Porous polymeric formulation prepared using porogens
First Claim
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1. An analyte sensor comprising:
- a crosslinked copolymer network in contact with a surface of an electrode, wherein the crosslinked copolymer network consists of;
backbone chains comprising first methacrylate-derived units and second methacrylate-derived units, wherein each first methacrylate-derived unit has a side chain; and
crosslinks between the second methacrylate-derived units in different backbone chains, wherein the crosslinks comprise poly(alkylene oxide);
an analyte sensing component embedded within the crosslinked copolymer network; and
voids within and defined by the crosslinked copolymer network, wherein the voids are large enough to allow an analyte to pass through the crosslinked copolymer network and small enough to not allow the analyte sensing component to pass through the crosslinked copolymer network.
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Abstract
An analyte sensor for the continuous or semi-continuous monitoring of physiological parameters and a method for making the analyte sensor are disclosed. The analyte sensor includes a crosslinked copolymer network in contact with a surface of an electrode. The copolymer network has voids formed by the removal of a porogen, and an analyte sensing component is immobilized within the network. The method involves forming a solution of the precursors of the copolymer, depositing the mixture on a surface of an electrode, and curing the deposited mixture to provide the analyte sensor.
33 Citations
11 Claims
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1. An analyte sensor comprising:
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a crosslinked copolymer network in contact with a surface of an electrode, wherein the crosslinked copolymer network consists of; backbone chains comprising first methacrylate-derived units and second methacrylate-derived units, wherein each first methacrylate-derived unit has a side chain; and crosslinks between the second methacrylate-derived units in different backbone chains, wherein the crosslinks comprise poly(alkylene oxide); an analyte sensing component embedded within the crosslinked copolymer network; and voids within and defined by the crosslinked copolymer network, wherein the voids are large enough to allow an analyte to pass through the crosslinked copolymer network and small enough to not allow the analyte sensing component to pass through the crosslinked copolymer network. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification