Anti-bolus control method and corresponding device

• US 9,770,550 B2
• Filed: 09/29/2010
• Issued: 09/26/2017
• Est. Priority Date: 10/02/2009
• Status: Active Grant

• Current Assignee: Fresenius Vial SAS (Else Kröner-Fresenius-Stiftung)
• Original Assignee: Fresenius Vial SAS (Else Kröner-Fresenius-Stiftung)
• Inventors: Traversaz, Philippe, Archat, Damien
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): LEE, WENG WAH
• Application Number:
  US13/499,734
• Publication Number:
  US 20120215170A1
• Time in Patent Office: 2,554 Days
• Field of Search: 128DIG 1, 128DIG 12, 128DIG 13, 604 65- 67, 604131
• CPC Class Codes: A61M 5/14546 Front-loading type injectors
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir

Abstract

For controlling the movement of the push device of a pump of the syringe driver-type, the pump comprising a casing (100), a syringe cradle (200) for a syringe (400), a push device (300) mobile relative to the casing (100) and capable of being driven in rotation parallel to the longitudinal axis of the syringe by driving means, clutch means (310, 350, 351) for engaging or disengaging the push device on the driving means, the push device is disengaged from the driving means, in order to move it manually, and the presence or absence of a contact between the push device and the syringe head is determined. If the push device is not in contact with the syringe head, it is advanced manually. Blocking of the advance movement of the push device is triggered only if, at the beginning, the push device was not in contact with the syringe head.

Claims

1. Method of controlling the movement of a push device of a pump of the syringe driver-type, the pump comprising a casing, a syringe cradle in which a syringe is placed, a push device mobile relative to the casing and capable of being driven in translation parallel to the longitudinal axis of the syringe, and a clutch having an engaged configuration engaging the push device to be driven in translation and a disengaged configuration disengaging the push device from being driven in translation, said method comprising:

a) setting the clutch in the disengaged configuration disengaging the push device;

b) detecting the presence or absence of contact between the push device and a piston head of the syringe;

c) detecting the absence of contact between the push device and the piston head of the syringe, and while the push device is disengaged, moving the push device in translation toward the syringe until there is contact between the push device and the piston head of the syringe, detecting the contact of the push device with the piston head of the syringe, and immediately blocking the translation movement of the push device, wherein said blocking had been inactivated up to then.

2. Method according to claim 1, comprising the following additional steps performed after step c):

d) setting the clutch in the engaged configuration engaging the push device;

e) unblocking the translation movement of the push device.

3. Method according to claim 2, comprising the following additional steps performed after step e):

f) setting the clutch in the disengaged configuration disengaging the push device;

g) moving in translation, by the desired amplitude, the push device in contact with the piston head in the direction of the syringe;

h) stopping the movement of the push device and setting the clutch in the engaged configuration engaging the push device.

4. Method according to claim 1, comprising the following additional steps performed after step b):

b′

) detecting the presence of a contact between the push device and the piston head, and moving in translation, by the desired amplitude, the push device in contact with the piston head in the direction of the syringe;

b″

) stopping the movement of the push device and setting the clutch in the engaged configuration engaging the push device.

5. Method according to claim 2, comprising the following additional step performed after step e):

e′

) driving the push device in translation.

6. Method according to claim 2, said method being applied to a pump whose push device is driven by a threaded driving rod by two half-nuts capable of being moved between an engaged position in which the two half-nuts are brought close to each other and surrounding the threaded driving rod so that they can move on the threaded driving rod only when the threaded driving rod is set in rotation, and a disengaged position in which the two half-nuts are brought away from each other and from the threaded driving rod so that they no longer cooperate with the threaded driving rod, said method comprising the following intermediate steps performed after the engagement of step d):

d′

) detecting the relative position of the half-nuts;

d″

) if the two half-nuts have not reached the engaged position, setting the threaded driving rod in rotation, until the two half-nuts have reached the engaged position.

14. Method according to claim 6, wherein, in step d″

), if the two half-nuts have not reached the engaged position, the threaded driving rod is set in rotation by controlling the effort generated by the push device on the syringe via a force sensor integrated with the push device.

15. Method according to claim 3, comprising the following additional step performed after step h):

i) driving the push device in translation.

16. Method according to claim 4, comprising the following additional step performed after step b″

);

b″

′

) driving the push device in translation.

17. Method according to claim 3, said method being applied to a pump whose push device is driven by a threaded driving rod by two half-nuts capable of being moved between an engaged position in which the two half-nuts are brought close to each other and surrounding the threaded driving rod so that they can move on the threaded driving rod only when the threaded driving rod is set in rotation, and a disengaged position in which the two half-nuts are brought away from each other and from the threaded driving rod so that they no longer cooperate with the threaded driving rod, said method comprising the following intermediate steps performed after the engagement of step h):

h′

) detecting the relative position of the half-nuts;

h″

) if the two half-nuts have not reached the engaged position, setting the threaded driving rod in rotation, until the two half-nuts have reached the engaged position.

