Medical device for modification of left atrial appendage and related systems and methods

• US 9,795,387 B2
• Filed: 09/16/2014
• Issued: 10/24/2017
• Est. Priority Date: 05/19/1997
• Status: Active Grant

• Current Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Original Assignee: Coherex Medical, Inc. (Johnson & Johnson)
• Inventors: Miles, Scott D., Linder, Richard J., Davis, Clark C., Whisenant, Brian K., Edmiston, Daryl R., Fox, DeWayne C.
• Primary Examiner(s): ANDERSON, GREGORY A
• Application Number:
  US14/487,885
• Publication Number:
  US 20150066074A1
• Time in Patent Office: 1,134 Days
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12159 Solid plugs; being solid before insertion
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00898 expandable upon contact with fluid
• CPC Class Codes: A61B 2017/0412 having anchoring barbs or pins extending outwardly from suture anchor body
• CPC Class Codes: A61B 2017/0427 having anchoring barbs or pins extending outwardly from the anchor body
• CPC Class Codes: A61B 2017/0649 Coils or spirals
• CPC Class Codes: A61B 2017/1205 Introduction devices

Abstract

Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a medical device includes a frame member and a tissue growth member. The frame member includes a unitary, seamless central portion having a plurality of struts defining a multi-cellular structure and an anchoring system, the plurality of struts extending between and configured to self-expand and directly bias the anchor system to anchor the frame member at least partially within the LAA. With this arrangement, the tissue growth member is attached to the frame member to occlude the LAA.

Claims

1. A medical device for modifying a left atrial appendage (LAA), comprising:

a frame member including distal anchor members for anchoring the frame member within the LAA, the frame member including a unitary, seamless central portion having a plurality of struts defining a multi-cellular structure extending between and configured to self-expand and directly bias the distal anchor members against a wall in the LAA, the plurality of struts and the distal anchor members extending in a common plane; and

a tissue growth member attached to the frame member and configured to occlude an opening of the LAA;

wherein the distal anchor members comprise first and second distal anchor members extending in a first plane and third and fourth distal anchor members extending in a second plane, the first plane transverse to the second plane.

2. The medical device of claim 1, wherein the distal anchor members comprise a first distal anchor portion and a second distal anchor portion with the central portion extending therebetween.

3. The medical device of claim 1, wherein the distal anchor members comprise tines extending therefrom for engaging the wall in the LAA.

4. The medical device of claim 1, wherein the frame member comprises proximal anchor members extending from the central portion.

5. The medical device of claim 4, wherein the tissue growth member is directly attached to the proximal anchor members.

6. The medical device of claim 1, wherein the multi-cellular structure of the central portion extends with a substantially flat configuration.

7. The medical device of claim 6, wherein the tissue growth member comprises a polymeric substrate.

8. A medical device for modifying a left atrial appendage (LAA), comprising:

a frame member including a central portion having a plurality of struts defining a multi-cellular structure and an anchoring system, the plurality of struts and the anchoring system extending in a common plane, the plurality of struts extending between and configured to self-expand and directly bias the anchor system to anchor the frame member at least partially within the LAA; and

a tissue growth member attached to the frame member;

wherein the anchoring system comprises;

a first distal anchor and a second distal anchor, the first distal anchor being co-planar with the second distal anchor; and

a third distal anchor and a fourth distal anchor, the third distal anchor being co-planar with the fourth distal anchor, the first distal anchor extending in a discrete plane relative the third distal anchor.

9. The medical device of claim 8, wherein the multi-cellular structure of the central portion extends with a substantially flat configuration.

10. The medical device of claim 8, wherein the frame member comprises proximal anchor members extending from the central portion.

11. The medical device of claim 10, wherein the tissue growth member is attached to the proximal anchor members.

12. The medical device of claim 8, wherein the distal anchor members comprise tines extending therefrom for engaging the wall in the LAA.

13. The medical device of claim 8, wherein the central portion is a unitary and seamless structure.