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Piezoelectric scaffold for nerve growth and repair

  • US 9,771,557 B2
  • Filed: 04/21/2016
  • Issued: 09/26/2017
  • Est. Priority Date: 03/12/2009
  • Status: Active Grant
First Claim
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1. An electroactive structure for growing an isolated differentiable cell comprisinga three-dimensional matrix of electrospun fibers comprising a biocompatible synthetic permanently piezoelectric polymeric material, wherein the fibers are annealed, either thermally or chemically, and demonstrate enhanced piezoelectric characteristics, crystal organization or a combination of both, wherein the matrix forms a supporting scaffold for growing the differentiable cell, andat least one isolated differentiable neural progenitor cell seeded in the matrix.

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