Methods, devices, kits and compositions for detecting roundworm, whipworm, and hookworm
First Claim
1. A kit for detection of one or more roundworm coproantigens, one or more whipworm coproantigens and/or one or more hookworm coproantigens in a mammalian sample, the kit comprising:
- (a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm or hookworm coproantigen;
(b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm or hookworm coproantigen; and
(c) a third antibody capable of specifically binding a hookworm coproantigen, but not a whipworm or roundworm coproantigen, and(d) one or more reagents suitable for the detection of the one or more coproantigens.
3 Assignments
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Accused Products
Abstract
Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able to distinguish between one or more helminth infections. Confirmation of the presence or absence of roundworm, whipworm and/or hookworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
49 Citations
32 Claims
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1. A kit for detection of one or more roundworm coproantigens, one or more whipworm coproantigens and/or one or more hookworm coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm or hookworm coproantigen; (b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm or hookworm coproantigen; and (c) a third antibody capable of specifically binding a hookworm coproantigen, but not a whipworm or roundworm coproantigen, and (d) one or more reagents suitable for the detection of the one or more coproantigens. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a whipworm coproantigen; (b) a second antibody capable of specifically binding a whipworm coproantigen, but not a roundworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens. - View Dependent Claims (19, 20, 21, 22, 24, 25, 26, 28, 29, 30, 31, 32)
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17. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a roundworm coproantigen, but not a hookworm coproantigen; (b) a second antibody capable of specifically binding a hookworm coproantigen, but not a roundworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens. - View Dependent Claims (23, 27)
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18. A kit for detection of the presence or absence of one or more helminthic coproantigens in a mammalian sample, the kit comprising:
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(a) a first antibody capable of specifically binding a whipworm coproantigen, but not a hookworm coproantigen; (b) a second antibody capable of specifically binding a hookworm coproantigen, but not a whipworm coproantigen; and (c) one or more reagents suitable for the detection of the one or more helminthic coproantigens.
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Specification