Dynamic radially controlled light input to a noninvasive analyzer apparatus and method of use thereof
First Claim
1. An apparatus for noninvasively determining an analyte concentration at a sample site of a subject, comprising:
- a noninvasive analyzer, comprising;
a source configured to provide photons;
means for independently irradiating as a function of time each member of a set of mean radial distances from a center of the sample site of the subject with the photons, said means for independently irradiating comprising a vibration reduction system for maintaining an offset distance between said means for independently irradiating and a surface of the sample site;
wherein a first member of said set of mean radial distances, comprises a first distance of less than two and a half millimeters and greater than six hundred micrometers,wherein a second member of said set of mean radial distances comprises a second distance of less than one millimeter and greater than one-quarter millimeter, andwherein a third member of said set of mean radial distances comprises a third distance of less than one-half millimeter; and
a detector configured to sequentially detect the photons traversing through each member of said set of mean radial distances independently of remaining members of said set of mean radial distances, said analyzer configured to use the detected photons in determination of the analyte concentration.
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Accused Products
Abstract
An analyzer apparatus and method of use thereof is described to dynamically irradiate a sample with incident light where the incident light is varied in time in terms of any of: position, radial position relative to a point of the skin of a subject, solid angle, incident angle, depth of focus, energy, and/or intensity. For example, the incident light is varied in radial position as a function of time relative to one or more of a sample site, a point on skin of the subject, a detection optic, and/or a sample volume observed by a detection system. The radially varied incident light is used to enhance and/or vary light probing the epidermis, the dermis, and/or the subcutaneous fat of the subject or of a group of subjects.
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Citations
12 Claims
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1. An apparatus for noninvasively determining an analyte concentration at a sample site of a subject, comprising:
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a noninvasive analyzer, comprising; a source configured to provide photons; means for independently irradiating as a function of time each member of a set of mean radial distances from a center of the sample site of the subject with the photons, said means for independently irradiating comprising a vibration reduction system for maintaining an offset distance between said means for independently irradiating and a surface of the sample site; wherein a first member of said set of mean radial distances, comprises a first distance of less than two and a half millimeters and greater than six hundred micrometers, wherein a second member of said set of mean radial distances comprises a second distance of less than one millimeter and greater than one-quarter millimeter, and wherein a third member of said set of mean radial distances comprises a third distance of less than one-half millimeter; and a detector configured to sequentially detect the photons traversing through each member of said set of mean radial distances independently of remaining members of said set of mean radial distances, said analyzer configured to use the detected photons in determination of the analyte concentration. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A method for noninvasively determining an analyte concentration at a sample site of a subject, comprising the steps of:
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using a source of an analyzer to provide photons; guiding the photons with a photon transport system to a set of mean radial distances from a center of the sample site of the subject; maintaining an offset distance between the photon transport system and a surface of the sample site using a vibration reduction system; wherein a first member of said set of mean radial distances, comprises a first distance of less than two and a half millimeters and greater than six hundred micrometers, wherein a second member of said set of mean radial distances comprises a second distance of less than one millimeter and greater than one-half millimeter, and wherein a third member of said set of radial distances comprises a third distance of less than one-half millimeter; and sequentially detecting the photons traversing through each of said first member, said second member, and said third member of said set of mean radial distances independently of detection of the photons of remaining member distances of said first member, said second member, and said third member of said set of mean radial distances. - View Dependent Claims (10, 11, 12)
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Specification