Optochemical sensor

• US 9,791,377 B2
• Filed: 10/15/2014
• Issued: 10/17/2017
• Est. Priority Date: 10/23/2013
• Status: Active Grant

• Current Assignee: Tecsense Gmbh
• Original Assignee: Tecsense Gmbh
• Inventors: Ribitsch, Volker, Krottmaier, Johannes
• Primary Examiner(s): GUNBERG, EDWIN C
• Application Number:
  US15/031,866
• Publication Number:
  US 20160266044A1
• Time in Patent Office: 1,098 Days
• Field of Search: None
• CPC Class Codes: G01J 3/0202 Mechanical elements; Supports for optical elements
• CPC Class Codes: G01J 3/0272 Handheld
• CPC Class Codes: G01J 3/0291 Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements
• CPC Class Codes: G01J 3/4406 Fluorescence spectrometry
• CPC Class Codes: G01N 2021/6419 Excitation at two or more wavelengths
• CPC Class Codes: G01N 2021/6432 Quenching
• CPC Class Codes: G01N 2021/6441 with two or more labels
• CPC Class Codes: G01N 2021/6484 Optical fibres
• CPC Class Codes: G01N 2021/7786 Fluorescence
• CPC Class Codes: G01N 2021/7793 Sensor comprising plural indicators
• CPC Class Codes: G01N 2021/7796 Special mountings, packaging of indicators
• CPC Class Codes: G01N 21/6428 Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" in vivo A61B5/00; immunoassay G01N33/53
• CPC Class Codes: G01N 21/643 non-biological material
• CPC Class Codes: G01N 21/645 Specially adapted constructive features of fluorimeters
• CPC Class Codes: G01N 21/77 by observing the effect on a chemical indicator
• CPC Class Codes: G01N 21/7703 using reagent-clad optical fibres or optical waveguides using measurement of total internal reflection or attenuated total reflection G01N21/552; optical fibres or waveguides per se G02B
• CPC Class Codes: G01N 2201/064 Stray light conditioning

Abstract

An optochemical sensor comprises a measuring element excitable by the light of an excitation light source and in contact with a medium to be measured, and a measuring arrangement including at least one excitation light source and a detector as well as a hood separating the measuring arrangement from the measuring element, wherein the excitation light source and the detector are fixed to a base plate arranged in parallel with the measuring element, the hood, the excitation light source and the detector are separated from one another by at least a portion of the material thickness of the hood, and light from the excitation light source through an optical waveguide impinges on the measuring element at such an angle that fluorescence light emitted by the measuring element impinges perpendicularly on the detector.

Claims

1. An optochemical sensor comprising a measuring element excitable by the light of an excitation light source and in contact with a medium to be measured, and a measuring arrangement including at least one excitation light source and a detector as well as a hood separating the measuring arrangement from the measuring element, wherein the excitation light source and the detector are fixed to a base plate arranged in parallel with the measuring element, that the excitation light source and the detector are separated from each other by at least a portion of the material thickness of the hood, that light from the excitation light source through an optical waveguide impinges on the measuring element at such an angle that fluorescence light emitted by the measuring element impinges perpendicularly on the detector, that a reference light source is disposed on the base plate at a distance from the excitation light source and the detector, that the excitation light source, the detector and the reference light source are arranged on one axis, and that the hood is detachably fixed to the base plate.

2. The optochemical sensor according to claim 1, wherein the excitation light source is embedded in the material thickness of the hood.

3. The optochemical sensor according to claim 1, wherein a portion of the hood located between the excitation light source and the measuring element comprises a smoothened surface and is designed as an optical waveguide.

4. The optochemical sensor according to claim 1, wherein the measuring element is directly applied to an end portion of the fiber-optic elements forming the optical waveguide, and that the hood is at least partially comprised of glass and/or of polycarbonate containing glass fibers.

5. The optochemical sensor according to claim 1, wherein an inner surface of the hood is designed as, or comprises, a unidirectional radiation barrier.

6. The optochemical sensor according to claim 5, wherein the inner surface of the hood is mirrored or comprises a vaporized layer totally reflecting the light from the reference light source.

7. The optochemical sensor according to claim 1, wherein the hood, in the region of the measuring element, is formed with a roughened outer surface permeable to fluorescence light.

8. The optochemical sensor according to claim 1, wherein the measuring element is comprised of a base material capable of being cross-linked with a material of the hood and containing a fluorophore, in particular in the dissolved state.

9. The optochemical sensor according to claim 1, wherein the base material of the measuring element is selected from silicic acid ethyl ester or tetraethyl orthosilicate.

10. The optochemical sensor according to claim 1, wherein the measuring element is designed as a divided measuring element comprising two fluorophores optionally differing from each other.

11. The optochemical sensor according to claim 10, wherein the divided measuring element is excitable by two different excitation light sources.

12. The optochemical sensor according to claim 1, wherein a plurality of identical or different optochemical sensors are arranged on a base plate.

13. The optochemical sensor according to claim 1, wherein the base plate is comprised of a printed circuit board.