Reconfiguring tissue features of a heart annulus

• US 9,795,480 B2
• Filed: 12/11/2014
• Issued: 10/24/2017
• Est. Priority Date: 08/24/2010
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Millipede, Inc. (Boston Scientific Corporation)
• Inventors: Bolling, Steven F., Abbs, Jeremy A., Biancucci, Brian A.
• Primary Examiner(s): Tyson, Melanie
• Application Number:
  US14/567,872
• Publication Number:
  US 20150142105A1
• Time in Patent Office: 1,048 Days
• CPC Class Codes: A61F 2/243 Deployment by mechanical expansion
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus
• CPC Class Codes: A61F 2/2466 Delivery devices therefor
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2230/0069 cylindrical

Abstract

Among other things, a tool to attach a support to a heart valve annulus includes a stabilizing body that includes features to stabilize an axial position of the tool relative to the annulus, and an attachment device connected to the stabilizing body, the stabilizing body and the attachment device being movable relative to one another under control from a location remote from the tool. The support may have an expandable tubular body having a plurality of struts, a plurality of tissue anchors extending from distally facing apexes in a distal direction post-deployment, wherein axial distal advance of the implantable annulus support causes the plurality of tissue anchors to axially engage tissue, and the implantable annulus support is self-contractible from a radially enlarged engagement configuration for engaging tissue of the mitral valve annulus, to a reduced, deployed configuration for modifying mitral valve annulus geometry.

Claims

1. An implantable annulus support for modifying a mitral valve annulus from within a left atrium, comprising:

an expandable tubular body having a proximal end, a distal end, a sidewall therebetween and a longitudinal axis, the sidewall comprising a plurality of struts defining a plurality of distally facing apexes, the plurality of struts including a strut segment inclined radially outward away from the longitudinal axis in a distal direction, the tubular body expandable to a radially enlarged engagement configuration having a first width sufficient to span the mitral valve annulus; and

a plurality of tissue anchors extending in a distal direction from the distally facing apexes, wherein the plurality of tissue anchors extend in the distal direction at least after deployment from a sheath, wherein axial distal advance of the plurality of tissue anchors causes the plurality of tissue anchors to axially engage tissue;

wherein the implantable annulus support is contractible using a delivery tool from the radially enlarged engagement configuration for engaging tissue of the mitral valve annulus, to a reduced, deployed configuration for modifying mitral valve annulus geometry, and

wherein reducing an angle between at least two adjacent struts of the plurality of struts contracts the implantable annulus support and wherein increasing the angle expands the implantable annulus support.

2. An implantable annulus support as in claim 1, wherein the plurality of struts form zig zag shaped sections.

3. An implantable annulus support as in claim 1, wherein the plurality of struts are cut from a tube.

4. An implantable annulus support as in claim 3, wherein the plurality of struts are laser cut from the tube.

5. An implantable annulus support as in claim 1, wherein the sidewall comprises a shape memory material.

6. An implantable annulus support as in claim 1, wherein the sidewall comprises Nitinol.

7. An implantable annulus support as in claim 1, comprising a plurality of barbs on the tissue anchors.

8. An implantable annulus support as in claim 1, wherein the first width is 38 millimeters or more.

9. An implantable annulus support as in claim 1, wherein, in the reduced, deployed configuration, the implantable annulus support contracts to 6.5 millimeters.

10. An implantable annulus support as in claim 1, wherein the implantable annulus support in the reduced, deployed configuration has a second width, wherein the implantable annulus support is configured to be delivered in a delivery configuration, wherein the implantable annulus support in the delivery configuration has a third width, and wherein the first width is greater than the second width and the second width is greater than the third width.