Active catheter device and associated system and method

• US 9,789,286 B2
• Filed: 03/16/2016
• Issued: 10/17/2017
• Est. Priority Date: 03/28/2011
• Status: Active Grant

• Current Assignee: North Carolina State University (University of North Carolina System)
• Original Assignee: North Carolina State University (University of North Carolina System)
• Inventors: Buckner, Gregory Dale, Veeramani, Arun Shankar, Owen, Stephen B., Jernigan, Shaphan R.
• Primary Examiner(s): Jackson, Gary
• Assistant Examiner(s): LUAN, SCOTT
• Application Number:
  US15/071,701
• Publication Number:
  US 20160361518A1
• Time in Patent Office: 580 Days
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2017/00867 shape memory effect
• CPC Class Codes: A61B 2018/00011 with fluids
• CPC Class Codes: A61B 2090/065 for measuring contact or contact pressure
• CPC Class Codes: A61M 2205/0266 Shape memory materials
• CPC Class Codes: A61M 25/0105 Steering means as part of the catheter or advancing means; Markers for positioning systems for detection of markers A61B
• CPC Class Codes: A61M 25/0147 with movable mechanical means, e.g. pull wires
• CPC Class Codes: A61M 25/0158 with magnetic or electrical means, e.g. by using piezo materials, electroactive polymers, magnetic materials or by heating of shape memory materials

Abstract

An active catheter device is provided. At least one elongate catheter segment includes an elongate flexible tube member defining an axis, and a pair of ferrule members operably engaged with and spaced apart along the tube member. The ferrule members are not rotatable about the axis relative to each other. At least one articulation member is operably engaged with and extends at least between the ferrule members along the tube member. Each articulation member is configured to be actuatable to cause a change in a distance between the ferrule members so as to articulate the tube member. Associated systems and methods are also provided.

Claims

1. An active catheter device, comprising:

an elongate catheter having multiple segments, including;

an elongate flexible tube member defining an axis;

a plurality of ferrule members operably engaged with the tube member, in successive spaced apart relation with respect to each other, such that the ferrule members are positioned at the ends of each segment and are not rotatable about the axis relative to each other; and

at least one articulation member operably engaged with and extending between adjacent ferrule members of a first segment along the tube member configured to be actuatable to cause a change in a distance between the adjacent ferrule members so as to articulate the first segment of the tube member; and

at least one articulation member operably engaged with and extending between a pair of non-adjacent ferrule members spanning more than one segment, including spanning the first segment and an adjacent segment, the tube member configured to be actuatable to cause a change in a distance between the pair of non-adjacent ferrule members so as to articulate the segments, including further articulation of the first segment.

2. The device according to claim 1, wherein each articulation member is comprised of a superelastic material configured to undergo a material phase change from an unactuated configuration to an actuated configuration upon the application of a stimulus and thereby causes the distance between the ferrule members to change and the tube member to substantially conform thereto.

3. The device according to claim 2, wherein the superelastic material comprises a nickel-titanium alloy.

4. The device according to claim 2, further comprising a controller having a processor and being in communication with a stimulus generator operably engaged with the articulation members, the stimulus generator generating and applying the stimulus to the articulation members to cause heating thereof, in response to direction from the controller.

5. The device according to claim 4, wherein the stimulus generator generates and selectively applies the stimulus to individual articulation members, in response to direction from the controller.

6. The device according to claim 4, wherein the controller is configured as an axial advancement controller in communication with the catheter device, the axial advancement controller determining a threading configuration of the multiple segments of the catheter device in response to axial advancement of the catheter device.

7. The device according to claim 6, wherein the axial advancement controller is in communication with a user input device, the axial advancement controller controlling and guiding the catheter device in a “

snake”

or “

serpentine”

type manner as the catheter device is axially-advanced into an anatomical pathway, in response to direction from the user input device.

8. The device according to claim 7, wherein the axial advancement controller and the user input device further cooperate with a feed drive mechanism to direct subsequent segments of the catheter device into a substantially similar configuration of the initial segment as the initial segment was advanced through that portion of the anatomical pathway.

9. The device according to claim 6, wherein the axial advancement controller in communication with the catheter device determines the threading configuration of the multiple segments of the catheter device in response to withdrawal of the catheter device from the anatomical pathway.

10. The device according to claim 2, further comprising a stimulus generator operably engaged with each of the articulation members, the stimulus generator applying the stimulus to each of the articulation members, wherein heat associated with the stimulus causes the material phase change in the superelastic material.

