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Methods of drying sheets of donor-provided human birth tissue

  • US 9,795,707 B2
  • Filed: 12/05/2014
  • Issued: 10/24/2017
  • Est. Priority Date: 12/06/2013
  • Status: Active Grant
First Claim
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1. A method of processing an amniotic tissue for administration to a recipient patient, comprising the steps oftreating the amniotic tissue with a glutaraldehyde solution;

  • rinsing the amniotic tissue with a first saline solution;

    contacting the amniotic tissue with a first backing layer and a second backing layer, wherein the amniotic tissue contains a second saline solution comprising a solvent and a dissociated salt;

    restraining the amniotic tissue and the first and second backing layers between a first plate and a second plate;

    pressing together the amniotic tissue and the first and second backing layers; and

    evaporating a portion of the solvent from a surface of the first or the second backing layer, so as to move a portion of the dissociated salt from the amniotic tissue into the first backing layer or the second backing layer, wherein;

    the second saline solution is formed in part by the first saline solution,evaporating comprises maintaining a temperature around the amniotic tissue at below about 40°

    C.,evaporating the portion of the solvent forms a processed amniotic tissue, andthe processed amniotic tissue is pliable.

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