Drug delivery device with dose capturing module

• US 9,750,886 B2
• Filed: 02/19/2014
• Issued: 09/05/2017
• Est. Priority Date: 02/19/2013
• Status: Active Grant

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Plambech, Christian, Madsen, John Oestergaard, Windum, Jesper Peter
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Hall, Deanna K
• Application Number:
  US14/767,315
• Publication Number:
  US 20150367077A1
• Time in Patent Office: 1,294 Days
• Field of Search: 604211
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/31528 by means of rotational movements, e.g. screw-thread mechanisms
• CPC Class Codes: A61M 5/31533 Dosing mechanisms, i.e. setting a dose administrating mechanisms A61M5/31565
• CPC Class Codes: A61M 5/5086 for indicating if defective, used, tampered with or unsterile

Abstract

A drug delivery system is provided including a drug expelling structure adapted to expel a set dose from a drug-filled cartridge, the expelling structure including a rotational member adapted to rotate relative to a housing and corresponding to a set and/or expelled dose, the system including a sensor adapted to detect a set and/or an expelled dose. The sensor includes a first portion mounted to and rotating with the rotational member, and a second portion including a second rotary sensor part mounted non-rotationally relative to the housing. The first portion includes electronic circuitry, and a first rotary sensor part, and the second portion includes a second rotary sensor part mounted non-rotationally relative to the housing. The first and second rotary sensor parts rotate relative to each other during setting and/or expelling of a dose of drug.

Claims

1. A drug delivery device comprising:

a housing,

a drug-filled cartridge or structure for receiving a drug-filled cartridge, the cartridge comprising an axially displaceable piston and a distal outlet portion,

drug expelling structure comprising;

dose setting structure allowing a user to set a dose of drug to be expelled,

an axially displaceable piston rod adapted to move the piston of a cartridge in a distal direction to thereby expel drug from the cartridge, and

a rotational member adapted to rotate relative to the housing and corresponding to a set and/or expelled dose,

sensor structure adapted to detect a set and/or an expelled dose, comprising;

a first portion mounted to and rotating with the rotational member, comprising;

electronic processor circuitry, and

a first rotary sensor part,

a second portion comprising

a second rotary sensor part mounted non-rotationally relative to the housing,

whereby the first and second rotary sensor parts rotate relative to each other during setting and/or expelling of a dose of drug.

2. A drug delivery device as in claim 1, wherein:

the rotational member is rotated from an initial position to a set position when a dose is set, and

the rotational member is rotated from the set position to the initial position when the set dose is expelled.

3. A drug delivery device as in claim 1, wherein the rotational member is adapted to move axially between an initial and an actuated position, the first portion being mounted to move axially with the rotational member.

4. A drug delivery device as in claim 3, wherein the second portion is mounted to move axially with the rotational member.

5. A drug delivery device as in claim 3, wherein the sensor structure is adapted to detect when the rotational member is moved axially between the initial and the actuated position.

6. A drug delivery device as in claim 1, wherein the electronic processor circuitry comprises logging structure adapted to create a log for dose amounts of drug expelled from a cartridge by the drug expelling structure, wherein the dose amounts are calculated based on relative rotation between the first and second rotary sensor parts during setting and/or expelling of a dose of drug.

7. A drug delivery device as in claim 1, wherein the first portion comprises a display.

8. A drug delivery device as in claim 7, wherein the display is turned off during rotation of the first portion.

9. A drug delivery device as in claim 1, wherein the electronic processor circuitry comprises transmitter structure adapted to transmit stored data to an external receiver.

10. A drug delivery device as in claim 1, wherein the sensor structure is provided in the form of an electronic assembly comprising the first and the second portion, the first portion being in the form of an electronic module, the second portion being rotationally mounted on the electronic module,

wherein the electronic module and the rotational member comprises corresponding interconnecting structure allowing the electronic module to be mounted rotationally locked to the rotational member, and

wherein the second portion and the housing comprises corresponding interconnecting structure allowing the second rotary sensor part to be mounted rotationally locked relative to the housing.

11. A drug delivery device as in claim 1, wherein:

the first rotary sensor part comprises a pattern of a plurality of individual electrically conducting sensor areas connected to the electronic processor circuitry, and

the second rotary sensor part comprises at least one contact structure adapted to engage and connect different sensor areas as the first and second part of the rotary sensor rotate relative to each, the connections being indicative of a rotational position between the first and second portions.

12. A drug delivery device as in claim 11, wherein:

one of the contact structures comprises an axial switch contact having a connected position in which the switch contact is in contact with a sensor area and a dis-connected position in which the switch contact is not in contact with a sensor area, and

the axial switch contact is adapted to be moved between the connected position and the dis-connected position when the second rotary sensor part is moved axially relative to the housing.

13. A drug delivery device as in claim 12, wherein the second rotary sensor part is in the form of a metallic disc member comprising a plurality of integrally formed flexible arms forming the contact structures, at least one of the flexible arms being axially moveable to form a flexible switch arm comprising the axial switch contact.

14. A drug delivery system comprising:

a drug delivery assembly comprising;

a housing,

a drug-filled cartridge or structure for receiving a drug-filled cartridge, the cartridge comprising an axially displaceable piston and a distal outlet portion,

drug expelling structure comprising;

dose setting structure allowing a user to set a dose of drug to be expelled,

an axially displaceable piston rod adapted to move the piston of a cartridge in a distal direction to thereby expel drug from the cartridge,

a rotational member adapted to rotate corresponding to a set and/or expelled dose, and

an axially moveable release member adapted to release the drug expelling structure to thereby expel the set dose of drug,

first and second modules each comprising;

first coupling structure allowing the module to be mounted non-rotationally to the rotational member,

wherein a mounted module serves to transfer an axially directed force acting to move the release member,

wherein the first module comprises no electronic processor circuitry, and

wherein the second module is a self-contained sensor module, comprising;

a first portion comprising;

the first coupling structure,

electronic processor circuitry, and

a first rotary sensor part,

a second portion comprising;

a second rotary sensor part mounted rotationally relative to the housing, and

second coupling structure allowing the second rotary sensor part to be mounted non-rotationally to the housing,

whereby the first and second rotary sensor parts of a mounted sensor module rotate relative to each other during setting and/or expelling of a dose of drug to thereby detect a set and/or expelled dose.

15. A drug delivery system as in claim 14, further comprising a rotatable dose setting member, the rotational member being adapted to rotate corresponding to a set dose,

wherein a mounted module serves to transfer a rotational movement of the dose setting member to the rotatable member.