High alcohol content sanitizer

• US 9,775,344 B2
• Filed: 10/19/2015
• Issued: 10/03/2017
• Est. Priority Date: 02/23/2011
• Status: Active Grant

• Current Assignee: Donald R. Korb
• Original Assignee: Donald R. Korb
• Inventors: Korb, Donald R., Bhargava, Hridaya N.
• Primary Examiner(s): Browe, David
• Application Number:
  US14/886,902
• Publication Number:
  US 20160081333A1
• Time in Patent Office: 715 Days
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/04 Dispersions, emulsions, suspoemulsions, suspension concentrates or gels foams A01N25/16
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A61K 2800/48 Thickener, Thickening system
• CPC Class Codes: A61K 2800/49 Solubiliser, Solubilising system
• CPC Class Codes: A61K 2800/596 Mixtures of surface active compounds
• CPC Class Codes: A61K 2800/74 Biological properties of particular ingredients
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/553 Phospholipids, e.g. lecithin
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/007 Preparations for dry skin

Abstract

An antimicrobial sanitizing composition in the form of a gel or cream containing an alcohol in an amount of at least 55% by weight. The sanitizer is capable of disinfecting a variety of surfaces, including the skin. In addition to alcohol, the sanitizer contains an anionic phospholipid in a controlled concentration as well as components conventionally found in skin creams and gels such as emulsifiers, emollients, moisturizers, rheology modifiers, and neutralizers.

Claims

1. A method for sanitizing skin, the method comprising:

applying a sanitizer to the skin in the form of a gel or a cream, the sanitizer having a pH of at least 6.8 and comprising;

at least 60 weight percent of a C1 to C4 alcohol;

a rheology modifier and optionally at least one emollient and/or at least one emulsifier, the rheology modifier being selected from the group consisting of carboxylic acid polymers, crosslinked polyacrylate polymers, polyacrylamide polymers, polysaccharides, and combinations thereof; and

an anionic phospholipid in an amount of at least 0.1 weight percent of the sanitizer.

2. The method of claim 1, wherein the anionic phospholipid is present in an amount of from 0.25 to 2.5 percent of the sanitizer.

3. The method of claim 1, wherein the anionic phospholipid is added as a component of a phospholipid mixture and is present in the phospholipid mixture in an amount of at least 5 weight percent of the total phospholipid content.

4. The method of claim 3, wherein the anionic phospholipid component is present in the phospholipid mixture in an amount of between 8 and 15 weight percent and the phospholipid mixture is free of cationic phospholipids.

5. The method of claim 3, wherein the anionic phospholipid is phosphatidylethanolamine.

6. The method of claim 1, wherein the emollient is present in the amount of from 1.0 to 8.0 weight percent of the sanitizer.

7. The method of claim 1, wherein the emulsifier is present in the amount of from 0.1 to 3.5 weight percent of the sanitizer.

8. The method of claim 1, wherein the rheology modifier is present in the amount of from 2.5 to 8.0 percent of the sanitizer.

9. The method of claim 1, wherein the rheology modifier is an acrylates copolymer.

10. A method of forming a sanitizer composition, the method comprising:

forming a sanitizer in the form of a gel or a cream, the forming the sanitizer comprising;

adding an anionic phospholipid to an alcohol to form a first mixture;

heating the first mixture to a temperature of 30°

C. to form a first homogeneous solution;

cooling the first homogeneous solution to room temperature;

adding a water soluble moisturizer to water to form a second homogeneous solution;

after the cooling, combining the first homogeneous solution, the second homogeneous solution, and a rheology modifier to form a second mixture, the rheology modifier being selected from the group consisting of carboxylic acid polymers, crosslinked polyacrylate polymers, polyacrylamide polymers, polysaccharides, and combinations thereof; and

agitating the second mixture to form the sanitizer, the sanitizer having a pH of at least 6.8, the alcohol being present in an amount of at least 55 percent by weight of the sanitizer, and the anionic phospholipid being present in an amount of at least 0.10 percent by weight of the sanitizer.

11. The method of claim 10, wherein the anionic phospholipid is present in an amount from 0.25 to 2.5 percent by weight of the sanitizer.

12. The method of claim 10, wherein the anionic phospholipid is added as a component of a phospholipid mixture and is present in the phospholipid mixture in an amount of at least 5 percent by weight of the phospholipid mixture.

