Selective delivery molecules and methods of use
First Claim
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1. A selective delivery molecule having the structure of SDM-41:
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Abstract
Disclosed herein is a selective delivery molecule comprising: (a) an acidic sequence (portion A) which is effective to inhibit or prevent the uptake into cells or tissue retention, (b) a molecular transport or tissue retention sequence (portion B), and (c) a linker between portion A and portion B, and (d) cargo moieties (portion DA and DB).
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Citations
32 Claims
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1. A selective delivery molecule having the structure of SDM-41:
- 2. A tissue sample comprising a selective delivery molecule having the structure of SDM-41:
- 10. A method of delivering Cy5 and Cy7 to a tissue of interest, comprising contacting the tissue of interest with a selective delivery molecule having the structure of SDM-41:
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18. A method of visualizing a tissue of interest in an individual in need thereof, comprising:
(a) administering to the individual a selective delivery molecule having the structure of SDM-41; - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 30, 31, 32)
Specification