Devices and methods for sleep apnea treatment

• US 9,757,564 B2
• Filed: 11/10/2015
• Issued: 09/12/2017
• Est. Priority Date: 05/12/2011
• Status: Active Grant

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Bolea, Stephen, Tesfayesus, Wondimeneh, Beck, John, Hoegh, Thomas, Atkinson, Robert, Hauschild, Sidney
• Primary Examiner(s): Layno, Carl H
• Assistant Examiner(s): Piateski, Erin M
• Application Number:
  US14/937,482
• Publication Number:
  US 20160059011A1
• Time in Patent Office: 672 Days
• Field of Search: 607 42
• CPC Class Codes: A61B 2017/248 Operations for treatment of snoring, e.g. uvulopalatoplasty
• CPC Class Codes: A61F 5/566 Intra-oral devices
• CPC Class Codes: A61N 1/3601 of respiratory organs
• CPC Class Codes: A61N 1/3611 Respiration control stimulating respiratory organs A61N1/3601

Abstract

Devices and methods for improving the coupling between the soft palate and the genioglossus. This may be accomplished, for example, but shortening or stiffening the palatoglossal arch. Improved coupling between the soft palate and the genioglossus may be beneficial to a patient suffering from obstructive sleep apnea (OSA) as a stand-alone procedure, or in combination procedures and devices that cause anterior displacement of the tongue such as hypoglossal nerve stimulation, genioglossus advancement surgery, mandibular advancement surgery, mandibular advancement (oral) appliances, etc.

Claims

1. A method of treating an upper airway tissue collapse condition of a patient, comprising:

implanting at least one tissue engagement member in the patient'"'"'s upper airway tissue to improve a coupling between the patient'"'"'s genioglossus muscle and a portion of the patient'"'"'s upper airway tissue, wherein the at least one tissue engagement member extends between the patient'"'"'s genioglossus muscle and a portion of the patient'"'"'s upper airway tissue, the implanting of the at least one tissue engagement member having an efficacy in the treatment of the upper airway tissue collapse condition; and

providing a stimulation therapy that delivers an electrical stimulation to a hypoglossal nerve of the patient to cause an advancement of the patient'"'"'s genioglossus muscle and/or an anterior movement of the patient'"'"'s tongue,

wherein the stimulation therapy improves the efficacy in the treatment of the upper airway tissue collapse condition associated with the at least one tissue engagement member.

2. A method as in claim 1, wherein improving the coupling between the patient'"'"'s genioglossus muscle and the portion of the patient'"'"'s upper airway tissue includes tightening the patient'"'"'s pharyngeal tissue.

3. A method as in claim 2, wherein tightening the patient'"'"'s pharyngeal tissue includes shortening the patient'"'"'s palatoglossus.

4. A method as in claim 2, wherein tightening the patient'"'"'s pharyngeal tissue includes shortening the patient'"'"'s palatopharyngeus.

5. A method as in claim 2, wherein tightening the patient'"'"'s pharyngeal tissue includes shortening the patient'"'"'s pharyngoepiglottic fold.

6. A method as in claim 1, wherein the stimulation therapy causes genioglossus contraction.

7. The method as in claim 1, wherein the upper airway tissue collapse condition is an obstructive sleep apnea condition of the patient, and wherein the stimulation therapy mitigates the obstructive sleep apnea condition.

8. The method as in claim 1, wherein the upper airway tissue collapse condition includes a first tissue collapse at a first location within the patient'"'"'s upper airway and a second tissue collapse at a second location within the patient'"'"'s upper airway, wherein the stimulation therapy corresponds to a mitigation of the first tissue collapse at the first location, and wherein the efficacy associated with the at least one tissue engagement member corresponds to a mitigation of the second tissue collapse at the second location.

9. The method as in claim 1, wherein the upper airway tissue collapse condition includes a first tissue collapse at a first location within the patient'"'"'s upper airway and a second tissue collapse at a second location within the patient'"'"'s upper airway, wherein the stimulation therapy corresponds to a mitigation of the first tissue collapse, and wherein a movement of the upper airway due to the stimulation therapy and the at least one tissue engagement member corresponds to a mitigation of both the first tissue collapse and the second tissue collapse.