13. The method of claim 12, wherein the phospholipid mixture is free of cationic phospholipids.

14. The method of claim 10, wherein the anionic phospholipid is phosphatidylethanolamine.

15. The method of claim 10, wherein the alcohol is present in an amount of at least 60 percent by weight of the sanitizer.

16. The method of claim 10, wherein the alcohol is a C1 to C4 alcohol and is present in an amount from 60 to 75 percent by weight of the sanitizer.

17. The method of claim 10, wherein the pH is from 7.0 to 8.0.

18. The method of claim 10, wherein the rheology modifier is present in an amount to provide a viscosity of at least 2,500 cps.

19. The method of claim 10, wherein the rheology modifier is present in an amount of at least 2.5 percent by weight of the sanitizer.

20. The method of claim 10, wherein the rheology modifier is a crosslinked polyacrylate polymer present in an amount of from 2.5 to 8.0 weight percent of the sanitizer.

21. The method of claim 10 further comprising an emollient selected from the group consisting of oils, aloe, fatty esters, glycerol esters, propylene glycol esters, alkoxylated carboxylic acids, alkoxylated alcohols, fatty alcohols, fatty acids, and combinations thereof present in an amount of from 1.0 to 8.0 percent by weight of the sanitizer.

22. The method of claim 10 further comprising an emollient selected from the group consisting of isopropyl-palmitate, isopropyl-myristate, aloe, and mixtures thereof and is present in an amount from 3.0 to 6.0 percent by weight of the sanitizer.

23. The method of claim 10, wherein the rheology modifier is an acrylates copolymer.

24. A method of forming a sanitizing composition, the method comprising:

forming a sanitizing composition, the forming the sanitizing composition comprising;

mixing a phospholipid mixture, an emollient, an emulsifier, and one or more alcohols having from 1 to 4 carbon atoms to form a first mixture;

heating the first mixture to 30°

C. to form a first homogeneous mixture;

the phospholipid mixture comprising an anionic phospholipid;

the emollient being selected from the group consisting of oils, aloe, fatty esters, glycerol esters, propylene glycol esters, alkoxylated carboxylic acids, alkoxylated alcohols, fatty alcohols, fatty acids, and combinations thereof;

the emulsifier being selected from the group consisting of esters of glycerin, esters of propylene glycol, fatty acid esters of polyethylene glycol, fatty acid esters of polypropylene glycol, esters of sorbitol, esters of sorbitan anhydrides, carboxylic acid copolymers, esters and ethers of glucose, ethoxylated ethers, ethoxylated alcohols, alkyl phosphates, polyoxyethylene fatty ether phosphates, fatty acid amides, acyl lactylates, soaps, triethanolamine (TEA) stearate, diethanolamine (DEA) oleth-3 phosphate, polyethylene glycol 20 sorbitan monolaurate (polysorbate

     20), sorbitan monostearate (Span

     60), polyethylene glycol (PEG) 5 soya sterol, steareth-2, steareth-20, steareth-21, ceteareth-20, polypropylene glycol 2 (PPG-2) methyl glucose ether distearate, ceteth-10, polysorbate 80, cetyl phosphate, potassium cetyl phosphate, diethanolamine cetyl phosphate, polysorbate 60, glyceryl stearate, PEG-100 stearate, and combinations thereof;

cooling the first homogeneous mixture to room temperature;

mixing a water soluble moisturizer with water to form a second homogeneous mixture;

adding the second homogeneous mixture and a rheology modifier to the first homogeneous mixture to form the sanitizing composition;

the rheology modifier being selected from the group consisting of carboxylic acid polymers, crosslinked polyacrylate polymers, polyacrylamide polymers, polysaccharides, and combinations thereof;

the one or more alcohols being present in an amount of at least 55 percent by weight of the sanitizing composition;

the phospholipid mixture being present in an amount of at least 1 percent by weight of the sanitizing composition;

the emollient being present in an amount from 1 percent to 8 percent by weight of the sanitizing composition;

the rheology modifier being present in an amount from 2.5 percent to 8.0 percent by weight of the sanitizing composition; and

the emulsifier being present in an amount from 0.1 percent to 3.5 percent by weight of the sanitizing composition.

25. The method of claim 24, wherein the anionic phospholipid is selected from the group consisting of phosphoglycerides, phosphatidylethanolamine, and combinations thereof.

26. The method of claim 24, wherein the rheology modifier is an acrylates copolymer.