11. The device according to claim 1, further comprising at least one sensor disposed proximate to a leading end of the elongate flexible tube member, the at least one sensor being configured to determine a force applied about the leading end along the axis and to generate a signal corresponding thereto.

12. An active catheter system, comprising:

an elongate catheter device having multiple segments, including;

an elongate flexible tube member defining an axis;

a plurality of ferrule members operably engaged with the tube member, in successive spaced apart relation with respect to each other, such that the ferrule members are positioned at the ends of each segment and are not rotatable about the axis relative to each other;

at least one articulation member operably engaged with and extending between adjacent ferrule members of a first segment along the tube member;

at least one articulation member operably engaged with and extending between a pair of non-adjacent ferrule members spanning more than one segment, including spanning the first segment and an adjacent segment;

wherein each articulation member being comprised of a superelastic material configured to undergo a material phase change from an unactuated configuration to an actuated configuration upon the application of a stimulus; and

a controller having a processor and being in communication with a stimulus generator operably engaged with the articulation members of the first segment and articulation members of the more than one segment, the stimulus generator generating and selectively and discretely applying a stimulus individually to the articulation members such that the articulation members of the first segment and articulation members spanning the more than one segment change from the unactuated configuration to the actuated configuration in response to the respective selective stimulus, and thereby causes the tube member to substantially conform thereto.

13. The system according to claim 12, wherein the controller is configured as an axial advancement controller in communication with the catheter device, the axial advancement controller determining the configuration of the multiple segments of the catheter device as the catheter device is axially-advanced.

14. The system according to claim 13, further comprising a user input device in communication with the axial advancement controller, the axial advancement controller controlling and guiding the catheter device in a “

snake”

or “

serpentine”

type manner as the catheter device is axially-advanced into an anatomical pathway, in response to direction of the user input device.

15. The system according to claim 14, further comprising a feed drive mechanism, wherein the controller and the user input device further cooperate with the feed drive mechanism to direct subsequent segments of the catheter device into a substantially similar configuration of the initial segment as the initial segment was advanced through that portion of the anatomical pathway.

16. The system according to claim 13, wherein the axial advancement controller in communication with the catheter device determines the configuration of the multiple segments of the catheter device in response to withdrawal of the catheter device from the anatomical pathway.

17. The system according to claim 12, further comprising at least one sensor disposed proximate to a leading end of the elongate flexible tube member, the at least one sensor being configured to determine a force applied about the leading end along the axis and to generate a signal corresponding thereto.

18. An active catheter system adapted to be applied to an anatomical pathway, the active catheter system comprising:

an elongate catheter having multiple segments, including;

an elongate flexible tube member defining an axis and having a leading end and an opposed trailing end;

a plurality of ferrule members operably engaged with the tube member, in successive spaced apart relation with respect to each other, such that the ferrule members are positioned at the ends of each segment and are not rotatable about the axis relative to each other; and

at least one articulation member operably engaged with and extending between adjacent ferrule members of a first segment along the tube member configured to be actuatable to cause a change in a distance between the adjacent ferrule members so as to articulate the first segment of the tube member;

at least one articulation member operably engaged with and extending between a pair of non-adjacent ferrule members spanning more than one segment, including spanning the first segment and an adjacent segment, the tube member configured to be actuatable to cause a change in a distance between the pair of non-adjacent ferrule members so as to articulate the segments, including enhance the bending of the first segment; and

an axial advancement controller having a processor and being operably engaged with the articulation members, the axial advancement controller device determining a threading configuration of the multiple segments of the catheter device, in response to axial advancement of the catheter device.

19. The system according to claim 18, further comprising a user input device in communication with the axial advancement controller, the axial advancement controller controlling and guiding the catheter device in a “

snake”

or “

serpentine”

type manner as the catheter device is axially-advanced into an anatomical pathway.

20. The system according to claim 18, wherein each articulation member is comprised of a superelastic material configured to undergo a material phase change from an unactuated configuration to an actuated configuration upon the application of a stimulus;

and the axial advancement controller is in communication with a stimulus generator operably engaged with the articulation members, the stimulus generator generating and selectively and discretely applying a stimulus individually to each of the articulation members such that the articulation members changes from the unactuated configuration to the actuated configuration in response to the respective selective stimulus, and thereby causes the tube member to substantially conform to the threading configuration.