Fluid extraction or filtration device, associated materials and methods
First Claim
1. A method of treating fluid overload employing a device comprising an array of microneedles for contacting fluid in a body of a patient and an absorbent matrix in fluid communication with said array of microneedles, the method comprisingcontacting said fluid with said array of microneedles such that said fluid flows from said body to said absorbent matrix via said microneedles;
- andremoving fluid from the body of the patient at a rate of at least 10 ml/day and up to 1000 ml/day.
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Accused Products
Abstract
A fluid extraction or filtration device for removing fluid from a body, the device comprising an array of microneedles for contacting fluid in said body and an absorbent gel matrix in fluid communication with said array of microneedles. There is further provided a combined fluid extraction and sampling device and methods employing the device(s), for example in determining the level of a target species in a sample of fluid, transdermal dialysis and renal replacement therapy. There is further provided an absorbent gel matrix for use in the treatment of uraemia and a haemodialysis filter comprising an absorbent gel matrix. Use of such a matrix is described in the context of methods including haemodialysis, transdermal dialysis and gastrointestinal dialysis.
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Citations
18 Claims
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1. A method of treating fluid overload employing a device comprising an array of microneedles for contacting fluid in a body of a patient and an absorbent matrix in fluid communication with said array of microneedles, the method comprising
contacting said fluid with said array of microneedles such that said fluid flows from said body to said absorbent matrix via said microneedles; - and
removing fluid from the body of the patient at a rate of at least 10 ml/day and up to 1000 ml/day. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for transdermal dialysis employing a device comprising an array of microneedles for contacting fluid in a body of a patient in need of dialysis and an absorbent matrix in fluid communication with said array of microneedles, the method comprising:
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contacting said fluid with said array of microneedles such that fluid flows from said body to said absorbent matrix via said microneedles, and removing fluid from the body of the patient at a rate of at least 10 ml/day and up to 1000 ml/day.
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18. A method for renal replacement therapy comprising transdermal dialysis employing a device comprising an array of microneedles for contacting fluid in a body of a patient in need of renal replacement therapy and an absorbent matrix in fluid communication with said array of microneedles, the method comprising:
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contacting said fluid with said array of microneedles such that fluid flows from said body to said absorbent matrix via said microneedles, and removing fluid from the body of the patient at a rate of at least 10 ml/day and up to 1000 ml/day.
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Specification