Apparatus and methods for ocular injection
First Claim
1. An apparatus, comprising:
- a housing configured to receive at least a portion of a medicament container;
an adjustment member operably coupled to the housing and a puncture member;
a hub, the hub coupled to the housing and defining a passageway configured to receive the puncture member therethrough, the hub having a distal end surface, the distal end surface of the hub configured to contact a target surface of a target tissue when a substance is conveyed through the puncture member; and
an actuation rod, the actuation rod configured to be coupled to the medicament container, the actuation rod, the adjustment member, and the puncture member collectively configured such that (1) (a) a distal end portion of the actuation rod moves within the medicament container, (b) a length of the puncture member extending distally from the distal end surface of the hub increases, and (c) the adjustment member transitions from a first configuration to a second configuration, in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a first region of the target tissue, and (2) movement of the puncture member relative to the distal end surface of the hub in response to the force on the actuation rod is limited when the distal end portion of the puncture member is disposed within a second region of the target tissue, the adjustment member being in the second configuration when the distal end portion of the puncture member is disposed within the second region, the force having a magnitude less than a threshold value.
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0 Petitions
Accused Products
Abstract
An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.
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Citations
30 Claims
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1. An apparatus, comprising:
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a housing configured to receive at least a portion of a medicament container; an adjustment member operably coupled to the housing and a puncture member; a hub, the hub coupled to the housing and defining a passageway configured to receive the puncture member therethrough, the hub having a distal end surface, the distal end surface of the hub configured to contact a target surface of a target tissue when a substance is conveyed through the puncture member; and an actuation rod, the actuation rod configured to be coupled to the medicament container, the actuation rod, the adjustment member, and the puncture member collectively configured such that (1) (a) a distal end portion of the actuation rod moves within the medicament container, (b) a length of the puncture member extending distally from the distal end surface of the hub increases, and (c) the adjustment member transitions from a first configuration to a second configuration, in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a first region of the target tissue, and (2) movement of the puncture member relative to the distal end surface of the hub in response to the force on the actuation rod is limited when the distal end portion of the puncture member is disposed within a second region of the target tissue, the adjustment member being in the second configuration when the distal end portion of the puncture member is disposed within the second region, the force having a magnitude less than a threshold value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. An apparatus, comprising:
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a housing configured to receive at least a portion of a medicament container; a hub, the hub coupled to the housing and defining a passageway configured to receive a puncture member therethrough, the hub having a distal end surface, the distal end surface of the hub configured to contact a target surface of a target tissue; an adjustment member operably coupled to the puncture member; and an actuation rod, the actuation rod configured to be coupled to the medicament container, the adjustment member configured to transition from a first configuration to a second configuration in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a first region of the target tissue, a length of the puncture member extending distally from the distal end surface of the hub increasing in response to the adjustment member transitioning from the first configuration to the second configuration, the force having a magnitude less than a threshold value. - View Dependent Claims (21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
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Specification