Implantable electrostimulator for improving blood flow

• US 9,782,589 B2
• Filed: 06/10/2015
• Issued: 10/10/2017
• Est. Priority Date: 06/10/2015
• Status: Active Grant

• Current Assignee: BlueWind Medical Ltd.
• Original Assignee: BlueWind Medical Ltd.
• Inventors: Oron, Gur, Gross, Yossi, Eytan, Bar, Benjamin, Eran, Aharonson-Raz, Karin, Plotkin, Anton
• Primary Examiner(s): Heller, Tammie K
• Application Number:
  US14/735,741
• Publication Number:
  US 20160361544A1
• Time in Patent Office: 853 Days
• Field of Search: 607 48
• CPC Class Codes: A61N 1/3606 adapted for a particular treatment
• CPC Class Codes: A61N 1/36135 using physiological parameters
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators
• CPC Class Codes: A61N 1/3787 from an external energy source

Abstract

An electrostimulator implant is percutaneously advanceable into tissue of a limb of a subject. The implant comprises (i) an intracorporeal sensor, configured to detect a factor indicative of local blood supply in the tissue of the limb; (ii) an electrode disposed at an outer surface of the implant; (iii) an antenna, configured to wirelessly receive power; and (iv) circuitry, powered by the received power, and configured to drive the electrode to apply a bloodflow-increasing current to the tissue at least in part responsively to the detected factor. Other embodiments are also described.

Claims

1. Apparatus, comprising:

an electrostimulator-implant, percutaneously advanceable into tissue of a limb of a subject, and comprising;

a temperature sensor, configured to detect a temperature of the tissue;

an electrode disposed at an outer surface of the implant;

an antenna, configured to wirelessly receive power; and

circuitry, powered by the received power, and configured to drive the electrode to apply a bloodflow-increasing current to the tissue at least in part responsively to the detected temperature; and

an extracorporeal device, attachable to the limb, and configured to wirelessly transmit the power received by the antenna,

wherein;

the extracorporeal device is configured to alternate between a first mode and a second mode,

in the first mode, the extracorporeal device is configured to wirelessly drive the circuitry to drive the electrode to apply the bloodflow-increasing current at a frequency of 1-100 Hz, and

in the second mode, the extracorporeal device is configured to wirelessly drive the circuitry to apply a second electrical current having a frequency of 1-10 kHz.

2. The apparatus according to claim 1, wherein the circuitry is configured to drive the electrode to apply the bloodflow-increasing current in response to the detected temperature being below a threshold temperature.

3. The apparatus according to claim 1, wherein the extracorporeal device is configured:

to receive from the implant information regarding the detected temperature, and

at least in part responsively to the received information, to wirelessly drive the circuitry to drive the electrode to apply the bloodflow-increasing current.

4. The apparatus according to claim 1, wherein the temperature sensor is a first temperature sensor, the extracorporeal device comprises a second temperature sensor, and the extracorporeal device is configured to wirelessly drive the circuitry to drive the electrode to apply the bloodflow-increasing current to the tissue, at least in part responsively to (i) the temperature detected by the first temperature sensor, and (ii) a temperature detected by the second temperature sensor.

5. The apparatus according to claim 1, wherein the implant further comprises a pressure sensor, configured to detect a pressure within the tissue, and the circuitry is configured to drive the electrode to apply the bloodflow-increasing current at least in part responsively to the detected pressure.

6. The apparatus according to claim 5, wherein the pressure comprises a pulse pressure, and the circuitry is configured to drive the electrode to apply the bloodflow-increasing current at least in part responsively to the detected pulse pressure.