Method and system to identify motion artifacts and improve reliability of measurements and alarms in photoplethysmographic measurements

• US 9,788,793 B2
• Filed: 07/22/2013
• Issued: 10/17/2017
• Est. Priority Date: 08/01/2012
• Status: Active Grant

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Koninklijke Philips N.V.
• Inventors: Zong, Wei, Wiggins, Dale, Gross, Brian David, Nielsen, Larry
• Primary Examiner(s): Heller, Tammie K
• Application Number:
  US14/417,275
• Publication Number:
  US 20150190096A1
• Time in Patent Office: 1,548 Days
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02125 of pulse wave propagation time
• CPC Class Codes: A61B 5/02405 Determining heart rate variability
• CPC Class Codes: A61B 5/02416 using photoplethysmograph signals, e.g. generated by infrared radiation A61B5/14552 takes precedence
• CPC Class Codes: A61B 5/11 Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb for measuring pulse A61B5/02 ;A61B5/1038 takes precedence; motion detection to correct for motion artifacts in physiological signals A61B5/721
• CPC Class Codes: A61B 5/1122 of movement trajectories
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14535 for measuring haematocrit
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/721 using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
• CPC Class Codes: A61B 5/7425 Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image geometric transforms for image registration G06T3/14; enhancement using image fusion G06T5/50; algorithms for registration of images G06T7/30
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: G01P 15/00 Measuring acceleration; Measuring deceleration; Measuring shock, i.e. sudden change of acceleration

Abstract

A system (10) and method to identify motion artifacts. Measurements of a physiological parameter of an associated patient are received from a probe (12) positioned on or proximate to the associated patient. Further, measurements of acceleration are received from an accelerometer (26) positioned on, proximate to, or integrated with the probe (12). Measurements of the physiological parameter are labeled based on the measured acceleration, such as being with or without motion.

Claims

1. A system for identifying motion artifacts, said system comprising:

a probe configured to sense a physiological parameter of an associated patient, the probe configured to be positioned on or proximate to the associated patient, the probe being configured to generate one or more physiological signals indicative of the sensed physiological parameter;

an accelerometer configured to be positioned on, proximate to, or integrated with the probe, the accelerometer configured to generate one or more acceleration signals measuring acceleration;

a first signal processing unit configured to process the one or more physiological signals from the probe to determine measurements of the physiological parameter;

a second signal processing unit configured to process one or more acceleration signals from the accelerometer to determine motion characteristics, the processing of the second signal processing unit being performed in parallel, and independent of, the processing of the first signal processing unit; and

a labeling unit configured to label measurement of the physiological parameter with temporally corresponding motion characteristics based on the determined motion characteristics; and

a signal quality index (SQI) threshold unit configured to discard or down weight measurements of the physiological parameter with signal quality indices (SQI)s below a SQI threshold and passing a remaining or down weighted measurements of the physiological parameter to the labeling unit; and

wherein the SQI threshold unit is configured to determine the SQI threshold by;

determining whether there is motion based on the measured acceleration;

in response to determining there is no motion, setting the SQI threshold to a predetermined value;

in response to determining there is motion, determining whether the motion is correlated with a measured motion artifact of the one or more physiological signals that is generated by, and received from, the probe;

in response to determining the motion is correlated, setting the SQI threshold to a first value using a correlated lookup function of a motion strength value; and

in response to determining the motion is uncorrelated, setting the SQI threshold to a second value using an uncorrelated lookup function of the motion strength value.

2. The system according to claim 1, wherein the second signal processing unit is further configured to generate a motion information signal (MIS) from the determined motion characteristics, an amplitude of the MIS corresponding to the measured acceleration.

3. The system according to claim 2, wherein the second signal processing unit is further configured to generate the MIS to include at least one of:

digital messages indicating at least one of movement speed, acceleration, direction, and duration; and

digital messages that each identify a start and end time for a period of movement.

4. The system according to claim 1, further including:

an alarm unit configured to generate alarms based on the measurements of the physiological parameter labeled with temporally corresponding motion characteristics that are indicative of acceptable motion characteristics.

5. The system according to claim 4, wherein the alarm unit is configured to disable the generation of alarms for a predetermined period of time in response to motion characteristics indicative of a motion indication signal (MIS) exceeding a predetermined threshold.

6. The system according to claim 5, wherein the accelerometer is configured to measure acceleration in three-dimensions and the MIS signal is indicative of translation along and rotation around each axis.

7. The system according to claim 1, further including:

a display device configured to display measurements of the physiological parameter and a visual representation of a motion indication signal (MIS).

