Anti-PD-1 antibodies
First Claim
Patent Images
1. A method of treating cancer, comprising administering an antibody or antigen binding fragment to a patient suffering from a cancer, wherein the antibody or antigen binding fragment binds to PD-1, and comprises:
- at least one light chain variable region incorporating the following CDRs;
1 Assignment
0 Petitions
Accused Products
Abstract
Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
Citations
20 Claims
-
1. A method of treating cancer, comprising administering an antibody or antigen binding fragment to a patient suffering from a cancer, wherein the antibody or antigen binding fragment binds to PD-1, and comprises:
at least one light chain variable region incorporating the following CDRs; - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
-
9. A method of treating cancer, comprising administering an antibody or antigen binding fragment to a patient suffering from a cancer, wherein the antibody or antigen binding fragment binds to PD-1, and comprises:
-
a heavy chain variable region comprising the amino acid sequence of SEQ ID NO;
15, anda light chain variable region comprising the amino acid sequence of SEQ ID NO;
3. - View Dependent Claims (10, 11, 12, 13, 14)
-
-
15. A method of treating cancer in a subject, comprising:
-
culturing T cells obtained from a blood sample from a subject having a cancer in the presence of an antibody or antigen binding fragment which binds to PD-1 to expand a T cell population; and administering the expanded T cell population to the subject; wherein the antibody or antigen binding fragment which binds to PD-1 comprises; at least one light chain variable region incorporating the following CDRs; - View Dependent Claims (16, 17, 18, 19, 20)
-
Specification