18. Method according to claim 4, said method being applied to a pump whose push device is driven by a threaded driving rod by two half-nuts capable of being moved between an engaged position in which the two half-nuts are brought close to each other and surrounding the threaded driving rod so that they can move on the threaded driving rod only when the threaded driving rod is set in rotation, and a disengaged position in which the two half-nuts are brought away from each other and from the threaded driving rod so that they no longer cooperate with the threaded driving rod, said method comprising the following intermediate steps performed after the engagement of step b″

);

b″

′

) detecting the relative position of the half-nuts;

b″

″

) if the two half-nuts have not reached the engaged position, setting the threaded driving rod in rotation, until the two half-nuts have reached the engaged position.

22. Method according to claim 1, wherein the push device is being driven in translation by a motor.

23. Method according to claim 1, wherein the push device is being driven in translation by driving means.

24. Method according to claim 23, wherein the translation movement of the push device is blocked by actuating means for blocking the translation movement of the push device.

7. Pump of the syringe driver-type comprising

a casing,

a syringe cradle intended to receive a syringe,

a push device mobile relative to the casing and capable of being driven in translation parallel to the longitudinal axis of the syringe,

a clutch having an engaged configuration engaging the push device to be driven in translation and a disengaged configuration disengaging the push device from being driven in translation, and

means for blocking the movement of the push device toward the syringe when the push device contacts a piston head of the syringe during a movement from a position without contact with the piston head of the syringe toward a position in contact with the piston head of the syringe,

wherein the means for blocking the push device comprise (i) a threaded control rod, (ii) a threaded nut engaged on the threaded control rod and integral with the push device, and (iii) a brake acting on the threaded control rod.

8. Pump according to claim 7, wherein the brake is constituted by an electromagnetic brake comprising a rotor integral with the threaded control rod and a stator integral with the casing.

9. Pump according to claim 7, wherein the push device is equipped with a contact sensor to detect the presence or absence of contact between the push device and the piston head.

10. Pump according to claim 7, wherein the the push device is driven by a threaded driving rod driven in rotation by a motor.

11. Pump according to claim 10, wherein the clutch comprises a clutch lever located outside the casing, a push rod integral with the lever and two half-nuts capable of being moved from an engaged position in which they surround the threaded driving rod so as to be capable of cooperating with it and a disengaged position in which they are moved away from the threaded driving rod so that they do not cooperate with it.

12. Pump according to claim 7, wherein at least one engagement sensor is provided to determine if the push device is engaged or disengaged on the clutch.

13. Pump according to claim 12, wherein the engagement sensor or sensors are placed on at least one of (i) the push device and (ii) the clutch.

19. Pump according to claim 8, wherein the push device is equipped with a contact sensor to detect the presence or absence of contact between the push device and the piston head.

20. Pump according to claim 8, wherein the the push device is driven by a threaded driving rod driven in rotation by a motor.

21. Pump according to claim 11, wherein the push device comprises a force sensor that detects if the two half-nuts have not reached the engaged position when engaging the push device, so that the threaded driving rod is set in rotation by controlling the effort generated by the push device on the syringe via a force sensor integrated with the push device.

29. Pump according to claim 7, wherein the push device is being driven in translation by a motor.

30. Pump according to claim 7, wherein the push device is being driven in translation by driving means.

25. Method of controlling the movement of a push device of a pump of the syringe driver-type, the pump comprising a casing, a syringe cradle in which a syringe is placed, a push device mobile relative to the casing and capable of being driven in translation parallel to the longitudinal axis of the syringe, and a clutch having an engaged configuration engaging the push device to be driven in translation and a disengaged configuration disengaging the push device from being driven in translation, the push device being driven by a threaded driving rod by two haft-nuts capable of being moved between an engaged position in which the two half-nuts are brought close to each other and surrounding the threaded driving rod so that they can move on the threaded driving rod when the threaded driving rod is set in rotation, and a disengaged position in which the two half-nuts are brought a from each other and from the threaded driving rod so that they no longer cooperate with the driving rod, said method comprising:

a) setting the clutch in the disengaged configuration disengaging the push device;

b) detecting the presence or absence of contact between the push device and a piston head of the syringe;

b′

) detecting the presence of a contact between the push device and the piston head, and moving in translation, by the desired amplitude, the push device in contact with the piston head in the direction of the syringe;

b″

) stopping the movement of the push device and setting the clutch in the engaged configuration engaging the push device,

wherein the method comprises, in order to set the clutch in the engaged configuration in step b″

);

b′

″

) detecting the relative position of the half-nuts;

b″

″

l if the two half-nuts have not reached the engaged position, setting the threaded driving rod in rotation, until the two half-nuts have reached the engaged position.

26. Method according to claim 25, comprising the following additional step performed after step b″

);

b″

″

′

)driving the push device in translation.

27. Method according to claim 25, wherein the push device is being driven in translation by a motor.

28. Method according to claim 25, wherein the push device is being driven in translation by driving means.