Computer-aided identification of a tissue of interest

• US 9,754,366 B2
• Filed: 12/17/2013
• Issued: 09/05/2017
• Est. Priority Date: 12/27/2012
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Wiemker, Rafael, Kabus, Sven, Klinder, Tobias
• Primary Examiner(s): Bitar, Nancy
• Application Number:
  US14/651,276
• Publication Number:
  US 20150317792A1
• Time in Patent Office: 1,358 Days
• Field of Search: None
• CPC Class Codes: G06T 11/00 2D [Two Dimensional] image generation
• CPC Class Codes: G06T 11/60 Editing figures and text; Combining figures or text
• CPC Class Codes: G06T 19/20 Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• CPC Class Codes: G06T 2200/24 involving graphical user interfaces [GUIs]
• CPC Class Codes: G06T 2207/10072 Tomographic images
• CPC Class Codes: G06T 2207/30064 Lung nodule
• CPC Class Codes: G06T 2210/41 Medical
• CPC Class Codes: G06T 2219/028 Multiple view windows (top-side-front-sagittal-orthogonal)
• CPC Class Codes: G06T 2219/2012 Colour editing, changing, or manipulating; Use of colour codes
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

A method includes determining a change in a volume of a tissue of interest located in at least two data sets between the at least two data sets. The at least two image data sets include a first image data set acquired at a first time and a second image data set acquired at a second time, and the first and second times are different. The method includes generating a rendering which includes a region in which the tissue of interest is located and indicia that indicates a magnitude of the change across the region. The region is superimposed over the rendering, which is generated based on at least one of the at least two image data sets, and linked to a corresponding image respectively in the at least two image data sets including voxels representing tissue of interest. The method includes visually presenting the rendering in a graphical user interface.

Claims

1. A method, comprising:

determining a change in a volume of a tissue of interest located in at least two data sets, wherein the change is determined between the at least two data sets,

wherein the at least two image data sets include a first image data set acquired at a first time and a follow up second image data set acquired at a second time, and the first and second times are different, wherein the change corresponds to an increase in a physical size of the tissue of interest due to a growth of the tissue of interest between the first and second times;

generating a rendering which includes a region in which the tissue of interest is located and indicia that indicates a magnitude of the change across the region,

wherein the region is superimposed over only a sub-portion of the rendering, which is generated based on at least one of the at least two image data sets, and linked to a corresponding image respectively in the at least two image data sets including voxels representing tissue of interest; and

visually presenting the rendering in a graphical user interface.

2. The method of claim 1, wherein the linking identifies a subset of the at least two image data sets to be evaluated.

3. The method of claim 1, wherein the at least two image data sets are computed tomography image data sets and the region and indicia is rendered to include a “

hot spot”

superimposed over a three dimensional rendering of the computed tomography image data.

4. The method of claim 1, wherein a location and/or a geometry of the region indicates a volume in which the tissue of interest is located.

5. The method of claim 4, wherein a transparency level of the indicia indicates a confidence level that the identified tissue of interest is in the region.

6. The method of claim 4, wherein a color or gray value of the indicia indicates a magnitude of the change in the volume of the tissue of interest across the region.

7. The method of claim 6, wherein the transparency level of the indicia further indicates a confidence level of the magnitude of the change in the volume across the region.

8. The method of claim 1, wherein a shape of the region indicates an estimated size of the tissue of interest.

9. The method of claim 1, wherein the change in volume is determined prior to identifying images of the image data sets for further evaluation.

10. The method of claim 1, further comprising:

visually presenting a first image from the first image data set and a second image from the second image data set based on the link in response to a signal indicative of a user identified portion of the indicia, wherein the first image and the second image correspond to the identified portion of the indicia.

11. An image data processing system, comprising:

a change in tissue volume determiner that is configured to determine a change a volume of a tissue of interest, located in at least two data sets, wherein the change is determined between the at least two data sets,

wherein the at least two image data sets include a first image data set acquired at a first time and a second image data set acquired at a follow up second time, and the first and second times are different, wherein the change corresponds to an increase in a physical size of the tissue of interest due to a growth of the tissue of interest between the first and second times;

a rendering engine that is configured to render a rendering and combine a volume image generated based on the at least two data sets with a likelihood region that indicates a region in which the tissue of interest is located, wherein the region is superimposed over only a sub-portion of the rendering and indicia indicating a change in the volume of the tissue of interest across the region,

wherein the region is linked to a corresponding image respectively in the at least two image data sets including voxels representing tissue of interest; and

a display which is configured to visually present the rendering in a graphical user interface.

12. The image data processing system of claim 11, wherein the linking is configured to identify a subset of the at least two image data sets to be evaluated to confirm the identified tissue of interest.

13. The image data processing system of claim 11, wherein the at least two image data sets are computed tomography image data sets and the indicia is rendered to include a “

hot spot”

superimposed over a three dimensional rendering of the computed tomography image data.

14. The image data processing system of claim 11, wherein a location and/or a geometry of the region indicates a volume in which the tissue of interest is located.

15. The image data processing system of claim 11, wherein a color or gray scale of the indicia indicates a magnitude of the change in the volume of the tissue of interest across the region.

16. The image data processing system of claim 14, wherein a transparency level of the indicia further indicates at least one of a confidence level that the tissue of interest is in the volume or a confidence level of the magnitude of the volume across the region.

17. The image data processing system of claim 11, wherein a shape of the region indicates an estimated size of the tissue of interest.

18. The image data processing system of claim 11, wherein the graphical user interface includes image manipulation tools including at least one of rotate, pan, zoom, window and level.

19. The image data processing system of claim 11, wherein the display visually presents a first image from the first image data set and a second image from the second image data set based on the link in response to a signal indicative of a user identified portion of the indicia, wherein the first image and the second image correspond to the identified portion of the indicia.

20. A computer readable storage medium encoded with computer readable instructions, which, when executed by a processor of a computing system, causes the processor to:

determine a change in a volume of a tissue of interest located in at least in at least two data sets, where the change is determined between the at least two data sets, wherein the first data set is acquired at a first time and the second data set is acquired at a follow up second time, wherein the change corresponds to an increase in a physical size of the tissue of interest due to a growth of the tissue of interest between the first and second times, and generate and visually present a rendering which includes a region in which a tissue of interest is located, wherein the region is super imposed over only a sub-portion of the rendering, first indicia that indicates a change in a magnitude of the volume across the region and second indicia that indicates a confidence that the tissue of interest is located in the region and that the change in magnitude across the region represents the change in magnitude, wherein the first indicia is a color or gray scale value and the second indicia is a transparency level.