Fluid delivery device needle retraction mechanisms, cartridges and expandable hydraulic fluid seals

• US 9,795,735 B2
• Filed: 04/23/2014
• Issued: 10/24/2017
• Est. Priority Date: 06/09/2010
• Status: Active Grant

• Current Assignee: Mannkind Corporation
• Original Assignee: Valeritas, Inc. (Zealand Pharma A/S)
• Inventors: Levesque, Steven F., Jenkins, Geoffrey H., Standley, Robert L., Johnson, Matthew P., Dube, Jr., Daniel A.
• Primary Examiner(s): FLICK, JASON E
• Application Number:
  US14/259,897
• Publication Number:
  US 20140236086A1
• Time in Patent Office: 1,280 Days
• Field of Search: 604150
• CPC Class Codes: A61M 2005/14252 with needle insertion means
• CPC Class Codes: A61M 2005/14256 with means for preventing access to the needle after use
• CPC Class Codes: A61M 2005/1586 Holding accessories for holding infusion needles on the body holding devices for catheters A61M25/02
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/158 Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/322 Retractable needles, i.e. disconnected from and withdrawn into the syringe barrel by the piston devices for protecting guide needles in combination with catheters A61M25/0612
• CPC Class Codes: A61M 5/3232 Semi-automatic needle retraction, i.e. in which triggering of the needle retraction requires a deliberate action by the user, e.g. manual release of spring-biased retraction means
• CPC Class Codes: A61M 5/3234 Fully automatic needle retraction, i.e. in which triggering of the needle does not require a deliberate action by the user

Abstract

A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.

Claims

1. A fluid delivery device comprising:

a housing configured to be coupled to a skin surface in an engaged position;

a fluid reservoir coupled to the housing;

an actuator coupled to the housing and configured to deliver a force to the fluid reservoir, the actuator having a first position and a second position; and

a needle assembly having a needle, the needle having a delivery end configured to extend from the housing and into the skin surface in a delivery configuration, the needle assembly being configured to automatically withdraw the delivery end of the needle into the housing upon the actuator moving from the first position to the second position;

a locking member configured to keep the delivery end of the needle within the housing in a locked position; and

an actuation button coupled to the needle and having a sleeve surrounding at least a portion of the needle, wherein the locking member is spring biased toward the sleeve, the sleeve having at least one abutment surface configured to engage with the locking member to prevent at least one of engaging and disengaging the needle.

2. The fluid delivery device of claim 1 further comprising:

a needle release configured to position the locking member into the locked position upon the actuator moving from the first position into the second position.

3. The fluid delivery device of claim 2, wherein the needle release is spring biased toward the locking member in the first position.

4. The fluid delivery device of claim 3, wherein the needle release includes at least one projection configured to engage with the locking member.

5. The fluid delivery device of claim 4, wherein the at least one projection is ramped.

6. The fluid delivery device of claim 1, wherein the at least one abutment surface includes a first abutment surface and a second abutment surface, the locking member engageable with the first abutment surface to releaseably retain the needle in the engaged position, the locking member engageable with the second abutment surface to unreleaseably retain the needle in the locked position.

7. The fluid delivery device of claim 6, wherein the first abutment surface is axially spaced along the needle from the second abutment surface and the actuation button is configured to be spring biased away from the skin surface in the delivery configuration.

8. The fluid delivery device of claim 1, wherein the locking member comprises a helical torsion spring.

9. The fluid delivery device of claim 1, wherein the locking member is configured to releaseably retain the needle in the engaged position.

10. The fluid delivery device of claim 1 further comprising:

a first hydraulic chamber;

a second hydraulic chamber; and

a flow restrictor fluidly coupling the first hydraulic chamber and a second hydraulic chamber, wherein the actuator is configured to deliver the force to the fluid reservoir through the first and second hydraulic chambers.

11. The fluid delivery device of claim 1, wherein the actuator reaches an end of travel in the second position.

12. The fluid delivery device of claim 1, wherein fluid is delivered through the needle in the first position and the fluid ceases to be delivered from the needle in the second position.

