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Applying pixelwise descriptors to a target image that are generated by segmenting objects in other images

  • US 9,805,248 B2
  • Filed: 11/26/2015
  • Issued: 10/31/2017
  • Est. Priority Date: 08/29/2014
  • Status: Active Grant
First Claim
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1. A method comprising:

  • dividing digital images of stained tissue of cancer patients into tiles;

    separating the tiles into clusters whose tiles have pixel characteristics that are similar;

    identifying a matching cluster of tiles whose pixel characteristics most closely match the pixel characteristics of a target digital image of stained tissue of a target patient;

    segmenting the tiles of the matching cluster into objects;

    determining object characteristics of the segmented objects;

    assigning a color to each of the object characteristics;

    generating pixelwise descriptors that describe which of the object characteristics a characterized pixel most probably exhibits based on a quality of a second pixel at a predetermined offset from the characterized pixel;

    generating a pixel heat map by applying the pixelwise descriptors to each pixel of the target digital image without segmenting the target digital image into objects, wherein each pixel of the target digital image has the color assigned to the object characteristic most probably exhibited by that pixel; and

    displaying the pixel heat map on a graphical user interface.

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