Polymers and methods thereof for wound healing
First Claim
1. A therapeutic method for treating a wound, preventing fibrous adhesions at a wound site and/or providing localized analgesia at a wound site in an animal comprising administering to an animal in need of such therapy an effective amount of a copolymer having a backbone, wherein the backbone comprises a) one or more polyanhydride units that comprise a group that will yield a biologically active agent upon hydrolysis of the backbone;
- and b) one or more units of formula (II);
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Accused Products
Abstract
Certain embodiments of the invention provide a copolymer having a backbone, wherein the backbone comprises a) one or more units that comprise a group that will yield a biologically active agent upon hydrolysis of the backbone; and b) one or more units of formula (II):
wherein y is 1 or more. Other embodiments of the invention provide a therapeutic method for treating a wound in an animal comprising administering to an animal in need of such therapy, an effective amount of a copolymer as described herein.
125 Citations
17 Claims
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1. A therapeutic method for treating a wound, preventing fibrous adhesions at a wound site and/or providing localized analgesia at a wound site in an animal comprising administering to an animal in need of such therapy an effective amount of a copolymer having a backbone, wherein the backbone comprises a) one or more polyanhydride units that comprise a group that will yield a biologically active agent upon hydrolysis of the backbone;
- and b) one or more units of formula (II);
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
- and b) one or more units of formula (II);
-
16. A therapeutic method for preventing fibrous adhesions at a wound site in an animal comprising administering to an animal in need of such therapy an effective amount of a copolymer having a backbone, wherein the backbone comprises a) one or more polyanhydride units that comprise a group that will yield a biologically active agent upon hydrolysis of the backbone;
- and b) one or more units of formula (II);
- and b) one or more units of formula (II);
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17. A therapeutic method for preventing fibrous adhesions at a wound site in an animal comprising administering to an animal in need of such therapy an effective amount of a copolymer comprising one or more units of formula (IIIa):
Specification