Ambulatory lung assist device with implanted blood pump and oxygenator

• US 9,789,240 B2
• Filed: 01/28/2016
• Issued: 10/17/2017
• Est. Priority Date: 04/06/2012
• Status: Active Grant

• Current Assignee: Heartware,Inc. (Medtronic Plc)
• Original Assignee: Heartware,Inc. (Medtronic Plc)
• Inventors: Strueber, Martin
• Primary Examiner(s): Tejani, Ankit D
• Application Number:
  US15/008,653
• Publication Number:
  US 20160136347A1
• Time in Patent Office: 628 Days
• Field of Search: None
• CPC Class Codes: A61M 1/14 Dialysis systems; Artificial kidneys; Blood oxygenators semi-permeable membranes characterised by the material, manufacturing processes therefor B01D71/00 ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
• CPC Class Codes: A61M 1/1698 Blood oxygenators with or without heat-exchangers intracorporal A61M1/1678; manufacturing of membranes therefor B01D67/00; semi-permeable membranes for separation processes characterised by their properties B01D69/00; semi-permeable membranes characterised by their material B01D71/00
• CPC Class Codes: A61M 1/32 Oxygenators without membranes
• CPC Class Codes: A61M 1/3666 Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
• CPC Class Codes: A61M 1/3667 with assisted venous return
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/216 including a rotating member acting on the blood, e.g. impeller
• CPC Class Codes: A61M 60/38 Blood oxygenation

Abstract

The present disclosure provides a system for oxygenating blood. The system may include an implantable blood pump that may draw a supply of blood from the circulatory system of a mammalian subject, such as a human being. The blood pump may provide the supply of blood to an adaptor, where the supply of blood may be supplied to either or both of a first branch or second branch. The first branch may lead to an external blood oxygenator. The oxygenator may oxygenate the blood, and the blood may be returned to the circulatory system of the mammalian subject. The second branch may bypass the oxygenator and may connect to the circulatory system of the mammalian subject. In this regard, while the blood is supplied to the second branch, the oxygenator may be disconnected and blood may be prevented from entering the first branch.

Claims

1. A portable lung assist system comprising:

a blood pump having a pump outlet and a pump inlet configured for communication with a circulatory system of a mammalian subject at an inlet location, the blood pump being carriable by the mammalian subject;

an external, portable blood oxygenator for supplementing an action of the mammalian subject'"'"'s lungs having a blood inlet releasably connectable to the pump outlet and a blood outlet releasably connectable to the circulatory system of the mammalian subject at a return location; and

a bypass conduit connectable to the pump outlet and to the circulatory system at the return location.

2. The system of claim 1, wherein the blood inlet and the blood outlet are releasably connectable while the blood pump and the bypass conduit are connected to the circulatory system.

3. The system of claim 1, further comprising a first return fitting and a second return fitting adapted for connection to the circulatory system at the return location and adapted for respective connection to the blood outlet and the bypass conduit.

4. The system of claim 1, wherein the inlet location and the return location are located within a same anatomical feature of the circulatory system.

5. The system of claim 4, wherein the anatomical feature of the circulatory system is a pulmonary artery.

6. The system of claim 4, wherein the anatomical feature of the circulatory system is a right atrium.

7. The system of claim 4, wherein the anatomical feature of the circulatory system is a right ventricle.

8. The system of claim 1, further comprising a dual-lumen catheter having a first lumen and a second lumen, the first lumen comprising a system inlet fitting, and the second lumen comprising a system return fitting.

9. A portable lung assist system comprising:

a system inlet and a system return connectable to a circulatory system of a mammalian subject at an inlet location and a return location thereof, respectively;

a blood pump having a pump inlet in communication with the system inlet and a pump outlet;

a blood bypass having a bypass inlet in communication with the pump outlet, a bypass outlet in communication with the system return, and at least one conduit disposed between the bypass inlet and the bypass outlet and in communication therewith; and

a portable blood oxygenator having a blood inlet in communication with the pump outlet and a blood outlet in communication with the system return, the portable blood oxygenator being disconnectable from the lung assist system at a plurality of disconnect locations located downstream of the blood outlet and upstream of the blood inlet.

10. The system of claim 9, wherein the portable blood oxygenator is disconnectable from the lung assist system via a plurality of disconnect fittings located at the plurality of disconnect locations, and when the portable blood oxygenator is disconnected from the lung assist system, the blood pump continuously supplies blood to the blood bypass.

11. The system of claim 9, wherein the system return comprises a first return fitting and a second return fitting adapted for connection to the circulatory system, and the bypass outlet is in communication with the first return fitting and the blood outlet is in communication with the second return fitting.

12. The system of claim 9, wherein the system return includes a return fitting adapted for connection to the circulatory system, and the bypass outlet and the blood outlet are both in communication with the return fitting.

13. The system of claim 9, wherein the blood bypass includes an additional blood oxygenator connected thereto between the bypass inlet and the bypass outlet.

14. The system of claim 9, wherein the inlet location and the return location are located within a same anatomical feature of the circulatory system.

15. The system of claim 14, wherein the anatomical feature of the circulatory system is a pulmonary artery.

16. The system of claim 14, wherein the anatomical feature of the circulatory system is a right atrium.

17. The system of claim 14, wherein the anatomical feature of the circulatory system is a right ventricle.

18. The system of claim 14, further comprising a dual-lumen catheter having a first lumen and a second lumen, the first lumen including an inlet fitting and the second lumen including a return fitting.

19. A method of providing respiratory assistance to a subject comprising:

directing blood from a system inlet at an inlet location within a circulatory system of the subject through a blood pump, out of the subject, through a portable oxygenator and back to the circulatory system through a return at a return location within the circulatory system;

disconnecting the portable oxygenator;

directing blood through the blood pump, through a blood bypass and back to the circulatory system through the return at the return location; and

reconnecting either the portable oxygenator or a different portable oxygenator.

20. The method of claim 19, wherein the inlet location and the return location are both located at one of a right atrium, a right ventricle or a pulmonary artery of the circulatory system.

21. The method of claim 19, further comprising a dual-lumen catheter having a first lumen including an inlet fitting, and a second lumen including a return fitting.