Syringe pump and related method

• US 9,744,300 B2
• Filed: 03/15/2013
• Issued: 08/29/2017
• Est. Priority Date: 12/21/2011
• Status: Active Grant

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Kamen, Dean, Gray, Larry B., Bodwell, Jesse T., Kerwin, John M., van der Merwe, Dirk A., Fichera, Stephen L., Thurber, Jonathan R., Desch, Martin D.
• Primary Examiner(s): Gilbert, Andrew
• Application Number:
  US13/833,432
• Publication Number:
  US 20130281965A1
• Time in Patent Office: 1,628 Days
• CPC Class Codes: A61M 2205/103 rotating
• CPC Class Codes: A61M 2205/16 with back-up system in case of failure
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3365 Rotational speed
• CPC Class Codes: A61M 2205/3584 using modem, internet or bluetooth
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/587 Lighting arrangements
• CPC Class Codes: A61M 2205/6054 Magnetic identification systems
• CPC Class Codes: A61M 2205/8206 battery-operated
• CPC Class Codes: A61M 5/1408 in parallel, e.g. manifolds, sequencing valves access sites A61M39/02; tube connectors A61M39/10
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14236 Screw, impeller or centrifugal type pumps
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/16827 : controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/172 : electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 40/63 : for local operation
• CPC Class Codes: G16H 40/67 : for remote operation

Abstract

A pump for administering an agent to a patient includes a housing, a syringe seat, and a bumper. The syringe seat is coupled to the housing. The bumper is coupled to the housing adjacent to the syringe seat.

Claims

1. A syringe pump comprising:

a housing;

a syringe seat coupled to the housing, the syringe seat configured to retain a syringe having a barrel and a plunger disposed within the barrel;

a lead screw rotatable within the housing;

a motor coupled to the lead screw configured to rotate the lead screw;

a sliding block assembly configured for engaging with the lead screw to move along the lead screw in accordance with rotation of the lead screw, wherein the sliding block assembly comprises;

a half-nut housing having a lead screw void configured to receive the lead screw therewithin;

a half nut disposed within the half-nut housing and having half nut threads at an end adjacent to the lead screw void, the half nut is slideable between an engagement position whereby the half nut threads engage with threads of the lead screw thereby creating slack and a disengagement position whereby the half nut threads are disengaged from the threads of the lead screw, wherein the half nut includes a cam follower surface and a half nut slot; and

a barrel cam disposed within the half-nut housing and configured to engage with the cam follower surface, the barrel cam includes a pin configured to fit within the half nut slot, wherein the barrel cam is configured to rotate between a first position and a second position to actuate the half-nut between the engagement position and the disengagement position, respectively;

a plunger head assembly coupled to the sliding block assembly and configured to drive the plunger of the syringe into the barrel of the syringe, the plunger head assembly having a force sensor operatively coupled to the plunger of the syringe to measure a force of the plunger head assembly on the plunger of the syringe; and

a processor operatively coupled to the motor and configured to control the rotation of the motor to thereby control actuation of the plunger head assembly, the processor is also operatively coupled to the force sensor to receive a measured force therefrom, wherein the processor is configured to;

receive a target flow rate of the syringe loaded on the syringe pump;

determine a therapy actuation speed corresponding to the target flow rate;

command the motor to actuate the plunger of the syringe out of the barrel at a first predetermined speed until the force sensor coupled to the plunger measures a force that is less than a first predetermined force threshold;

command the motor to actuate the plunger of the syringe into the barrel at a second predetermined speed greater than the therapy actuation speed until the force sensor coupled to the plunger measures a force that exceeds a second predetermined threshold; and

command the motor to actuate the plunger of the syringe into the barrel at the therapy actuation speed.

2. The syringe pump according to claim 1, wherein the therapy actuation speed corresponds to the target flow rate when there is no slack in the syringe pump or the syringe.

3. The syringe pump according to claim 1, wherein the processor is further configured to estimate a volume discharged starting from the position of the plunger when the second predetermined threshold was exceeded.

4. The syringe pump according to claim 3, wherein the processor is further configured to stop the syringe pump when the estimated volume discharged is equal to or exceeds a target delivery volume.

5. The syringe pump according to claim 1, further comprising a transceiver, wherein the processor is configured to communicate via the transceiver with a monitoring client.

6. The syringe pump according to claim 1, further comprising

a bumper coupled to the housing adjacent to the syringe seat, wherein the bumper at least partially surrounds a corner of the syringe seat.

