Detection of nucleic acids from multiple types of human papillomavirus
First Claim
Patent Images
1. A mixture of oligomers in which individual oligomer sequences are selected from the group consisting of SEQ ID NO:
- 11 to SEQ ID NO;
17, SEQ ID NO;
44 to SEQ ID NO;
54 and SEQ ID NO;
58, which includes the complementary oligomer sequences or RNA equivalents of the specified sequences, wherein the mixture includes;
SEQ ID Nos. 11 to 17, or complementary oligomer sequences or RNA equivalents of the oligomer sequences;
SEQ ID Nos. 11 to 15 and 17, or complementary oligomer sequences or RNA equivalents of the oligomer sequences;
SEQ ID Nos. 11 to 15 and 17 and at least one oligomer of SEQ ID NO;
44 to SEQ ID NO;
54 and SEQ ID NO;
58, or complementary oligomer sequences or RNA equivalents of the oligomer sequences;
orSEQ ID Nos. 11, 12, 14, 15, 17, 44, 45 and 52, or complementary oligomer sequences or RNA equivalents of the oligomer sequenceswherein at least one of the oligomer sequences in the mixture of oligomers includes a label joined directly or indirectly to the oligomer sequence.
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Abstract
Nucleic acid oligonucleotide sequences are disclosed which include amplification oligomers and probe oligomers which are useful for detecting multiple types of human papillomaviruses (HPV) associated with cervical cancer. Methods for detecting multiple HPV types in biological specimens by amplifying HPV nucleic acid sequences in vitro and detecting the amplified products are disclosed.
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Citations
19 Claims
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1. A mixture of oligomers in which individual oligomer sequences are selected from the group consisting of SEQ ID NO:
- 11 to SEQ ID NO;
17, SEQ ID NO;
44 to SEQ ID NO;
54 and SEQ ID NO;
58, which includes the complementary oligomer sequences or RNA equivalents of the specified sequences, wherein the mixture includes;SEQ ID Nos. 11 to 17, or complementary oligomer sequences or RNA equivalents of the oligomer sequences; SEQ ID Nos. 11 to 15 and 17, or complementary oligomer sequences or RNA equivalents of the oligomer sequences; SEQ ID Nos. 11 to 15 and 17 and at least one oligomer of SEQ ID NO;
44 to SEQ ID NO;
54 and SEQ ID NO;
58, or complementary oligomer sequences or RNA equivalents of the oligomer sequences;
orSEQ ID Nos. 11, 12, 14, 15, 17, 44, 45 and 52, or complementary oligomer sequences or RNA equivalents of the oligomer sequences wherein at least one of the oligomer sequences in the mixture of oligomers includes a label joined directly or indirectly to the oligomer sequence. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
- 11 to SEQ ID NO;
Specification