Bone oxygenation measurement

• US 9,814,393 B1
• Filed: 07/29/2014
• Issued: 11/14/2017
• Est. Priority Date: 02/23/2010
• Status: Active Grant

• Current Assignee: ViOptix, Inc.
• Original Assignee: ViOptix, Inc.
• Inventors: Mao, Jimmy Jian-Min, Lash, Robert E.
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US14/446,222
• Time in Patent Office: 1,204 Days
• CPC Class Codes: A61B 2562/0238 Optical sensor arrangements for performing transmission measurements on body tissue
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/4504 Bones A61B5/4547 takes precedence
• CPC Class Codes: A61B 5/6847 mounted on an invasive device
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence
• CPC Class Codes: A61B 5/725 using specific filters therefor, e.g. Kalman or adaptive filters A61B5/316 take precedence
• CPC Class Codes: Y10T 29/49002 Electrical device making
• CPC Class Codes: Y10T 29/49169 Assembling electrical component directly to terminal or elongated conductor

Abstract

A bone oximeter probe includes an elongated member and a sensor head at an end of the elongated member to make measurements for a bone. The measurements can indicate the viability or nonviability of the bone. In an implementation, the probe is advanced through an incision in soft tissue, towards the underlying bone, and positioned so that the sensor head faces the bone to be measured. Optical signals are sent from the sensor head and into the bone. The bone reflects some of the optical signals which are then detected so that measurements for the bone can be made. Some of these measurements include an oxygen saturation level value, and a total hemoglobin concentration value of the bone.

Claims

1. A medical device comprising a probe for making an oxygen saturation measurement for a bone, the probe comprising:

a rigid elongated member, wherein the rigid elongated member comprises a proximal end, a distal end opposite the proximal end, and a smooth outer surface therebetween;

a sensor head, coupled to the distal end of the rigid elongated member, wherein the sensor head comprises;

first and second openings; and

first and second fiber optic cables, wherein the first fiber optic cable is coupled to the first opening, and the second fiber optic cable is coupled to the second opening, and

wherein the sensor head is positioned so that light directed into the bone via the first fiber optic cable travels in a first direction from the proximal end towards the distal end and exits the first opening in the first direction, and light reflected from the bone enters the second opening in a second direction, and travels from the distal end towards the proximal end in the second direction and through the second fiber optic cable;

a flexible tube, extending from the proximal end of the rigid elongated member; and

a connector, coupled to the flexible tube.

2. The medical device of claim 1 comprising a beam combiner, external to the probe, wherein the beam combiner comprises:

a first input coupled to a first radiation source of a first wavelength; and

a second input coupled to a second radiation source of a second wavelength, different from the first wavelength, wherein the first fiber optic cable is coupled to the beam combiner and outputs light of the first wavelength and light of the second wavelength.

3. The medical device of claim 1 wherein a length of the rigid elongated member is from about 10 centimeters to about 50 centimeters.

4. The medical device of claim 1 wherein the rigid elongated member is a solid rod and the first and second fiber optic cables are coupled to a side surface of the solid rod which joins the distal and proximal ends.

5. The probe of claim 1 wherein the sensor head comprises a deformable material that can conform to a contour of the surface of the bone to be measured.

6. The probe of claim 1 wherein the sensor head comprises third and fourth openings, and in combination with light conducted via the first and second openings, light conducted via the third and fourth openings is used in making an oxygen saturation measurement for the bone.

7. The probe of claim 1 wherein to make an oxygen saturation measurement, the sensor head is adapted to be used on a surface of the bone to be measured.

8. A medical device probe for making a bone oxygen saturation measurement, the probe comprising:

an elongated member, wherein the elongated member comprises a proximal end, and a distal end, opposite the proximal end;

a sensor head, coupled to the elongated member closer to the distal end than the proximal end of the elongated member, wherein the sensor head comprises;

first and second openings; and

first and second fiber optic cables, wherein the first fiber optic cable is coupled to the first opening, and the second fiber optic cable is coupled to the second opening, and

wherein the sensor head is positioned so that light directed into a bone to be measured via the first fiber optic cable travels through the cable to the sensor head and exits the first opening into the bone in a first direction, and light reflected from the bone enters the second opening in a second direction, and travels through the second fiber optic cable in a direction opposite a transmission path of the first light signal;

a flexible tube, slidably extending from the proximal end of the elongated member; and

a connector, coupled to the flexible tube.

9. The probe of claim 8 wherein ends of the first and second fiber optic cables are exposed on a surface of the sensor head, and an axis passing through the elongated member passes through the surface.

10. The probe of claim 8 wherein ends of the first and second fiber optic cables are exposed on a surface of the sensor head, and an axis passing through the elongated member does not pass through the surface.

11. The probe of claim 8 wherein the sensor head comprises:

third and fourth openings; and

third and fourth fiber optic cables, wherein the third fiber optic cable is coupled to the third opening, and the fourth fiber optic cable is coupled to the fourth opening,

wherein ends of the first and second fiber optic cables are exposed on a first surface of the sensor head, and an axis passing through the elongated member passes through the first surface, and

wherein ends of the third and fourth fiber optic cables are exposed on a second surface of the sensor head, and an axis passing through the elongated member does not pass through the second surface.

12. The probe of claim 11 wherein light directed into the bone via the third fiber optic cable travels through the cable to the sensor head and exits the third opening into the bone in a third direction, and light reflected from the bone enters the fourth opening in a fourth direction, and travels through the fourth fiber optic cable in a direction opposite a transmission path of the third first light signal, and

the first and third directions are different from each other.

13. The probe of claim 8 wherein the sensor head and its first and second openings protrude in front of a tip of the elongated member.

14. The probe of claim 8 wherein the sensor head comprises a surface being convex in one direction.

15. The probe of claim 8 wherein the sensor head comprises a surface being convex in at least two directions.

16. The probe of claim 8 wherein the sensor head comprises a surface being concave in one direction.

17. The probe of claim 8 wherein the sensor head comprises a surface being concave in at least two directions.

18. The probe of claim 8 wherein the first and second openings are positioned on a sidewall of the elongated member near a tip of the elongated member.

19. The probe of claim 8 wherein the sensor head comprises a deformable material that can conform to a contour of the surface of the bone to be measured.

20. The probe of claim 19 wherein a first portion of the deformable material comprising the first opening with first fiber optic cable can be subject to compression that is different from a second portion of the deformable material comprising the second opening with second fiber optic cable.