Mode switching by a ventricular leadless pacing device

• US 9,808,628 B2
• Filed: 11/14/2016
• Issued: 11/07/2017
• Est. Priority Date: 11/11/2014
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sheldon, Todd J, Demmer, Wade M
• Primary Examiner(s): FAIRCHILD, MALLIKA DIPAYAN
• Application Number:
  US15/350,708
• Publication Number:
  US 20170056670A1
• Time in Patent Office: 358 Days
• CPC Class Codes: A61N 1/36592 controlled by the heart rate variability
• CPC Class Codes: A61N 1/3688 configured for switching the pacing mode, e.g. from AAI to DDD
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

In some examples, a leadless pacing device (hereinafter, “LPD”) is configured for implantation in a ventricle of a heart of a patient, and is configured to switch between an atrio-ventricular synchronous pacing mode and an asynchronous ventricular pacing mode in response to detection of one or more sensing events, which may be, for example, undersensing events. In some examples, an LPD is configured to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode in response to determining, for a threshold number of cardiac cycles, a ventricular depolarization was not detected within a ventricular event detection window that begins at an atrial activation event.

Claims

1. A system having at least a leadless pacing device, the system comprising:

means for detecting an electric cardiac signal means for detecting a first atrial activation event based on the electrical cardiac signal;

means for determining, based on the electrical cardiac signal, a second atrial activation event was not detected within a detection window that begins at the first atrial activation event; and

means for controlling the leadless pacing device to deliver pacing pulses to a ventricle of a heart according to an asynchronous ventricular pacing mode based on the determination that the second atrial activation event was not detected within the detection window.

2. The system of claim 1, wherein the electrical cardiac signal comprises a first electrical cardiac signal, the system further comprising means for determining the detection window, wherein means for determining the detection window comprises:

means for receiving a second electrical cardiac signal sensed by the leadless pacing device prior to sensing the first electrical cardiac signal;

means for detecting, based on the second electrical cardiac signal, a plurality of atrial activation events;

means for determining intervals between each consecutive two atrial activation events of the plurality of atrial activation events; and

means for determining an average length of the interval between each consecutive two atrial activation events of the plurality of atrial activation events, wherein a duration of the detection window is based on the average length of the interval.

3. The system of claim 1, wherein the electrical cardiac signal comprises a first electrical cardiac signal, the system further comprising means for determining the detection window, wherein means for determining the detection window comprises:

means for receiving a second electrical cardiac signal sensed by the leadless pacing device prior to sensing the first electrical cardiac signal;

means for detecting, based on the second electrical cardiac signal, a first ventricular activation event;

means for detecting, based on the second electrical cardiac signal, a second ventricular activation event, the second ventricular activation event being a next ventricular activation event after the first ventricular activation event; and

means for determining an interval between the first and second ventricular activation events, wherein a duration of the detection window is based on the interval between the first and second ventricular activation events.

4. A system having at least a leadless pacing device, the system comprising:

means for detecting an electric cardiac signal means for detecting, based on the electrical cardiac signal, an atrial activation event;

means for determining, based on the electrical cardiac signal, a ventricular sense event was not detected within a ventricular event detection window that begins at the atrial activation event; and

means for controlling the leadless pacing device to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode based on the determination that the ventricular sense event was not detected within the ventricular event detection window by at least controlling the leadless pacing device to deliver a pacing pulse to a heart according to the atrio-ventricular synchronous pacing mode.

5. The system of claim 4, wherein the means for controlling the leadless pacing device to switch from the sensing without pacing mode to the atrio-ventricular synchronous pacing mode comprises:

a counter;

means for incrementing the counter in response to determining the ventricular sense event was not detected within the detection window;

means for determining, after incrementing the counter, whether a value of the counter is greater than or equal to a threshold value; and

means for controlling, in response to determining the value of the counter is greater than or equal to a threshold value, the leadless pacing device to deliver the pacing pulse according to the atrio-ventricular synchronous pacing.

6. The system of claim 4, wherein the threshold value is one.

7. The system of claim 4, wherein the threshold value is two or three.

8. A non-transitory computer-readable medium comprising instructions that, when executed by a processing module, cause the processing module to:

detect, based on an electrical cardiac signal, an atrial activation event;

determine, based on the electrical cardiac signal, a ventricular sense event was not detected within a ventricular event detection window that begins at the atrial activation event; and

control a leadless pacing device to switch from a sensing without pacing mode to an atrio-ventricular synchronous pacing mode based on the determination that the ventricular sense event was not detected within the ventricular event detection window, wherein controlling the leadless pacing device to switch to the atrio-ventricular synchronous pacing mode comprises controlling the leadless pacing device to deliver a pacing pulse to a heart according to the atrio-ventricular synchronous pacing mode.

9. The non-transitory computer-readable medium of claim 8, wherein the instructions, when executed by a processing module, cause the processing module to switch from the sensing without pacing mode to the atrio-ventricular synchronous pacing mode by at least:

incrementing a counter in response to determining the ventricular sense event was not detected within the detection window;

determining, after incrementing the counter, whether a value of the counter is greater than or equal to a threshold value; and

controlling, in response to determining the value of the counter is greater than or equal to a threshold value, the leadless pacing device to deliver the pacing pulse according to the atrio-ventricular synchronous pacing mode.