7. The syringe pump according to claim 1, further comprising:

a rotary position sensor operatively coupled to at least one of the motor and the lead screw to provide a rotation signal; and

a linear position sensor operatively coupled to the sliding block assembly and configured to provide a linear position signal, wherein;

the motor has an integral motor rotation sensor configured to provide a motor rotation signal,

the processor is configured to control rotation of the motor,

the processor operatively receives the motor rotation signal from the integral motor rotation sensor of the motor, the rotation signal from the rotary position sensor, and the linear position signal from the linear position sensor, and

the processor is configured to determine if a discrepancy exists among the motor rotation signal, the rotation signal, and the linear position signal.

8. The syringe pump according to claim 7, wherein the rotary position sensor is operatively coupled to the motor.

9. The syringe pump according to claim 7, wherein the rotary position sensor is operatively coupled to the lead screw.

10. The syringe pump according to claim 7, wherein the processor is further configured to continue an infusion treatment by ignoring an inoperative one of the integral motor rotation sensor, the rotary position sensor, and a linear position sensor.

11. The syringe pump according to claim 7, wherein the rotary position sensor is a magnetic encoder sensor.

12. The syringe pump according to claim 7, wherein the syringe pump is configured to communicate with a monitoring client.

13. The syringe pump according to claim 1, further

a retaining finger pivotally coupled to the housing, wherein the retaining finger is configured to rotate toward the syringe disposed within the syringe seat to retain the syringe.

14. The syringe pump according to claim 13, wherein the syringe pump is configured to communicate with a monitoring client.

15. A syringe pump comprising:

a housing;

a syringe seat coupled to the housing, the syringe seat configured to retain a syringe having a barrel and a plunger disposed within the barrel;

a lead screw rotatable within the housing;

a motor coupled to the lead screw configured to rotate the lead screw;

a sliding block assembly configured for engaging with the lead screw to move along the lead screw in accordance with rotation of the lead screw, wherein the sliding block assembly comprises;

a half-nut housing having a lead screw void configured to receive the lead screw therewithin;

a half nut disposed within the half-nut housing and having half nut threads at an end adjacent to the lead screw void, the half nut is slideable between an engagement position whereby the half nut threads engage with threads of the lead screw thereby creating slack and a disengagement position whereby the half nut threads are disengaged from the threads of the lead screw, wherein the half nut includes a cam follower surface and a half nut slot; and

a barrel cam disposed within the half-nut housing and configured to engage with the cam follower surface, the barrel cam includes a pin configured to fit within the half nut slot, wherein the barrel cam is configured to rotate between a first position and a second position to actuate the half nut between the engagement position and the disengagement position, respectively;

a plunger head assembly coupled to the sliding block assembly and configured to drive the plunger of the syringe into the barrel of the syringe, the plunger head assembly having a force sensor operatively coupled to the plunger of the syringe to measure a force of the plunger head assembly on the plunger of the syringe; and

a processor operatively coupled to the motor and configured to control the rotation of the motor to thereby control actuation of the plunger head assembly, the processor is also operatively coupled to the force sensor to receive a measured force therefrom, wherein the processor is configured to;

receive a target flow rate of the syringe loaded on the syringe pump;

determine a therapy actuation speed corresponding to the target flow rate;

command the motor to actuate the plunger of the syringe out of the barrel at a first predetermined speed until the force sensor coupled to the plunger measures a force that is less than a first predetermined force threshold or the plunger travels out of the barrel by a first predetermined distance;

command the motor to actuate the plunger of the syringe into the barrel at a second predetermined speed greater than the therapy actuation speed until the force sensor coupled to the plunger measures a force that exceeds a second predetermined threshold or the plunger travels into the barrel by a second predetermined distance; and

command the motor to actuate the plunger of the syringe into the barrel at the therapy actuation speed.

16. The syringe pump according to claim 15, wherein the therapy actuation speed corresponds to the target flow rate when there is no slack in the syringe pump or the syringe.

17. The syringe pump according to claim 15, wherein the processor is further configured to estimate a volume discharged starting from the position of the plunger when the second predetermined threshold was exceeded.

18. The syringe pump according to claim 17, wherein the processor is further configured to stop the syringe pump when the estimated volume discharged is equal to or exceeds a target delivery volume.

19. The syringe pump according to claim 15, wherein the processor is further configured issue an alarm if the plunger traveled into the barrel by the second predetermined distance without the force sensor measuring a force that exceeds the second predetermined threshold.

