Calibration process and system

• US 9,810,703 B2
• Filed: 10/14/2015
• Issued: 11/07/2017
• Est. Priority Date: 12/12/2012
• Status: Active Grant

• Current Assignee: Bio-Rad Laboratories Incorporated
• Original Assignee: Bio-Rad Laboratories Incorporated
• Inventors: Darmstadt, Adam, Waite, Michael, Forni, Theresa
• Primary Examiner(s): Macchiarolo, Peter
• Assistant Examiner(s): Megna Fuentes, Anthony W
• Application Number:
  US14/883,395
• Publication Number:
  US 20160033541A1
• Time in Patent Office: 755 Days
• Field of Search: 422 63- 67
• CPC Class Codes: B01L 2200/148 Specific details about calibrations
• CPC Class Codes: B01L 2300/021 Identification, e.g. bar codes
• CPC Class Codes: B01L 3/527 for a plurality of reagents
• CPC Class Codes: G01N 2030/047 external
• CPC Class Codes: G01N 2035/00702 Curve-fitting; Parameter matching; Calibration constants
• CPC Class Codes: G01N 35/00693 Calibration
• CPC Class Codes: G01N 35/0095 introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]

Abstract

An improved calibration process for a medical testing machine. The machine automatically recognizes that a package of calibration material has been inserted into it, and performs a calibration sequence to ascertain a calibration parameter to be used in performing future tests with the medical testing machine. The calibration package may include machine-readable indicators that the package is to be used for calibration, and of a calibration setpoint of a calibration material in the package. A calibration material may be stored in a lyophilized state in the package, and the medical testing machine may automatically reconstitute the lyophilized material.

Claims

1. A package of calibration material for calibrating a medical testing machine, the package of calibration material comprising:

two different materials, at least one of which is a calibration material;

a respective container for each of the materials, the containers being connected together into a monolithic unit and maintaining separation between the materials before use of the calibration package; and

a machine-readable indicator on the outside of the package, wherein the machine-readable indicator indicates that the package is for calibration of the medical testing machine and wherein the machine-readable indicator is configured for automatically initiating testing of the calibration material in the package;

wherein one of the materials is a fluid configured for preparing a column of a liquid chromatography system for testing.

2. The package of calibration material of claim 1, wherein the containers are connected together at their top ends when the package is in an orientation in which it is placed into the medical testing machine.

3. The package of calibration material of claim 1, wherein at least one of the materials is a calibration material in a lyophilized state.

4. The package of calibration material of claim 1, comprising two calibration materials and the fluid configured for preparing a column of a liquid chromatography for testing, each in a respective container.

5. The package of calibration material of claim 4, wherein the two calibration materials have different setpoints.

6. The package of calibration material of claim 1, wherein the machine-readable indicator is a barcode.

7. The package of calibration material of claim 1, further comprising a second machine-readable indicator on the outside of the package, wherein the second machine-readable indicator indicates a calibration setpoint for one of the materials.

8. The package of calibration material of claim 7, wherein the second machine-readable indicator is a barcode.

9. The package of calibration material of claim 1, wherein the package of calibration materials is in the shape of cylindrical blood collection vials connected together.

10. The package of calibration material of claim 1, wherein each of the containers is cylindrical, and wherein the containers are disposed with their longitudinal axes parallel and their ends aligned, and wherein the containers are joined to each other proximate one end of the cylinders.