13. The fluid delivery device of claim 1, wherein the housing includes a bottom surface, the bottom surface including an adhesive configured to releaseably couple the housing to the skin surface in the engaged position.

14. A fluid delivery device comprising:

a housing configured to be coupled to a skin surface in an engaged position;

a fluid reservoir coupled to the housing;

an actuator coupled to the housing and configured to deliver a force to the fluid reservoir, the actuator having a first position and a second position; and

a needle assembly having a needle, the needle having a delivery end configured to extend from the housing and into the skin surface in a delivery configuration, the needle assembly being configured to automatically withdraw the delivery end of the needle into the housing upon the actuator moving from the first position to the second position;

a locking member configured to keep the delivery end of the needle within the housing in a locked position; and

a needle release configured to position the locking member into the locked position upon the actuator moving from the first position into the second position,

wherein the needle release is spring biased, the needle release being retained in the first position by a lock release coupled to the actuator, the lock release configured to release the needle release and allow the needle release to move in a direction of the spring bias in the second position.

15. The fluid delivery device of claim 14, wherein the lock release includes a shaft extending from the actuator.

16. A fluid delivery device comprising:

a housing having a bottom surface, the bottom surface including an adhesive configured to releaseably couple the housing to a skin surface in an engaged position;

a needle assembly having a needle, the needle having a delivery end configured to extend from the housing and into the skin surface in a delivery configuration, the needle assembly being configured to automatically withdraw the delivery end of the needle into the housing upon decoupling the bottom surface of the housing from the skin surface;

a locking member configured to keep the delivery end of the needle within the housing in a locked position;

a needle release configured to position the locking member into the locked position upon decoupling the housing from the skin surface; and

a lock release configured to compress a spring biasing the needle release in the engaged position, the spring configured to move the needle release upon decoupling the housing from the skin surface.

17. The fluid delivery device of claim 16, wherein the needle release includes at least one projection configured to engage with the locking member.

18. The fluid delivery device of claim 17, wherein the at least one projection is ramped.

19. The fluid delivery device of claim 16, wherein the needle release is spring biased toward the skin surface in the engaged position.

20. The fluid delivery device of claim 16, wherein the needle release is contained within the housing in the engaged position and extends from the housing in the locked position.

21. The fluid delivery device of claim 16 further comprising:

an actuation button coupled to the needle and having a sleeve surrounding at least a portion of the needle, wherein the locking member is spring biased toward the sleeve, the sleeve having at least one abutment surface configured to engaging with the locking member to prevent at least one of engaging and disengaging the needle.

22. The fluid delivery device of claim 21, wherein the at least one abutment surface includes a first abutment surface and a second abutment surface, the locking member engageable with the first abutment surface to releaseably retain the needle in the engaged position, the locking member engageable with the second abutment surface to unreleaseably retain the needle in the locked position.

23. The fluid delivery device of claim 22, wherein the first abutment surface is axially spaced along the needle from the second abutment surface and the actuation button is configured to be spring biased away from the skin surface in the delivery configuration.

24. The fluid delivery device of claim 16, wherein the locking member comprises a helical torsion spring.

25. The fluid delivery device of claim 16, wherein the locking member is configured to releaseably retain the needle in the engaged position.

26. The fluid delivery device of claim 16 further comprising:

a fluid reservoir coupled to the housing; and

an actuator coupled to the housing and configured to deliver a force to the fluid reservoir.

27. The fluid delivery device of claim 26 further comprising:

a first hydraulic chamber;

a second hydraulic chamber; and

a flow restrictor fluidly coupling the first hydraulic chamber and a second hydraulic chamber, wherein the actuator is configured to deliver a force to the fluid reservoir through the first and second hydraulic chambers.

28. The fluid delivery device of claim 26, wherein the actuator includes a first position and a second position, and wherein the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon the actuator moving from the first position to the second position.