20. The syringe pump according to claim 15, further comprising a transceiver, wherein the processor is configured to communicate via the transceiver with a monitoring client.

21. A method for removing the effects of slack in a syringe pump having a syringe loaded on the syringe pump, the syringe having a barrel and a plunger disposed within the barrel, the method comprising:

coupling a sliding block assembly with lead screw, the sliding block assembly comprising;

a half-nut housing having a lead screw void configured to receive the lead screw therewithin;

a half nut disposed within the half-nut housing and having half nut threads at an end adjacent to the lead screw void, the half nut is slideable between an engagement position whereby the half nut threads engage with threads of the lead screw thereby creating the slack and a disengagement position whereby the half nut threads are disengaged from the threads of the lead screw, wherein the half nut includes a cam follower surface and a half nut slot; and

a barrel cam disposed within the half-nut housing and configured to engage with the cam follower surface, the barrel cam includes a pin configured to fit within the half nut slot, wherein the barrel cam is configured to rotate between a first position and a second position to actuate the half-nut between the engagement position and the disengagement position, respectively;

receiving a target flow rate of the syringe loaded on the syringe pump;

determining a therapy actuation speed corresponding to the target flow rate;

actuating the plunger of the syringe out of the barrel by rotating the lead screw at a first predetermined speed until a force sensor coupled to the plunger measures a force that is less than a first predetermined force threshold;

actuating the plunger of the syringe into the barrel by rotating the lead screw at a second predetermined speed greater than the therapy actuation speed until the force sensor coupled to the plunger measures a force that exceeds a second predetermined threshold; and

actuating the plunger of the syringe into the barrel by rotating the lead screw at the therapy actuation speed.

22. The method according to claim 21, wherein the therapy actuation speed corresponds to the target flow rate when there is no slack in the syringe pump or the syringe.

23. The method according to claim 21, further comprising estimating a volume discharged starting from the position of the plunger when the second predetermined threshold was exceeded.

24. The method according to claim 23, further comprising stopping the syringe pump when the estimated volume discharged is equal to or exceeds a target delivery volume.

25. The method according to claim 21, further comprising communicating an actual speed of the plunger to a monitoring client.

26. A method for removing the effects of slack in a syringe pump having a syringe loaded on the syringe pump, the syringe having a barrel and a plunger disposed within the barrel, the method comprising:

coupling a sliding block assembly with lead screw, the sliding block assembly comprising;

a half-nut housing having a lead screw void configured to receive the lead screw therewithin;

a half nut disposed within the half-nut housing and having half nut threads at an end adjacent to the lead screw void, the half nut is slideable between an engagement position whereby the half nut threads engage with threads of the lead screw thereby creating the slack and a disengagement position whereby the half nut threads are disengaged from the threads of the lead screw, wherein the half nut includes a cam follower surface and a half nut slot; and

a barrel cam disposed within the half-nut housing and configured to engage with the cam follower surface, the barrel cam includes a pin configured to fit within the half nut slot, wherein the barrel cam is configured to rotate between a first position and a second position to actuate the half-nut between the engagement position and the disengagement position, respectively;

receiving a target flow rate of the syringe loaded on the syringe pump;

determining a therapy actuation speed corresponding to the target flow rate;

actuating the plunger of the syringe out of the barrel at a first predetermined speed by rotating the lead screw until a force sensor coupled to the plunger measures a force that is less than a first predetermined force threshold or the plunger travels out of the barrel by a first predetermined distance;

actuating the plunger of the syringe into the barrel at a second predetermined speed greater than the therapy actuation speed by rotating the lead screw until the force sensor coupled to the plunger measures a force that exceeds a second predetermined threshold or the plunger travels into the barrel by a second predetermined distance; and

actuating the plunger of the syringe into the barrel at the therapy actuation speed by rotating the lead screw.

27. The method according to claim 26, wherein the therapy actuation speed corresponds to the target flow rate when there is no slack in the syringe pump or the syringe.

28. The method according to claim 26, further comprising estimating a volume discharged starting from the position of the plunger when the second predetermined threshold was exceeded.

29. The method according to claim 28, further comprising stopping the syringe pump when the estimated volume discharged is equal to or exceeds a target delivery volume.

30. The method according to claim 26, further comprising using an alarm if the plunger traveled into the barrel by the second predetermined distance without the force sensor measuring a force that exceeds the second predetermined threshold.

31. The method according to claim 26, further comprising communicating an actual speed of the plunger to a monitoring client.