Method and device for displaying predicted volume of influence
First Claim
1. A computer-implemented method of outputting information concerning an electrode inserted inside a patient'"'"'s neural tissue, the method comprising:
- determining, by a computer processor, a distribution of electrical values, to be generated by the inserted electrode using a first set of settings, over a plurality of positions in the patient'"'"'s neural tissue in a region surrounding the inserted electrode;
determining at least one threshold electrical value for neural tissue activation;
determining, by the processor and by applying the at least one threshold electrical value to the electrical values to be generated by the inserted electrode using the first set of settings, an estimated volume of neural tissue activated by the inserted electrode using the first set of settings, wherein the estimated volume of neural tissue indicates that the distribution of the electrical values inside the estimated volume of neural tissue exceed the at least one threshold electrical value and indicates that the distribution of the electrical values beyond the estimated volume of neural tissue fail to exceed the at least one threshold electrical value; and
outputting, by the processor, a graphical representation of the determined estimated volume.
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Abstract
This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.
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Citations
20 Claims
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1. A computer-implemented method of outputting information concerning an electrode inserted inside a patient'"'"'s neural tissue, the method comprising:
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determining, by a computer processor, a distribution of electrical values, to be generated by the inserted electrode using a first set of settings, over a plurality of positions in the patient'"'"'s neural tissue in a region surrounding the inserted electrode; determining at least one threshold electrical value for neural tissue activation; determining, by the processor and by applying the at least one threshold electrical value to the electrical values to be generated by the inserted electrode using the first set of settings, an estimated volume of neural tissue activated by the inserted electrode using the first set of settings, wherein the estimated volume of neural tissue indicates that the distribution of the electrical values inside the estimated volume of neural tissue exceed the at least one threshold electrical value and indicates that the distribution of the electrical values beyond the estimated volume of neural tissue fail to exceed the at least one threshold electrical value; and outputting, by the processor, a graphical representation of the determined estimated volume. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A computer-implemented method of outputting information concerning an electrode inserted inside a patient'"'"'s neural tissue, the method comprising:
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determining, by a computer processor, a distribution of electrical values, to be generated by the inserted electrode, in the patient'"'"'s neural tissue in a region surrounding the inserted electrode; determining at least one threshold electrical value for neural tissue activation; determining, by the processor and by applying the at least one threshold electrical value to the electrical values, an estimated volume of neural tissue activated by the distribution of the electrical values; and outputting, by the processor, a graphical representation of the determined estimated volume, wherein determining the distribution of the electrical values, to be generated by the inserted electrode in the patient'"'"'s neural tissue in the region surrounding the inserted electrode further comprises; determining one or more models of the patient'"'"'s neural tissue in the region surrounding the inserted electrode, wherein the one or more models have a plurality of data densities that vary as a function of distance from the inserted electrode; and determining the distribution throughout the patient'"'"'s neural tissue in the region surrounding the inserted electrode of the electrical values to be generated by the inserted electrode based on the one or more models. - View Dependent Claims (17)
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18. A non-transitory computer-readable medium having computer executable instructions stored thereon that, when executed by a processor, cause the processor to perform a method for outputting information concerning an electrode inserted inside a patient'"'"'s neural tissue, the method comprising:
- determining a distribution of electrical values, to be generated by the inserted electrode using a first set of settings, over a plurality of positions in the patient'"'"'s neural tissue in a region surrounding the inserted electrode;
determining at least one threshold electrical value for neural tissue activation;
determining, by applying the at least one threshold electrical value to the electrical values to be generated by the inserted electrode using the first set of settings, an estimated volume of neural tissue activated by the inserted electrode using the first set of settings, wherein the estimated volume of neural tissue indicates that the distribution of the electrical values inside the estimated volume of neural tissue exceed the at least one threshold electrical value and indicates that the distribution of the electrical values beyond the estimated volume of neural tissue fail to exceed the at least one threshold electrical value; and
outputting a graphical representation of the determined estimated volume. - View Dependent Claims (19, 20)
- determining a distribution of electrical values, to be generated by the inserted electrode using a first set of settings, over a plurality of positions in the patient'"'"'s neural tissue in a region surrounding the inserted electrode;
Specification