Drive mechanism for a medication delivery device and medication delivery device

• US 9,802,004 B2
• Filed: 09/03/2010
• Issued: 10/31/2017
• Est. Priority Date: 09/07/2009
• Status: Active Grant

• Current Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Original Assignee: Sanofi-Aventis Deutschland GmbH (Sanofi )
• Inventors: Raab, Steffen, Arnhold, Sandra
• Primary Examiner(s): Hayman, Imani
• Assistant Examiner(s): Engel, Matthew A
• Application Number:
  US13/393,331
• Publication Number:
  US 20120296286A1
• Time in Patent Office: 2,615 Days
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31551 including axial movement of dose setting member
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
• CPC Class Codes: A61M 5/31585 performed by axially moving actuator, e.g. an injection button
• CPC Class Codes: A61M 5/31593 Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Abstract

A piston rod is arranged in a body and provided with a helical element and an axial element. A guide element, which is arranged in the body and fixed relatively to the body, is coupled to the helical element to guide a helical movement of the piston rod and coupled to the axial element to guide an axial movement of the piston rod. The axial movement allows a priming of the device preceding the helical movement of the piston rod.

Claims

1. A drive mechanism for a medication delivery device, comprising:

a body having a proximal end and a distal end,

a piston rod arranged within the body along an axis of rotation,

a drive member arranged within the body, the drive member being rotationally coupled with the piston rod with respect to the axis of rotation,

the piston rod configured for both a helical movement and a separate axial movement without rotation with respect to the body, the helical movement of the piston rod comprising a rotation around the axis of rotation and a simultaneous shift along the axis of rotation,

the piston rod comprising a guide track, the guide track comprising a helical element and an axial element, and

a guide element arranged within the body, the guide element being fixed relatively to the body, wherein

the guide element is coupled to the guide track in such a manner as to guide both the helical movement and the separate axial movement without rotation of the piston rod, and wherein,

when the guide element is coupled to the helical element and is rotationally fixed relative to the body during medication delivery, the guide element guides the helical movement of the piston rod, and when the same guide element is coupled to the axial element, it guides the axial movement of the piston rod in a distal direction towards the distal end of the body, the axial movement preceding the helical movement.

2. The drive mechanism according to claim 1, wherein the helical element of the piston rod is a screw thread.

3. The drive mechanism according to claim 2, wherein the axial element of the piston rod is an axial groove leading into the screw thread.

4. The drive mechanism according to claim 1, further comprising:

the drive member being rotationally coupled with the piston rod by means of an axial groove of the piston rod, the axial groove having a limit in the direction of the distal end.

5. The drive mechanism according to claim 4, wherein the drive member is arranged in such a manner that it can be shifted towards the distal end, the drive member is coupled with the piston rod by means of an axial thread engaging the axial groove of the piston rod, the drive member shifts the piston rod towards the distal end when the drive member is shifted towards the distal end while the axial thread is in contact with the limit of the axial groove and the guide element is coupled to the axial element of the piston rod.

6. The drive mechanism according to claim 5, wherein the piston rod is provided to be shifted towards the distal end by the drive member in a priming step.

7. The drive mechanism according to claim 1, further comprising:

a dose sleeve being coupled with the piston rod in such a manner as to allow the piston rod to be shifted towards the distal end by means of the dose sleeve.

8. The drive mechanism according to claim 7, wherein the piston rod is shifted towards the distal end by means of the dose sleeve while the guide element is coupled to the axial element of the piston rod.

9. The drive mechanism according to claim 8, wherein the piston rod is provided to be shifted towards the distal end by the dose sleeve in a priming step.

10. A medication delivery device comprising the drive mechanism according to claim 1, further comprising:

a receptacle at the distal end within the body, and

a piston within the receptacle, the piston being movable along the axis of rotation by means of the piston rod.

11. A medication delivery device according to claim 10, wherein the receptacle is provided for a cartridge, and the piston is inserted in the cartridge.

12. A medication delivery device according to claim 10, wherein a dose is set by a movement of a dose sleeve in the direction to the proximal end, and a medication is delivered by a movement of the dose sleeve in the direction to the distal end.

13. A medication delivery device according to claim 10, wherein the body has a shape of an injection pen.

14. A drive mechanism for a medication delivery device, comprising:

a body having a proximal end and a distal end,

a piston rod having a distal end and arranged within the body along an axis of rotation,

a drive member arranged within the body, the drive member being rotationally coupled with the piston rod with respect to the axis of rotation, the piston rod configured for both a helical movement and a separate axial movement without rotation with respect to the body, the helical movement of the piston rod comprising a rotation around the axis of rotation and a simultaneous shift along the axis of rotation, the piston rod comprising a guide track comprising a helical element and an axial element,

a guide element arranged within the body, the guide element being rotationally fixed relative to the body during medication delivery, wherein the guide element is coupled to the guide track in such a manner as to guide the movement of the piston rod,

a stop member arranged within the body and being rotationally coupled with the body,

a drive sleeve arranged within the body on a side of the drive member facing the proximal end, the drive sleeve being rotatable with respect to the body around the axis of rotation, and

a first gear coupling the drive member and the stop member rotationally when the drive sleeve is rotated in a first sense of rotation around the axis of rotation.

15. The drive mechanism according to claim 14, further comprising:

a spring arranged within the body, the spring exerting a force on the stop member in a proximal direction towards the proximal end,

a second gear coupling the drive member and the drive sleeve rotationally when the drive sleeve is rotated in a second sense of rotation, which is opposite to the first sense of rotation, around the axis of rotation,

a dose sleeve arranged within the body, the dose sleeve being helically movable with respect to the body, the movement comprising a rotation around the axis of rotation and a simultaneous shift along the axis of rotation, and

a coupling between the dose sleeve and the drive sleeve, the coupling producing a rotation of the drive sleeve in the second sense of rotation around the axis of rotation when the dose sleeve is moved towards the distal end.

16. The drive mechanism according to claim 15, wherein the helical movement of the piston rod advances the piston rod towards the distal end when the piston rod is rotated in the second sense of rotation with respect to the body.

17. The drive mechanism of claim 14 where the piston rod moves helically relative to the guide element during dose delivery.

18. A drive mechanism for a medication delivery device, comprising:

a body having a proximal end and a distal end,

a piston rod arranged within the body along an axis of rotation, the piston rod having a distal end,

a drive member arranged within the body, the drive member being rotationally coupled with the piston rod with respect to the axis of rotation,

the piston rod being helically movable with respect to the body, the helical movement of the piston rod comprising a rotation around the axis of rotation and a simultaneous shift along the axis of rotation,

the piston rod comprising a guide track, the guide track comprising a helical element and an axial element, and

a guide element arranged within the body, the guide element being fixed relatively to the body, wherein

the guide element is rotationally fixed relative to the body during medication delivery and is coupled to the guide track in such a manner as to cause first the axial movement without the helical movement followed by the helical movement of the piston rod, and wherein,

the helical element of the guide track is arranged further away from the distal end than the axial element of the guide track.