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Liquid pharmaceutical composition for the delivery of active ingredients

  • US 9,757,459 B2
  • Filed: 10/18/2011
  • Issued: 09/12/2017
  • Est. Priority Date: 10/20/2010
  • Status: Active Grant
First Claim
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1. A pharmaceutical composition in the form of a suspension comprising a dispersed phase in a liquid continuous phase wherein:

  • (a) The dispersed phase comprises solid particles of an active ingredient, wherein said active ingredient is selected from the group consisting of antibiotic agents, antifungal agents, corticoid, non-steroidal anti-inflammatory agents, and antiviral agents, said ingredient being present in a therapeutically effective amount, and(b) the liquid continuous phase comprises a liquid vehicle comprising a semifluorinated alkane selected from F4H5, F4H6, F6H6 and F6H8;

    wherein the composition is substantially free of water, and wherein the particles of the active ingredient have a volume mean diameter as, measured by laser diffraction of not more than about 15 μ

    m.

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