Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
First Claim
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1. An electrochemical continuous glucose sensor configured for implantation in a host, the glucose sensor comprising:
- an electrode configured to measure a signal indicative of a glucose concentration of a host, wherein the signal comprises a glucose-related component and a non-glucose related component; and
an enzyme-containing membrane covering at least a portion of the electrode, wherein the enzyme-containing membrane comprises an outer domain comprising a discontinuously hydrophilic surface, wherein the outer domain is formed from a blend, wherein the outer domain comprises at least about 5 wt. % of a hydrophilic component;
wherein the glucose sensor has a sensitivity to glucose of from about 25 pA/mg/dL to about 500 pA/mg/dL.
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Abstract
Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.
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8 Claims
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1. An electrochemical continuous glucose sensor configured for implantation in a host, the glucose sensor comprising:
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an electrode configured to measure a signal indicative of a glucose concentration of a host, wherein the signal comprises a glucose-related component and a non-glucose related component; and an enzyme-containing membrane covering at least a portion of the electrode, wherein the enzyme-containing membrane comprises an outer domain comprising a discontinuously hydrophilic surface, wherein the outer domain is formed from a blend, wherein the outer domain comprises at least about 5 wt. % of a hydrophilic component; wherein the glucose sensor has a sensitivity to glucose of from about 25 pA/mg/dL to about 500 pA/mg/dL. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification