Electronic stimulation system and device thereof for dorsal root ganglion

• US 9,764,137 B2
• Filed: 10/01/2015
• Issued: 09/19/2017
• Est. Priority Date: 10/01/2014
• Status: Active Grant

• Current Assignee: GiMer Medical Co., Ltd.
• Original Assignee: GiMer Medical Co., Ltd.
• Inventors: Lin, Chii-Wann, Chang, Chi-Heng, Wen, Yeong-Ray, Lin, Wei-Tso
• Primary Examiner(s): CAREY, MICHAEL JAMES
• Application Number:
  US14/872,767
• Publication Number:
  US 20160096021A1
• Time in Patent Office: 719 Days
• Field of Search: 607 68, 607 72, 607 76, 607117
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/06 for high-frequency therapy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36171 Frequency

Abstract

An electronic stimulation device for electrically stimulating at least one dorsal root ganglion with relative low pain sensations without generating relative much sensations of paresthesia comprises at least one electronic stimulation unit. The electronic stimulation unit includes at least one first electrode and at least one second electrode, and it delivers a high-frequency electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field. The frequency of the high-frequency electrical stimulation signal ranges from 200 kHz to 1000 kHz.

Claims

1. An electronic stimulation device for electrically stimulating at least one dorsal root ganglion, comprising:

at least one electronic stimulation unit including at least one first electrode and at least one second electrode, wherein the electronic stimulation unit delivers an electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field without destroying neural cells of the dorsal root ganglion, and the frequency of the electrical stimulation signal ranges from 200 kHz to 1000 kHz,

wherein the electronic stimulation device is configured for implantation inside a human body,

wherein the electrical stimulation signal blocks neurotransmission to the dorsal root ganglion through a C-fiber, and

wherein the electronic stimulation unit delivers the electrical stimulation signal for a second time from 2 hours to 7 days after the electronic stimulation unit delivers the electrical signal for a first time, so as to electrically stimulate the human body again.

2. The electronic stimulation device according to claim 1, wherein the electrical stimulation signal is a pulse signal and its pulse frequency ranges from 0 to 1 kHz.

3. The electronic stimulation device according to claim 1, wherein the voltage of the electrical stimulation signal ranges from −

10V to −

1V or ranges from 1V to 10v, and its current ranges from 2 mA to 50 mA.

4. The electronic stimulation device according to claim 1, wherein the individual length of the first electrode and the second electrode ranges from 1 mm to 3 mm.

5. The electronic stimulation device according to claim 1, wherein a first interval distance exists between the first electrode and the second electrode, and the first interval distance ranges from 3 mm to 7 mm.

6. The electronic stimulation device according to claim 1, wherein a second interval distance exists between the first electrode, the second electrode and the dorsal root ganglion, and the second interval distance ranges from 0 to 10 mm.

7. The electronic stimulation device according to claim 1, wherein the electronic stimulation unit is a straight line, a ring, an arc, a spiral or a helix, the electronic stimulation unit includes at least two first electrodes and at least two second electrodes, and when the electronic stimulation unit is the ring, the arc, the spiral or the helix, the first electrodes and the second electrodes surround the dorsal root ganglion.

8. The electronic stimulation device according to claim 1, wherein the electronic stimulation unit includes a plurality of the first electrodes and a plurality of the second electrodes, and the first electrodes and the second electrodes are arranged in an array.

9. An electronic stimulation system for electrically stimulating at least one dorsal root ganglion, comprising:

a control unit; and

an electronic stimulation device comprising an electronic stimulation unit including at least one first electrode and at least one second electrode, wherein the electronic stimulation unit delivers an electrical stimulation signal to impel the first electrode and the second electrode to generate an electric field without destroying neural cells of the dorsal root ganglion, and the frequency of the electrical stimulation signal ranges from 200 kHz to 1000 kHz,

wherein the electronic stimulation device is configured for implantation inside a human body,

wherein the electrical stimulation signal blocks neurotransmission to the dorsal root ganglion through a C-fiber, and

wherein the electronic stimulation unit delivers the electrical stimulation signal for a second time from 2 hours to 7 days after the electronic stimulation unit delivers the electrical signal for a first time, so as to electrically stimulate the human body again.

10. An electronic stimulation method for blocking neurotransmission to the dorsal root ganglion through a C-fiber using an electromagnetic stimulation device, wherein the electromagnetic stimulation device has at least a first electrode and at least a second electrode, and the first and second electrodes are separated by a first distance, the electronic stimulation method comprising:

implanting the electromagnetic stimulation device inside a human body so as to position the electromagnetic stimulation device at least at a second distance away from one dorsal root ganglion, wherein the second distance is a minimum linear distance between the electromagnetic stimulation device and the dorsal root ganglion, and the second distance ranges no more than 10 mm; and

delivering an electrical stimulation signal so as to apply a preset voltage to the first and second electrodes and so that an electromagnetic field covering and stimulating the dorsal root ganglion without destroying neural cells of the dorsal root ganglion is produced between the first and second electrodes,

wherein the preset voltage is no more than 10V and has a frequency between 200 KHz to 1000 kHz, and an electric field strength of the electromagnetic field covering the dorsal root ganglion ranges from 100 V/m to 1000 V/m,

wherein the electrical stimulation signal blocks neurotransmission to the dorsal root ganglion through a C-fiber,

wherein the electronic stimulation method further comprising the step of;

delivering the electrical stimulation signal for a second time from 2 hours to 7 days after delivering the electrical signal for a first time, so as to electrically stimulate the human body again.

11. The electronic stimulation method according to claim 10, wherein the preset voltage ranges from +1V to +10V, or ranges from −

1V to −

10V, and the preset voltage has a current ranging from 2 mA to 50 mA.

12. The electronic stimulation method according to claim 10, wherein each of the first and second electrodes have a length ranging from 1 mm to 3 mm.

13. The electronic stimulation method according to claim 10, wherein the first and second electrodes are configured on an insulating member, and the first distance ranges from 3 mm to 7 mm.

14. The electronic stimulation method according to claim 10, wherein the electromagnetic stimulation device is a straight line shape, a ring shape, an arc shape, a spiral shape or a helix shape.

15. The electronic stimulation method according to claim 10, wherein the electromagnetic stimulation device includes a plurality of the first electrodes and a plurality of the second electrodes, and the first electrodes and the second electrodes are arranged in an array.