Weight-controlled sorbent system for hemodialysis

• US 9,814,820 B2
• Filed: 12/02/2013
• Issued: 11/14/2017
• Est. Priority Date: 07/19/2002
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Childers, Robert W., Brown, David S., Wariar, Ramesh, Karoor, Sujatha, Din, Shahid, Martis, Leo, Buchmann, Cody, Soltys, Paul
• Primary Examiner(s): Eisenberg, Rebecca E
• Application Number:
  US14/094,306
• Publication Number:
  US 20140083944A1
• Time in Patent Office: 1,443 Days
• CPC Class Codes: A61M 1/1524 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/153 the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/1656 Apparatus for preparing dialysates
• CPC Class Codes: A61M 1/1658 Degasification
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/285 Catheters therefor
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2202/0413 Blood
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3327 Measuring

Abstract

A hemodialysis system including (i) a dialyzer, (ii) a blood circuit including a blood pump in fluid communication with the dialyzer, (iii) a dialysate circuit including a dialysate circulation pump in fluid communication with the dialyzer, the dialysate circuit further including a sorbent cartridge for cleaning used dialysate, (iv) a dialysate reservoir, (v) a reservoir pump in fluid communication with the dialysate circuit and the dialysate reservoir, (vi) a supply of concentrate for reconstituting dialysate in the dialysate circuit, and (vii) wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate.

Claims

1. A hemodialysis system comprising:

a dialyzer;

a blood circuit including a blood pump in fluid communication with the dialyzer, an arterial line for removing blood from a patient, and a venous line for returning blood to the patient;

a dialysate circuit including a dialysate circulation pump in fluid communication with the dialyzer, the dialysate circuit further including a sorbent cartridge for cleaning used dialysate;

a dialysate reservoir;

a reservoir pump in fluid communication with the dialysate circuit and the dialysate reservoir;

a supply of concentrate for reconstituting dialysate in the dialysate circuit; and

wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate.

2. The hemodialysis system of claim 1, wherein the dialysate reservoir holds an initial batch of dialysate.

3. The hemodialysis system of claim 1, wherein the dialysate reservoir and the supply of concentrate are weighed by a same electronic balance.

4. The hemodialysis system of claim 1, wherein the reservoir pump is positioned and arranged to also pump concentrate from the concentrate supply.

5. The hemodialysis system of claim 4, which includes a first valve positioned between the dialysis reservoir and the reservoir pump and a second valve positioned between the concentrate supply and the reservoir pump.

6. The hemodialysis system of claim 1, which includes a check valve positioned and arranged to prevent regenerated dialysate exiting the sorbent cartridge from reentering the sorbent cartridge.

7. The hemodialysis system of claim 1, which includes a sensor positioned and arranged in the blood circuit for preventing air from being delivered to the patient.

8. The hemodialysis system of claim 1, which includes a sensor positioned and arranged to monitor regenerated dialysate exiting the sorbent cartridge.

9. The hemodialysis system of claim 8, wherein the sensor includes at least one of an ammonia sensor, an ammonium sensor, a pH sensor, or a capacitance sensor.

10. The hemodialysis system of claim 1, which includes a sensor positioned and arranged to monitor an efficiency of the system in removing toxins.

11. The hemodialysis system of claim 1, which includes a sensor positioned and arranged so that its output can be used to control a rate of flow from the supply of concentrate.

12. The hemodialysis system of claim 1, wherein the reservoir pump is positioned and arranged to pump the dialysate from the dialysate reservoir to the dialysate circuit.

13. The hemodialysis system of claim 1, wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate during at least one of (i) a priming of the hemodialysis system, or (ii) a dialysis treatment.

14. A hemodialysis system comprising:

a dialyzer;

a blood circuit including a blood pump in fluid communication with the dialyzer;

a dialysate circuit including a dialysate circulation pump in fluid communication with the dialyzer, the dialysate circuit further including a sorbent cartridge for cleaning used dialysate;

a dialysate reservoir;

a reservoir pump in fluid communication with the dialysate circuit and the dialysate reservoir;

a supply of concentrate for reconstituting dialysate in the dialysate circuit; and

wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate, and

wherein the reservoir pump is positioned and arranged to also pump concentrate from the concentrate supply.

15. The hemodialysis system of claim 14, which includes a first valve positioned between the dialysis reservoir and the reservoir pump and a second valve positioned between the concentrate supply and the reservoir pump.

16. The hemodialysis system of claim 14, which includes a check valve positioned and arranged to prevent regenerated dialysate exiting the sorbent cartridge from reentering the sorbent cartridge.

17. The hemodialysis system of claim 14, which includes a sensor positioned and arranged in the blood circuit for preventing air from being delivered to the patient.

18. The hemodialysis system of claim 14, which includes a sensor positioned and arranged to monitor regenerated dialysate exiting the sorbent cartridge.

19. The hemodialysis system of claim 18, wherein the sensor includes at least one of an ammonia sensor, an ammonium sensor, a pH sensor, or a capacitance sensor.

20. The hemodialysis system of claim 14, which includes a sensor positioned and arranged to monitor an efficiency of the system in removing toxins.

21. The hemodialysis system of claim 14, which includes a sensor positioned and arranged so that its output can be used to control a rate of flow from the supply of concentrate.

22. The hemodialysis system of claim 14, wherein the reservoir pump is positioned and arranged to pump the dialysate from the dialysate reservoir to the dialysate circuit.

23. The hemodialysis system of claim 14, wherein the hemodialysis system is configured to electronically weigh the dialysate reservoir and the supply of concentrate during at least one of (i) a priming of the hemodialysis system, or (ii) a dialysis treatment.