Systems and methods for blood pressure measurement

• US 9,750,419 B2
• Filed: 02/18/2014
• Issued: 09/05/2017
• Est. Priority Date: 02/18/2014
• Status: Active Grant

• Current Assignee: Welch Allyn Incorporated
• Original Assignee: Welch Allyn Incorporated
• Inventors: Whitaker, Tyson B., Quinn, David E., St. Pierre, Shawn C., Kinsley, Matthew J., Lane, John A., Buchanon, Joseph
• Primary Examiner(s): Kahelin, Michael
• Assistant Examiner(s): Alter, Mitchell E
• Application Number:
  US14/183,074
• Publication Number:
  US 20150230718A1
• Time in Patent Office: 1,295 Days
• Field of Search: 600480, 600300, 600485-500
• CPC Class Codes: A61B 5/02116 of pulse wave amplitude A61B5/02225 takes precedence
• CPC Class Codes: A61B 5/02141 Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits A61B5/02233, A61B5/0235 take precedence
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers

Abstract

A method of determining a blood pressure of a patient includes determining a plurality of pressure pulses, wherein each pressure pulse of the plurality of pressure pulses comprises a profile having a maximum profile height. The method also includes determining a pulse score associated with the plurality of pressure pulses, wherein the pulse score is determined based on the profiles of the pressure pulses and the maximum profile heights. The method further includes determining that the pulse score is above a pulse score threshold, and generating, in response to determining that the pulse score is above the pulse score threshold, a pulse curve based on the maximum profile heights. The method also includes determining the blood pressure of the patient without completely occluding a blood vessel of the patient, wherein the blood pressure is determined based on a plurality of values corresponding to respective points on the pulse curve.

Claims

1. A method of determining a blood pressure of a patient, comprising:

disposing a cuff around a limb of the patient;

determining a plurality of pressure pulses during inflation of the cuff, wherein each pressure pulse of the plurality of pressure pulses

comprises a profile having a maximum profile height, and

corresponds to a different respective inflation pressure of the cuff;

determining a pulse score associated with the plurality of pressure pulses, wherein the pulse score is determined by one or more algorithms based on the profiles of the pressure pulses and the maximum profile heights;

determining that the pulse score is above a pulse score threshold;

generating, in response to determining that the pulse score is above the pulse score threshold, a pulse curve based on the maximum profile heights; and

determining the blood pressure of the patient without completely occluding a blood vessel of the patient, wherein the blood pressure is determined by the one or more algorithms based on a plurality of values corresponding to respective points on the pulse curve.

2. The method of claim 1, further comprising

inflating the cuff toward a first target inflation pressure,

wherein the plurality of pressure pulses comprises a plurality of sequential pressure pulses associated with the blood vessel of the patient.

3. The method of claim 2, wherein each maximum profile height is indicative of a maximum force exerted on the cuff during a corresponding pressure pulse of the plurality of pressure pulses, and wherein the maximum force is a result of blood flow through the limb.

4. The method of claim 2, wherein each profile is defined by values indicative of force exerted on the cuff during a corresponding pressure pulse of the plurality of pressure pulses, and wherein the force is a result of blood flow through the limb.

5. The method of claim 2, further comprising:

comparing each maximum profile height to a pressure threshold;

identifying a subset of the maximum profile heights having a value greater than the pressure threshold;

matching the subset of the maximum profile heights with a stored set of profile heights; and

continuing inflation of the cuff toward a second target inflation pressure corresponding to the stored set of profile heights.

6. The method of claim 1, wherein the blood pressure of the patient is determined during inflation of the cuff.

7. The method of claim 1, wherein the plurality of pressure pulses is determined without completely occluding the blood vessel when the cuff is inflated to inflation pressures between a systolic blood pressure of the patient and a diastolic blood pressure of the patient.

8. The method of claim 1, wherein the plurality of pressure pulses comprises a first pulse, a second pulse, and a third pulse,

the first pulse comprising a first profile defined by a first plurality of values, the first plurality of values being indicative of force exerted on a cuff during the first pulse, the first plurality of values including a first maximum profile height,

the second pulse comprising a second profile defined by a second plurality of values, the second plurality of values being indicative of force exerted on the cuff during the second pulse, the second plurality of values including a second maximum profile height,

the third pulse comprising a third profile defined by a third plurality of values, the third plurality of values being indicative of force exerted on the cuff during the third pulse, the third plurality of values including a third maximum profile height, the method further comprising:

generating a first reference curve by averaging values of the first plurality of values with corresponding values of the second plurality of values, the first reference curve being defined by a fourth plurality of values; and

generating a second reference curve by subtracting values of the third plurality of values from corresponding values of the fourth plurality of values.

9. The method of claim 8, wherein the second reference curve is defined by a fifth plurality of values, and wherein the pulse score is determined by using the fifth plurality of values and the maximum profile heights as inputs to the one or more algorithms.

10. The method of claim 1, wherein the plurality of values includes a peak pressure value, the method further comprising:

identifying a first subset of the plurality of values relative to the peak pressure value;

identifying a second subset of the plurality of values relative to the peak pressure value, the second subset of values being exclusive of the first subset of values; and

determining the blood pressure by using the first and second subsets of values, and the peak pressure value, as inputs to the one or more algorithms.

