 1, wherein the anchor forms an angle with the anchor pusher when expanded, wherein the angle is between 5 degrees and 135 degrees.

10. The clot capture system of claim 1, wherein a diameter of the anchor is less than a diameter of the shape memory tubular body when expanded.

11. The clot capture system of claim 1, wherein a portion of the anchor pusher is crescent shaped.

12. The clot capture system of claim 1, wherein the capture guide comprises nitinol.

13. The clot capture system of claim 1, wherein the capture guide comprises a central longitudinal axis and wherein the dual lumen shaft is offset from the central longitudinal axis.

14. The clot capture system of claim 1, wherein the second end of the shape memory tubular body is coupled to the inner pusher.

15. A method of using a clot capture system, comprising:

positioning the system of claim 1 near a blood clot;

transforming the shape memory tubular body to the second configuration;

expanding the anchor; and

transforming the shape memory tubular body to the third configuration to encapsulate the anchor.

16. The method of claim 15, wherein expanding the anchor comprises securing the anchor within the blood clot.

17. The method of claim 15, wherein transforming the shape memory tubular body to the third configuration to encapsulate the anchor further comprises encapsulating the blood clot.

18. The method of claim 15, wherein the blood clot is a neurological blood clot.

19. A clot capture system, comprising:

an inner pusher element;

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an opening and a capture guide attached to at least a portion of the opening, the second end coupled to the inner pusher element,

wherein the shape memory tubular body and the capture guide are compressed in a first configuration,

wherein the shape memory tubular body is transformable to a second configuration in which the first end and the capture guide are radially expanded but the second end and a majority of the shape memory tubular body remains compressed and the shape memory tubular body has a first expanded axial length with a first cross-section, wherein the first cross-section is substantially similar to a cross-section of the capture guide,

wherein the shape memory tubular body is transformable to a third configuration in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length.

20. The clot capture system of claim 19, wherein the capture guide forms a continuous loop.

21. The clot capture system of claim 19, wherein the capture guide forms a non-continuous loop.

22. A method of using a clot capture system, comprising:

positioning the system of claim 19 near a blood clot in the first configuration;

transforming the shape memory tubular body to the second configuration; and

transforming the shape memory tubular body to the third configuration to encapsulate the blood clot.

23. The method of claim 22, wherein the blood clot is within the central nervous system.

24. A clot capture system, comprising:

a first tubular member comprising a central lumen;

a second tubular member;

a plurality of axially spaced-apart anchors extending radially outwardly from the first tubular member or the second tubular member; and

a shape memory tubular body comprising a first end, a second end, and an axial length therebetween, the first end having an end opening, the second end attached to the second tubular member,

wherein at least part of the shape memory tubular body is compressed within the central lumen of the first tubular member in a first delivery configuration,

wherein the shape memory tubular body is transformable to a second configuration in which the first end is radially expanded while the second end and a majority of the shape memory tubular body remains compressed within the central lumen of the first tubular member and the second end is positioned proximal to the first end and the shape memory tubular body has a first expanded axial length,

wherein the shape memory tubular body is transformable to a third configuration via movement of the first tubular member with respect to the second tubular member in which the shape memory tubular body has a second expanded axial length greater than the first expanded axial length, wherein a width of the shape memory tubular body along the second expanded axial length is substantially the same as a width of the shape memory tubular body along the first expanded axial length.