Systems and methods for treating dyspnea, including via electrical afferent signal blocking

• US 9,795,784 B2
• Filed: 09/06/2016
• Issued: 10/24/2017
• Est. Priority Date: 08/11/2008
• Status: Expired due to Fees

• Current Assignee: Cibiem, Inc.
• Original Assignee: Cibiem, Inc.
• Inventors: Hlavka, Edwin J., Elliott, Lynn S.
• Primary Examiner(s): Patton, Amanda
• Application Number:
  US15/257,421
• Publication Number:
  US 20160375241A1
• Time in Patent Office: 413 Days
• CPC Class Codes: A61N 1/0556 Cuff electrodes
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

Systems and methods for treating a patient with dyspnea are disclosed. A method in accordance with a particular embodiment includes identifying the patient as suffering from dyspnea, and, based at least in part on identifying the patient as suffering from dyspnea, implanting an electrical signal delivery element within the patient in signal communication with an afferent neural pathway of a carotid body chemoreceptor. The method can further include at least reducing dyspneic sensations in the patient by directing an electrical signal from the electrical signal delivery element to the neural pathway to at least partially block afferent signals from the chemoreceptor.

Claims

1. A method of treating a patient comprising:

delivering an electrical signal from a controller to a signal delivery device;

directing a neural blocking signal from the signal delivery device to a carotid body or a carotid body afferent neuron to modulate an afferent signal from the carotid body; and

shielding a baroreceptor neuron from the neural blocking signal.

2. The method of claim 1 wherein shielding comprises internally shielding a baroreceptor neuron from the neural blocking signal.

3. The method of claim 1, wherein shielding comprises insulating the baroreceptor neuron from the neural blocking signal.

4. The method of claim 3, wherein insulating the baroreceptor neuron from the neural blocking signal comprises electrically insulating the baroreceptor neuron from the neural blocking signal.

5. The method of claim 1, wherein shielding a baroreceptor neuron comprises internally positioning a shield.

6. The method of claim 5, wherein internally positioning a shield comprises internally positioning a shield adjacent the baroreceptor neuron to shield the baroreceptor neuron from the neural blocking signal.

7. The method of claim 1, wherein shielding a baroreceptor neuron comprises internally positioning an insulator so as to insulate the baroreceptor neuron from the neural blocking signal.

8. The method of claim 1, wherein shielding a baroreceptor neuron comprises restricting the neural blocking signal from the baroreceptor neuron.

9. The method of claim 1, wherein modulating an afferent signal from the carotid body comprises at least partially blocking an afferent signal from the carotid body.

10. The method of claim 1, wherein modulating an afferent signal from the carotid body comprises electrically modulating an afferent signal from the carotid body.

11. The method of claim 1, wherein directing a neural blocking signal from the signal delivery device to a carotid body or a carotid body afferent neuron comprising directing a neural blocking signal from the signal delivery device to a carotid body or a carotid body afferent neuron with an implanted device.