11. The method of claim 10, wherein the plurality of values includes a remainder of values exclusive of the first subset, the second subset, and the peak pressure value, and wherein the blood pressure is determined by the one or more algorithms without the remainder of values.

12. The method of claim 1, wherein the pulse curve comprises a best-fit curve derived from the maximum profile heights, and wherein the plurality of values corresponds to points on the best-fit curve, the method further comprising:

comparing the plurality of values to a stored set of values corresponding to respective points on a predetermined pulse curve; and

determining the blood pressure in response to the comparison.

13. The method of claim 1, further comprising comparing the blood pressure to a blood pressure threshold, and outputting the blood pressure in response to the comparison.

14. The method of claim 1, wherein the blood pressure comprises a systolic pressure and a diastolic pressure, the method further comprising:

comparing the systolic pressure to a first threshold;

comparing the diastolic pressure to a second threshold different from the first threshold; and

determining the blood pressure

in response to comparing at least one of the systolic pressure and the diastolic pressure, and

while an inflation pressure of the cuff if between the systolic pressure and the diastolic pressure.

15. The method of claim 1, wherein the blood pressure comprises a first blood pressure, the pulse curve comprises a first pulse curve, the plurality of values comprises a first plurality of values, and the maximum heights comprise a first plurality of maximum heights, the method further comprising:

generating a second pulse curve based on a second plurality of maximum heights different from the first plurality of maximum heights;

comparing the first plurality of values to values corresponding to points on the second pulse curve; and

outputting the first blood pressure in response to the comparing.

16. A blood pressure measurement system, comprising:

a cuff;

a sensor configured to determine a plurality of pressure pulses of a patient during inflation of the cuff and while the cuff is disposed around a limb of the patient, wherein each pressure pulse of the plurality of pressure pulses

comprises a profile having a maximum profile height, and

corresponds to a different respective inflation pressure of the cuff;

a controller in communication with the sensor, the controller configured to;

determine a pulse score associated with the plurality of pressure pulses, wherein the pulse score is determined by one or more algorithms associated with the controller based on the profiles of the pressure pulses and the maximum profile heights,

determine if the pulse score is above a pulse score threshold,

generate, in response to determining that the pulse score is above the pulse score threshold, a pulse curve based on the maximum profile heights, and

determine the blood pressure of the patient without completely occluding a blood pressure of the patient, wherein the blood pressure is determined based on a plurality of values corresponding to respective points on the pulse curve; and

a user interface in communication with the controller, the user interface configured to output the blood pressure.

17. The system of claim 16, wherein the cuff is selectively inflatable around the limb of the patient under control of the controller.

18. The system of claim 17, wherein the plurality of pressure pulses comprises at least four pressure pulses.

19. The system of claim 17, wherein:

the sensor comprises a pressure transducer;

each maximum profile height is indicative of a maximum force, sensed by the pressure transducer, exerted on the cuff during a corresponding pressure pulse of the plurality of pressure pulses; and

the maximum force is a result of blood flow through the limb.

20. The system of claim 16, further comprising a memory in communication with the controller, the memory including a stored pressure threshold and stored sets of profile heights, wherein the controller is configured to:

compare each maximum profile height to the pressure threshold;

identify a subset of the maximum profile heights having a value greater than the pressure threshold; and

match the subset of the maximum profile heights with at least one set of the stored sets of profile heights.

21. The system of claim 16, further comprising a memory in communication with the controller, the memory including a stored set of values corresponding to points on a predetermined pulse curve, wherein the controller is configured to:

compare the plurality of values to the stored set of values; and

determine the blood pressure in response to the comparison.

22. A method of manufacturing a blood pressure measurement system, comprising:

providing a cuff;

providing a sensor configured to determine a plurality of pressure pulses of a patient during inflation of the cuff and while the cuff is disposed around a limb of the patient, wherein each pressure pulse of the plurality of pressure pulses

comprises a profile having a maximum profile height, and

corresponds to a different respective inflation pressure of the cuff; and

operably connecting the sensor to a controller, the controller configured to;

determine a pulse score associated with the plurality of pressure pulses, wherein the pulse score is determined based on the profiles of the pressure pulses and the maximum profile heights,

determine that the pulse score is above a pulse score threshold,

generate, in response to determining that the pulse score is above the pulse score threshold, a pulse curve based on the maximum profile heights,

determine the blood pressure of the patient without completely occluding a blood vessel of the patient, wherein the blood pressure is determined based on a plurality of values corresponding to respective points on the pulse curve, and

communicate with a user interface, the user interface configured to output the blood pressure.

23. The method of claim 22, further comprising operably connecting the cuff to the controller, the controller being configured to selectively inflate the cuff to the different respective inflation pressures, and wherein the different respective inflation pressures comprise a series of sequentially increasing pressures between a systolic pressure of the patient and a diastolic pressure of the patient.

24. The method of claim 22, further comprising communication between a memory and the controller, the memory including a stored pressure threshold and stored sets of profile heights, wherein the controller is configured to:

compare each maximum profile height to the pressure threshold;

identify a subset of the maximum profile heights having a value greater than the pressure threshold; and

match the subset of the maximum profile heights with at least one set of the stored sets of profile heights.

25. The method of claim 24, wherein the memory further includes a stored set of values corresponding to points on a predetermined pulse curve, wherein the controller is configured to:

compare the plurality of values to the stored set of values; and

determine the blood pressure in response to the comparison.