8. The system according to claim 7, wherein the physiological parameter is one of oxygen saturation (SpO2), pulse rate (PR), percent saturated carboxyhemoglobin (SpCO), pulse pressure variation (PPV), pulse transient time (PPT), hemoglobin (HB), hemocrit (HCT), glucose (GLU), and cholesterol (CHOL).

9. The system according to claim 1, further including:

a selection unit configured to discard measurements of the physiological parameter labeled with unacceptable motion characteristics.

10. A method for identifying motion artifacts, said method comprising:

receiving, by at least one processor, one or more physiological signals of a sensed physiological parameter of an associated patient from a probe configured to be positioned on or proximate to the associated patient;

receiving, by the at least one processor, one or more acceleration signals measuring acceleration from an accelerometer positioned on, proximate to, or integrated with the probe;

processing the one or more physiological signals received from the probe to determine measurements of the physiological parameter;

processing the one or more signals from the accelerometer to determine motion characteristics, the processing of the one or more physiological signals being performed in parallel, and independent of, the processing of the one or more acceleration signals;

labeling, by the at least one processor, measurements of the physiological parameter with temporally corresponding motion characteristics based on the determined motion characteristics; and

generating, with the at least one processor, a signal quality index (SQI) of the measured physiological parameter by operations including

determining whether there is motion based on the measured acceleration;

in response to determining there is no motion, setting (SQI) threshold to a predetermined value;

in response to determining there is motion, determining whether the motion is correlated with a measured motion artifact of the one or more physiological signals that is generated by, and received from, the probe;

in response to determining the motion is correlated, setting the SQI threshold to a first value using a correlated lookup function of a motion strength value; and

,

in response to determining the motion is uncorrelated, setting the SQI threshold to a second value using an uncorrelated lookup function of the motion strength value.

11. The method according to claim 10, further including:

displaying measurements of the physiological parameter and a visual representation of a motion indication signal (MIS).

12. The method according to claim 10, wherein the physiological parameter is one of oxygen saturation (SpO2), pulse rate (PR), percent saturated carboxyhemoglobin (SpCO), pulse pressure variation (PPV), pulse transient time (PPT), hemoglobin (HB), hemocrit (HCT), glucose (GLU), and cholesterol (CHOL).

13. The method according to claim 10, further including at least one of:

generating a motion information signal (MIS) from the determined motion characteristics, an amplitude of the MIS corresponding to the measured acceleration; and

generating the MIS to include digital messages indicating at least one of movement speed, acceleration, direction, and duration.

14. The method according to claim 13, further including:

generating alarms based on the measurements of the physiological parameter labeled with temporally corresponding motion characteristics that are indicative of acceptable motion characteristics; and

disabling of alarms for a predetermined period of time in response to the motion characteristics indicative of the MIS exceeding a predetermined threshold.

15. The method according to claim 14, further including:

discarding measurements of the physiological parameter that are labeled as not being indicative of acceptable motion characteristics.

16. A system for identifying motion artifacts, said system comprising:

at least one processor programmed to;

receive measurements of a physiological parameter of an associated patient from an associated probe configured to be positioned on or proximate to the associated patient;

receive measurements of acceleration from an associated accelerometer positioned on, proximate to, or integrated with the probe;

label measurements of the physiological parameter as being with or without motion based on a measured acceleration threshold; and

discard or down weight measurements of the physiological parameter with signal quality indices (SQI)s below a SQI threshold, the at least one processor being programmed to determine the signal quality index threshold by;

determining whether there is motion based on the measured acceleration;

in response to determining there is no motion, setting the SQI threshold to a predetermined value;

in response to determining there is motion, determining whether the motion is correlated with a measured motion artifact of the one or more physiological signals that is generated by, and received from, the probe;

in response to determining the motion is correlated, setting the SQI threshold to a first value using a correlated lookup function of a motion strength value; and

in response to determining the motion is uncorrelated, setting the SQI threshold to a second value using an uncorrelated lookup function of the motion strength value.

17. The system according to claim 16, further including:

a probe configured to sense the physiological parameter of the associated patient, the probe being configured to generate one or more physiological signals indicative of the sensed physiological parameter;

an accelerometer configured to be positioned on, proximate to, or integrated with the probe, the accelerometer configured to generate one or more acceleration signals measuring acceleration; and

wherein the at least one processor is further programmed to;

process the one or more physiological signals from the probe to determine measurements of the physiological parameter;

process one or more acceleration signals from the accelerometer to determine motion characteristics, the processing of the acceleration signals being performed in parallel, and independent of, the processing of the physiological signals; and

label measurements of the physiological parameter with temporally corresponding motion characteristics based on the determined motion characteristics.