Matching geometry generation and display of mammograms and tomosynthesis

• US 9,811,758 B2
• Filed: 06/19/2015
• Issued: 11/07/2017
• Est. Priority Date: 11/15/2004
• Status: Active Grant

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Ren, Baorui, Ruth, Christopher, Smith, Andrew P., Wilson, Kevin, Stein, Jay A.
• Primary Examiner(s): Bayat, Ali
• Application Number:
  US14/744,930
• Publication Number:
  US 20150317538A1
• Time in Patent Office: 872 Days
• Field of Search: 382131
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: G06F 18/22 Matching criteria, e.g. proximity measures
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 11/60 Editing figures and text; Combining figures or text
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 3/02 Affine transformations for image registration G06T3/147; for image mosaicing G06T3/4038
• CPC Class Codes: G06T 7/30 Determination of transform parameters for the alignment of images, i.e. image registration

Abstract

A method and a system for using tomosynthesis projection images of a patient'"'"'s breast to reconstruct slice tomosynthesis images such that anatomical structures that appear superimposed in a mammogram are at conforming locations in the reconstructed images.

Claims

1. A method comprising:

imaging a breast so as to acquire digital information corresponding to a plurality of 2D x-ray tomosynthesis projection images of the breast taken at different angles;

generating, from the digital information, a plurality of reconstructed tomosynthesis images representative of respective breast layers;

obtaining a 2D mammogram image of the breast; and

displaying at least one of the plurality of reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast.

2. The method of claim 1, wherein the displaying operation includes displaying superimposedly at least two of a plurality of images simultaneously.

3. The method of claim 2, wherein the at least two of the plurality of images includes at least one of the plurality of reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast.

4. The method of claim 2, wherein the displaying operation includes displaying two of the plurality of reconstructed tomosynthesis images representative of respective breast layers.

5. The method of claim 1, wherein each of the plurality of reconstructed tomosynthesis images representative of respective breast layers has a layer thickness corresponding to a thickness of a breast that is less than a total thickness of the breast.

6. The method of claim 1, wherein each of the plurality of reconstructed tomosynthesis images representative of respective breast layers are parallel to an image plane of the 2D mammogram image of the breast.

7. The method of claim 1, wherein the obtaining operation comprises directing an x-ray at the breast.

8. The method of claim 1, wherein at least one of the plurality of the reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast are displayed alternately.

9. The method of claim 1, wherein at least one of the plurality of the reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast are displayed simultaneously.

10. The method of claim 1, wherein at least one of the plurality of the reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast are displayed superimposedly.

11. The method of claim 1, further comprising displaying, based on an input, at least one of the plurality of the reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast.

12. The method of claim 1, further comprising:

identifying a first location on at least one of the reconstructed tomosynthesis images representative of respective breast layers and a second location on the 2D mammogram image of the breast, wherein both of the first location and the second location correspond to a single predetermined location within the breast.

13. The method of claim 9, further comprising displaying a marker corresponding to the single predetermined location on at least one of the reconstructed tomosynthesis images representative of respective breast layers and the 2D mammogram image of the breast.

14. The method of claim 1, further comprising:

identifying a location on the 2D mammogram image of the breast; and

displaying a marker corresponding to the location on at least one of the reconstructed tomosynthesis images representative of respective breast layers.

15. The method of claim 14, wherein the location corresponds to a suspected abnormality.

16. A method comprising:

displaying a tomosynthesis image representative of a layer of a breast;

displaying a 2D mammogram image of the breast; and

superimposing a marker on each of the displayed tomosynthesis image and the displayed 2D mammogram image, wherein the marker corresponds to a single predetermined location within the breast.

17. The method of claim 16, wherein the tomosynthesis image representative of the slice of the breast is parallel to an image plane of the 2D mammogram image of the breast.

18. The method of claim 16, further comprising obtaining digital information regarding at least one of the tomosynthesis image and the 2D mammogram image from an imaging system.

19. The method of claim 16, wherein the tomosynthesis image and the 2D mammogram image are displayed alternately.

20. The method of claim 16, wherein the tomosynthesis image and the 2D mammogram image are displayed simultaneously.