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Method and system for non-invasive optical blood glucose detection utilizing spectral data analysis

  • US 9,788,764 B2
  • Filed: 09/11/2012
  • Issued: 10/17/2017
  • Est. Priority Date: 05/22/2008
  • Status: Active Grant
First Claim
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1. A system for detecting glucose in a biological sample, comprising:

  • at least one light beam generating structure generating one or more light beams having a wavelength in a range between 800 nm and 1600 nm to strike a target area of a biological sample;

    at least one photocurrent signal generating light detector containing one or more photodiodes positioned to receive detected blood glucose level information in the one or more light beams and to transform the detected blood glucose level information in the one or more light beams to the detected blood glucose level information in an output photocurrent signal, having a time dependent current, which is indicative of the power of light detected; and

    a blood glucose level caused light absorbance change determining algorithm implemented processor programmed to calculate a change in a light absorption caused by blood in the biological sample and configured to receive the output photocurrent signal from the at least one light detector and based on the received output photocurrent signal, calculate attenuance attributable to blood in a sample present in the target area and eliminate effect of uncertainty caused by temperature dependent detector response of the at least one light detector by calculating standard deviation of a logarithm of the time dependent output current generated by the light power from the same target area of the biological sample, and based on the calculated attenuance, determine a blood glucose level associated with a sample present in the target area.

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