Advanced analyte sensor calibration and error detection
First Claim
1. A system for measuring an analyte, the system comprising sensor electronics configured to be operably connected to a continuous analyte sensor, the sensor electronics configured to:
- apply a time-varying signal to the analyte sensor;
measure a peak current from the sensor in response to the applied signal;
determine a sensitivity of the analyte sensor, the determining comprising correlating the peak current to a predetermined sensor sensitivity curve that is a representation of a change in sensitivity over time, the determining further comprising selecting the predetermined sensitivity curve based on the peak current from a plurality of different predetermined sensitivity curves; and
generate estimated analyte concentration values using the determined sensitivity and sensor data generated by the analyte sensor.
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Accused Products
Abstract
Systems and methods for processing sensor data and self-calibration are provided. In some embodiments, systems and methods are provided which are capable of calibrating a continuous analyte sensor based on an initial sensitivity, and then continuously performing self-calibration without using, or with reduced use of, reference measurements. In certain embodiments, a sensitivity of the analyte sensor is determined by applying an estimative algorithm that is a function of certain parameters. Also described herein are systems and methods for determining a property of an analyte sensor using a stimulus signal. The sensor property can be used to compensate sensor data for sensitivity drift, or determine another property associated with the sensor, such as temperature, sensor membrane damage, moisture ingress in sensor electronics, and scaling factors.
118 Citations
27 Claims
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1. A system for measuring an analyte, the system comprising sensor electronics configured to be operably connected to a continuous analyte sensor, the sensor electronics configured to:
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apply a time-varying signal to the analyte sensor; measure a peak current from the sensor in response to the applied signal; determine a sensitivity of the analyte sensor, the determining comprising correlating the peak current to a predetermined sensor sensitivity curve that is a representation of a change in sensitivity over time, the determining further comprising selecting the predetermined sensitivity curve based on the peak current from a plurality of different predetermined sensitivity curves; and generate estimated analyte concentration values using the determined sensitivity and sensor data generated by the analyte sensor. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method for measuring an analyte using a continuous analyte sensor, the method comprising:
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applying a time-varying signal to the analyte sensor; measuring a peak current; using sensor electronics, determining a sensitivity of the analyte sensor, the determining comprising correlating the peak current to a predetermined sensor sensitivity curve that is a representation of a change in sensitivity over time, the determining further comprising selecting the predetermined sensitivity curve based on the peak current from a plurality of different predetermined sensitivity curves; and using said sensor electronics, generating estimated analyte concentration values using the determined sensitivity and sensor data generated by the analyte sensor. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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Specification