Systems and methods for analyzing a physiological sensor signal

• US 9,770,210 B2
• Filed: 09/23/2011
• Issued: 09/26/2017
• Est. Priority Date: 09/23/2011
• Status: Active Grant

• Current Assignee: Nellcor Puritan Bennett Ireland
• Original Assignee: Nellcor Puritan Bennett Ireland
• Inventors: Addison, Paul S., Watson, James
• Primary Examiner(s): Thomson, William
• Assistant Examiner(s): JIAN, SHIRLEY XUEYING
• Application Number:
  US13/243,619
• Publication Number:
  US 20130079601A1
• Time in Patent Office: 2,195 Days
• Field of Search: None
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

The present disclosure relates generally to patient monitoring systems and, more particularly, to signal analysis for patient monitoring systems. In one embodiment, a method of analyzing a detector signal of a physiological patient sensor includes obtaining the detector signal from the physiological patient sensor, wherein the detector signal crosses a horizontal boundary more than once. The method also includes determining the relative time and the slope of the detector signal at each boundary crossing. The method further includes estimating the amplitude of the detector signal based, at least in part, on the determined relative time and slope of the detector signal at each boundary crossing. The method also includes determining a physiological parameter of a patient based, at least in part, on the estimate of the amplitude of the detector signal.

Claims

1. A method for analyzing a detector signal of a physiological patient sensor, comprising:

receiving the detector signal from the physiological patient sensor at a processor, wherein the detector signal crosses a horizontal boundary more than once;

using the processor, determining a relative time and a slope of the detector signal at each point at which the detector signal crosses the horizontal boundary;

using the processor, estimating an amplitude of the detector signal based, at least in part, on the determined relative time and slope of the detector signal at each point at which the detector signal crosses the horizontal boundary; and

using the processor, determining a physiological parameter of a patient based, at least in part, on the estimate of the amplitude of the detector signal.

2. The method of claim 1, wherein the horizontal boundary is a zero boundary.

3. The method of claim 1, wherein determining the relative time of the detector signal at each point at which the detector signal crosses the horizontal boundary comprises determining the periodicity or the frequency of the points at which the detector signal crosses the horizontal boundary.

4. The method of claim 1, wherein determining the slope of the detector signal at each point at which the detector signal crosses the horizontal boundary comprises determining the derivative of the detector signal at each point at which the detector signal crosses the horizontal boundary.

5. The method of claim 1, wherein estimating the amplitude of the detector signal comprises multiplying values of the determined slopes of the detector signal at two adjacent points at which the detector signal crosses the horizontal boundary by the determined relative time between the two adjacent points.

6. The method of claim 1, wherein estimating the amplitude of the detector signal comprises estimating the amplitude of the detector signal using a probabilistic or stochastic method comprising non-parametric Bayesian estimates, neural networks, or any combination thereof.

7. The method of claim 1, wherein estimating the amplitude of the detector signal comprises estimating the amplitude of the detector signal using an adaptive rule-based system comprising propositional or predicate calculus, Modal, non-monotonic, or fuzzy logic, or any combination thereof.

8. The method of claim 1, wherein determining a physiological parameter of a patient comprises determining a pulse rate, oxygen saturation, respiration rate, respiration effort, continuous non-invasive blood pressure, cardiac output, fluid responsiveness, perfusion, pulse rhythm type, hydration level, or any combination thereof.

9. The method of claim 1, comprising displaying the physiological parameter on a display.

10. A patient monitoring system, comprising:

a patient monitor comprising;

an input configured to receive a detector signal from a physiological sensor; and

a processor configured to;

locate a portion of the detector signal between two adjacent intersections of the detector signal and a horizontal axis;

determine an amount of time between the two intersections of the detector signal and the horizontal axis;

determine a gradient for the detector signal at the two intersections of the detector signal and the horizontal axis; and

estimate the amplitude of the portion of the detector signal between the two intersections based, at least in part, on the determined amount of time between the two intersections and the determined gradients for the detector signal at the two intersections.

11. The system of claim 10, wherein the processor is configured to estimate the amplitude of the portion of the detector signal by multiplying mean, absolute values of the determined gradients of the two intersections by the amount of time between the two intersections.

12. The system of claim 10, wherein estimating the amplitude of the detector signal comprises estimating the amplitude of the detector signal using a probabilistic or stochastic method comprising non-parametric Bayesian estimates, neural networks, or any combination thereof.

13. The system of claim 10, wherein estimating the amplitude of the detector signal comprises estimating the amplitude of the detector signal using an adaptive rule-based system comprising propositional or predicate calculus, Modal, non-monotonic, or fuzzy logic, or any combination thereof.