Cannula for minimizing dilution of dosing during nitric oxide delivery
First Claim
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1. A nasal cannula for therapeutic gas delivered to a patient, comprising:
- a nitric oxide source;
an oxygen source;
a first lumen, a second lumen, and a third lumen;
the first lumen being a first therapeutic gas lumen for delivering a first therapeutic gas comprising nitric oxide from the nitric oxide source to the patient,the second lumen being a triggering lumen, andthe third lumen being a second therapeutic gas lumen for delivering a second therapeutic gas comprising oxygen from the oxygen source to the patient; and
a cannula nosepiece allowing separate flow paths to the patient for each of (i) the first therapeutic gas lumen, (ii) the triggering lumen, and (iii) the second therapeutic gas lumen; and
wherein the cannula nosepiece comprises a nitric oxide flow path having an inner diameter that is smaller than an inner diameter of the first therapeutic gas lumen.
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Abstract
Described are nasal cannulas that improve the precision of the delivered dose for nitric oxide therapy by reducing the dilution of nitric oxide. The nasal cannulas may reduce the total volume and potential for retrograde flow during nitric oxide therapy through the design of the specific dimensions of the flow path and/or having check valves in the nitric oxide delivery line and/or having a flapper or umbrella valve dedicated to nitric oxide delivery. The nasal cannulas may also use materials that limit oxygen diffusion through the cannula walls. The nosepiece for these cannulas may be manufactured by a molding technique.
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Citations
21 Claims
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1. A nasal cannula for therapeutic gas delivered to a patient, comprising:
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a nitric oxide source; an oxygen source; a first lumen, a second lumen, and a third lumen; the first lumen being a first therapeutic gas lumen for delivering a first therapeutic gas comprising nitric oxide from the nitric oxide source to the patient, the second lumen being a triggering lumen, and the third lumen being a second therapeutic gas lumen for delivering a second therapeutic gas comprising oxygen from the oxygen source to the patient; and a cannula nosepiece allowing separate flow paths to the patient for each of (i) the first therapeutic gas lumen, (ii) the triggering lumen, and (iii) the second therapeutic gas lumen; and wherein the cannula nosepiece comprises a nitric oxide flow path having an inner diameter that is smaller than an inner diameter of the first therapeutic gas lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A nasal cannula for therapeutic gas delivered to a patient, comprising:
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a nitric oxide source; an oxygen source; a first lumen and a second lumen; the first lumen being a combined first therapeutic gas and triggering lumen for both delivering a first therapeutic gas comprising nitric oxide from the nitric oxide source to the patient and triggering, and the second lumen being a second therapeutic gas lumen for delivering a second therapeutic gas comprising oxygen from the oxygen source to the patient, the combined first therapeutic gas and triggering lumen having an inner diameter that is smaller than an inner diameter of the second therapeutic gas lumen; and a cannula nosepiece allowing separate flow paths to the patient for each of (i) the combined first therapeutic gas and triggering lumen and (ii) the second therapeutic gas lumen; and wherein the cannula nosepiece comprises a nitric oxide flow path having an inner diameter that is smaller than an inner diameter of the combined first therapeutic gas and triggering lumen. - View Dependent Claims (9, 10, 11, 12)
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13. A method of administering nitric oxide for treating pulmonary hypertension, the method comprising:
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administering a pulse of a gas comprising nitric oxide to a patient, wherein the pulse is administered through a nasal cannula comprising; a first lumen, a second lumen, and a third lumen; the first lumen being a first therapeutic gas lumen which delivers a gas comprising nitric oxide to the patient, the second lumen being a triggering lumen, and the third lumen being a second therapeutic gas lumen which delivers a gas comprising oxygen to the patient; and a cannula nosepiece allowing separate flow paths to the patient for each of (i) the first therapeutic gas lumen, (ii) the triggering lumen, and (iii) the second therapeutic gas lumen; and wherein the cannula nosepiece comprises a nitric oxide flow path having an inner diameter that is smaller than an inner diameter of the first therapeutic gas lumen. - View Dependent Claims (14, 15, 16, 17)
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18. A method of administering nitric oxide for treating pulmonary hypertension, the method comprising:
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administering a pulse of a gas comprising nitric oxide to a patient, wherein the pulse is administered through a nasal cannula comprising; a first lumen and a second lumen; the first lumen being a combined first therapeutic gas and triggering lumen which both delivers a gas comprising nitric oxide to the patient and triggers, and the second lumen being a second therapeutic gas lumen which delivers a gas comprising oxygen to the patient; and a cannula nosepiece allowing separate flow paths to the patient for each of (i) the combined first therapeutic gas and triggering lumen and (ii) the second therapeutic gas lumen; and wherein the cannula nosepiece comprising a nitric oxide flow path having an inner diameter that is smaller than an inner diameter of the combined first therapeutic gas and triggering lumen. - View Dependent Claims (19, 20, 21)
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Specification