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Haemostatic patch and method of preparation

  • US 9,750,837 B2
  • Filed: 09/25/2013
  • Issued: 09/05/2017
  • Est. Priority Date: 09/25/2012
  • Status: Active Grant
First Claim
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1. A method of preparing a haemostatic patch comprising a porous layer including oxidized cellulose and a film including neutralized chitosan, the film comprising a first free face and a second face fixed on a first face of the porous layer, comprising the following steps:

  • a) preparing a porous layer including oxidized cellulose,b) preparing a film including chitosan starting from an acidic aqueous solution of chitosan,c) fixing the film obtained in b) on a face of the porous layer,d) neutralizing the film obtained in b), wherein step c) is carried out before or after step d) and the neutralizing step d) comprises treating the film with a neutralizing composition comprising at least ethanol and ammonium hydroxide.

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